Kristian Barlinn
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Long-Term Effects of COVID-19
- Heart Rate Variability and Autonomic Control
- Obstructive Sleep Apnea Research
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular Health and Disease Prevention
- Cardiovascular and Diving-Related Complications
- COVID-19 Clinical Research Studies
- Neurological Disorders and Treatments
- Ultrasound and Hyperthermia Applications
- Cerebral Venous Sinus Thrombosis
- Neuroscience of respiration and sleep
- Antiplatelet Therapy and Cardiovascular Diseases
- COVID-19 and healthcare impacts
- Cardiac Health and Mental Health
- Neurological Disease Mechanisms and Treatments
- Peripheral Artery Disease Management
- Vestibular and auditory disorders
- Photoacoustic and Ultrasonic Imaging
TU Dresden
2016-2025
University Hospital Carl Gustav Carus
2016-2025
United Nations Economic and Social Commission for Asia and the Pacific
2021-2024
Klinik und Poliklinik für Neurologie
2016-2023
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2016-2020
University Hospital Heidelberg
2019
Heidelberg University
2019
University of Tennessee Health Science Center
2015-2017
Beth Israel Deaconess Medical Center
2016-2017
University General Hospital Attikon
2015-2017
Background and Purpose— The best time for administering anticoagulation therapy in acute cardioembolic stroke remains unclear. This prospective cohort study of patients with atrial fibrillation, evaluated (1) the risk recurrent ischemic event severe bleeding; (2) factors recurrence (3) risks bleeding associated anticoagulant its starting after stroke. Methods— primary outcome this multicenter was composite stroke, transient attack, symptomatic systemic embolism, cerebral major extracranial...
This study aims to assess the number of patients with acute ischemic cerebrovascular events seeking in-patient medical emergency care since implementation social distancing measures in coronavirus disease 2019 (COVID-19) pandemic.In this retrospective multicenter study, data on hospital admissions due stroke or transient attack and numbers reperfusion therapies performed weeks 1 15 2020 were collected 4 German academic centers. Poisson regression was used test for a change admission rates...
Background and Purpose— Intracranial atherosclerotic disease is associated with a high risk of stroke recurrence. We aimed to determine accuracy transcranial Doppler screening at laboratories that share the same standardized scanning protocol. Methods— Patients symptoms cerebral ischemia were prospectively studied. Stroke Outcomes Neuroimaging Atherosclerosis (SONIA) criteria used for identification ≥50% stenosis. determined velocity cutoffs ≥70% stenosis on digital subtraction angiography...
Background Treatment of individuals with asymptomatic carotid artery stenosis is still handled controversially. Recommendations for treatment endarterectomy (CEA) are based on trials having recruited patients more than 15 years ago. Registry data indicate that advances in best medical (BMT) may lead to a markedly decreasing risk stroke stenosis. The aim the SPACE-2 trial (ISRCTN78592017) was compare preventive effects BMT alone combination CEA or stenting (CAS), respectively, ≥70% European...
Argatroban is a direct thrombin inhibitor that safely augments recanalization achieved by tissue-type plasminogen activator (tPA) in animal stroke models. The tPA Stroke Study was an open-label, pilot safety study of plus patients with ischemic due to proximal intracranial occlusion.
Background and Purpose— The beneficial effect of intravenous thrombolytic therapy in patients with acute ischemic stroke attributable to internal carotid artery (ICA) occlusion remains unclear. aim this study was evaluate the efficacy safety recombinant tissue-type plasminogen activator these patients. Methods— ICARO a case-control multicenter on prospectively collected data. Patients ICA treated within 4.5 hours from symptom onset (cases) were compared matched not (controls). Cases controls...
Background In patients with acute ischemic stroke and atrial fibrillation, early anticoagulation prevents recurrence but the risk of hemorrhagic transformation ( HT ). The aims this study were to evaluate in consecutive fibrillation (1) incidence HT, (2) time initiation , (3) association recurrences, (4) clinical outcome at 90 days. Methods Results was diagnosed by a second brain computed tomographic scan performed 24 72 hours after onset. recurrences as well mortality or disability...
Introduction: Animal research suggests that HDL cholesterol (HDL-C) ameliorates reperfusion injury, a phenomenon worsens clinical outcome following recanalization therapy for ischemic stroke. Hypothesis: We hypothesized higher HDL-C levels have guarding effect against cerebral injury in human stroke survivors treated with thrombectomy. Methods: included patients anterior circulation large vessel occlusion (acLVO) who underwent thrombectomy from 01/2017 to 01/2023 at tertiary center Germany...
Abstract Background Functional dizziness is one of the most common causes chronic dizziness. Associated psychiatric diseases such as depression and anxiety lead to significant impairment, possibly due autonomic nervous system imbalance. We investigated whether heart rate variability (HRV) biofeedback can modulate function in patients with functional Methods performed a randomized controlled study 24 diagnosed for first time. Patients received six 20 min sessions HRV or no intervention....
Extracranial cerebrovascular injury is believed to be an important cause of neurological in patients who have suffered blunt trauma. The authors sought determine the timing and mechanisms ischemic stroke traumatic (TCVI).This a prospective study all with TCVI were admitted Level I trauma center during 28-month period. All had risk factors for underwent screening CT angiography (CTA) head neck on admission. either or CTA suggesting confirmatory digital subtraction (DSA). Patients...
Background Five randomized controlled trials recently demonstrated efficacy of endovascular treatment in acute ischemic stroke. Telestroke networks can improve stroke care rural areas but their role patients undergoing is unknown. Aim We compared clinical outcomes between anterior circulation transferred after teleconsultation and those directly admitted to a tertiary center. Methods Data derived from consecutive with intracranial large vessel occlusion who underwent January 2010 December...
Abstract Background The impact of direct oral anticoagulants (DOAC) on haematoma size after intracerebral haemorrhage (ICH) compared to no-anticoagulation is controversial and prospective data are lacking. Methods investigator-initiated, multicentre, RASUNOA-prime study enrolled patients with non-traumatic ICH atrial fibrillation while a DOAC, vitamin K antagonist (VKA) or no anticoagulation (non-OAC). Neuroimaging was reviewed centrally blinded group allocation. Primary endpoint expansion...