Antonio Baldi
A5051285441- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- COVID-19 and healthcare impacts
- Stroke Rehabilitation and Recovery
- Long-Term Effects of COVID-19
- Lipoproteins and Cardiovascular Health
- Climate Change and Health Impacts
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disorders and Treatments
- Alzheimer's disease research and treatments
- Cardiac Valve Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Tryptophan and brain disorders
- Health Systems, Economic Evaluations, Quality of Life
- Trigeminal Neuralgia and Treatments
- Neurological Disease Mechanisms and Treatments
- Pain Mechanisms and Treatments
- Migraine and Headache Studies
- Neurofibromatosis and Schwannoma Cases
Ospedale di San Donà di Piave
2014-2023
Azienda Ospedaliero-Universitaria di Modena
2023
Laboratoire Lorrain de Recherche en Informatique et ses Applications
2023
University of Modena and Reggio Emilia
2023
Liverpool Heart and Chest Hospital
2023
Liverpool John Moores University
2023
University of Liverpool
2023
St. Anne's University Hospital Brno
2017
University Hospital of Alexandroupolis
2017
Democritus University of Thrace
2017
Background and Purpose— The best time for administering anticoagulation therapy in acute cardioembolic stroke remains unclear. This prospective cohort study of patients with atrial fibrillation, evaluated (1) the risk recurrent ischemic event severe bleeding; (2) factors recurrence (3) risks bleeding associated anticoagulant its starting after stroke. Methods— primary outcome this multicenter was composite stroke, transient attack, symptomatic systemic embolism, cerebral major extracranial...
Background and Purpose- Despite treatment with oral anticoagulants, patients nonvalvular atrial fibrillation (AF) may experience ischemic cerebrovascular events. The aims of this case-control study in AF were to identify the pathogenesis risk factors for events occurring during non-vitamin K antagonist anticoagulants (NOACs) therapy stroke prevention. Methods- Cases consecutive who had acute NOAC treatment. Controls did not have NOACs Results- Overall, 713 cases (641 strokes 72 transient...
In patients with atrial fibrillation who suffered an ischemic stroke while on treatment nonvitamin K antagonist oral anticoagulants, rates and determinants of recurrent events major bleedings remain uncertain.This prospective multicenter observational study aimed to estimate the bleeding their in follow-up consecutive acute cerebrovascular event anticoagulant treatment. Afterwards, we compared estimated risks between whom therapy was changed those continued original treatment.After a mean...
Background and Purpose— The beneficial effect of intravenous thrombolytic therapy in patients with acute ischemic stroke attributable to internal carotid artery (ICA) occlusion remains unclear. aim this study was evaluate the efficacy safety recombinant tissue-type plasminogen activator these patients. Methods— ICARO a case-control multicenter on prospectively collected data. Patients ICA treated within 4.5 hours from symptom onset (cases) were compared matched not (controls). Cases controls...
Background In patients with acute ischemic stroke and atrial fibrillation, early anticoagulation prevents recurrence but the risk of hemorrhagic transformation ( HT ). The aims this study were to evaluate in consecutive fibrillation (1) incidence HT, (2) time initiation , (3) association recurrences, (4) clinical outcome at 90 days. Methods Results was diagnosed by a second brain computed tomographic scan performed 24 72 hours after onset. recurrences as well mortality or disability...
We aimed to investigate the rate of hospital admissions for cerebrovascular events and revascularization treatments acute ischemic stroke in Italy during coronavirus disease 2019 (COVID-19) outbreak.
Previous studies suggested potential ethnic differences in the management and outcomes of atrial fibrillation (AF). We aim to analyse oral anticoagulant (OAC) prescription, discontinuation, risk adverse Asian patients with AF, using data from a global prospective cohort study.From GLORIA-AF Registry Phase II-III (November 2011-December 2014 for II, January 2014-December 2016 III), we analysed according their self-reported ethnicity (Asian vs. non-Asian), as well subgroups (Chinese, Japanese,...
In Alzheimer disease (AD) inflammation becomes evident throughout the course of disease. However, association between inflammation, cognitive impairment, and cerebrospinal biomarkers (Aβ42, t-tau, p-tau181, Aβ42/p-tau181 ratio) is poorly understood.A large panel inflammatory cytokines (interleukin [IL]-1β, IL-1ra, IL-2, IL-4, IL-6, IL-10, IL-17, interferon-γ, tumor necrosis factor-α, vascular endothelial growth factor) was analyzed using a multiplex immunoassay in 27 patients with diagnosis...
Introduction: The efficacy and safety of statins for secondary prevention in patients who have experienced a cardioembolic stroke are not well-defined. However, previous observational data reported hyperlipidemia as risk factor both ischemic bleeding complications with AF stroke. Based on these premises, we conducted sub-analysis the RAF RAF-NOAC studies to evaluate acute AF. Materials methods: We combined patient from studies, prospective across Stroke Units Europe, United States, Asia...
<i>Background:</i> The optimal management of patients with cryptogenic ischemic stroke found to have a patent foramen ovale (PFO) at diagnostic workup remains unclear. aims this observational multicenter study were evaluate: (1) the risk recurrent cerebrovascular events in minor or transient attack (TIA) and PFO who either underwent percutaneous closure received only medical treatment, (2) factors associated events. <i>Methods:</i> Consecutive (aged 55 years less)...
This study was designed to derive and validate a score predict early ischemic events major bleedings after an acute stroke in patients with atrial fibrillation.The derivation cohort consisted of 854 fibrillation included prospective series between January 2012 March 2014. Older age (hazard ratio 1.06 for each additional year; 95% confidence interval, 1.00-1.11) severe enlargement ratio, 2.05; 1.08-2.87) were predictors outcome (stroke, transient attack, systemic embolism) at 90 days from...
Background and Purpose— Bridging therapy with low-molecular-weight heparin reportedly leads to a worse outcome for acute cardioembolic stroke patients because of higher incidence intracerebral bleeding. However, this practice is common in clinical settings. This observational study aimed compare (1) the profiles receiving not bridging therapy, (2) overall group outcomes, (3) outcomes according type anticoagulant prescribed. Methods— We analyzed data from prospective RAF RAF-NOACs studies....
Abstract Aims Chronic Obstructive Pulmonary Disease (COPD) may influence management and prognosis of Atrial Fibrillation (AF), but this relationship has been scarcely explored in contemporary global cohorts. We aimed to investigate the association between AF COPD, relation treatment patterns major outcomes. Methods From prospective, GLORIA-AF Registry, we analysed factors associated with COPD diagnosis, as well risk outcomes COPD. Primary outcome was composite all-cause death adverse...
Introduction: Ischaemic stroke patients with atrial fibrillation (AF) are at high risk of recurrence despite oral anticoagulation therapy. Patients cardiovascular comorbidities may take both antiplatelet and therapy (OAC/AP). Our study aims to evaluate the safety efficacy OAC/AP as secondary prevention in people AF ischaemic stroke. methods: We performed a post-hoc analysis pooled individual data from multicenter prospective cohort studies compared outcomes on DOAC/VKA alone (OAC cohort)....
Abstract The 2MACE score was specifically developed as a risk-stratification tool in atrial fibrillation (AF) to predict cardiovascular outcomes. We evaluated the predictive ability of GLORIA-AF registry. All eligible patients from phase II/III prospective global registry were included. Major adverse cardiac events (MACEs) defined composite outcome stroke, myocardial infarction and death. Cox proportional hazards used examine relationship between study Predictive capability investigated...
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Introduction: Patients with ischemic stroke (IS) and atrial fibrillation (AF) face a higher risk of recurrent vascular events. This study evaluates the impact atherosclerotic disease burden across different territories on events in patients recent AF within 90 days. Methods: We included IS from International RAF network prospective 90-day follow-up. Atherosclerotic was identified by at least one following: Symptomatic heart disease, symptomatic peripheral artery internal carotid stenosis...
Introduction Atrial fibrillation is an independent risk factor of thromboembolism. Women with atrial are at a higher overall for stroke compared to men fibrillation. The aim this study was evaluate sex differences in patients acute and fibrillation, regarding factors, treatments received outcomes. Methods Data were analyzed from the “Recurrence Cerebral Bleeding Patients Acute Ischemic Stroke Fibrillation” (RAF-study), prospective, multicenter, international including only followed up 90...
The aim of this study in patients with acute posterior ischaemic stroke (PS) and atrial fibrillation (AF) was to evaluate (1) the risks recurrent event severe bleeding (2) these relation oral anticoagulant therapy (OAT) its timing. Patients PS were prospectively included; outcome events compared those anterior (AS) which taken from previous registries. primary composite recurrence, transient attack, symptomatic systemic embolism, cerebral major extracranial occurring within 90 days stroke. A...
Background and Purpose: The optimal timing for starting oral anticoagulant after an ischemic stroke related to atrial fibrillation remains a challenge, mainly in patients treated with systemic thrombolysis or mechanical thrombectomy. We aimed at assessing the incidence of early recurrence major bleeding acute thrombolytic therapy and/or thrombectomy, who then received anticoagulants secondary prevention. Methods: combined dataset RAF RAF-NOACs (Early Recurrence Major Bleeding Patients With...
Efficiency of care chain response and hospital reactivity were are challenged for stroke acute management during the pandemic period coronavirus disease 2019 (COVID-19) in North-Eastern Italy (Veneto, Friuli-Venezia-Giulia, Trentino-Alto-Adige), counting 7,193,880 inhabitants (ISTAT), with consequences treatment patients ischemic stroke.