Dylan Blacquière
- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cerebral Venous Sinus Thrombosis
- Intracranial Aneurysms: Treatment and Complications
- Clinical practice guidelines implementation
- COVID-19 and healthcare impacts
- Palliative Care and End-of-Life Issues
- Telemedicine and Telehealth Implementation
- Blood Coagulation and Thrombosis Mechanisms
- Cardiovascular Health and Disease Prevention
- History of Medical Practice
- Restraint-Related Deaths
- Blood groups and transfusion
- Neuroinflammation and Neurodegeneration Mechanisms
- Transcranial Magnetic Stimulation Studies
- Race, History, and American Society
- Simulation-Based Education in Healthcare
- Moyamoya disease diagnosis and treatment
- Cardiovascular and Diving-Related Complications
United Nations Economic and Social Commission for Asia and the Pacific
2021-2024
Ottawa Hospital
2009-2023
Health and Education Research Management and Epidemiologic Services (United States)
2023
Deleted Institution
2021-2023
Ottawa Hospital Research Institute
2012-2023
University of Ottawa
2010-2023
Google (United States)
2022
University of Calgary
2015-2021
Foothills Medical Centre
2015-2021
St. Michael's Hospital
2021
The 2015 update of the Canadian Stroke Best Practice Recommendations Hyperacute Care guideline highlights key elements involved in initial assessment, stabilization, and treatment patients with transient ischemic attack (TIA), stroke, intracerebral hemorrhage, subarachnoid acute venous sinus thrombosis. most notable change this 5th edition is addition new recommendations for use endovascular therapy stroke proximal intracranial arterial occlusion. This includes an overview infrastructure...
<h3>Importance</h3> Thrombosis with thrombocytopenia syndrome (TTS) has been reported after vaccination the SARS-CoV-2 vaccines ChAdOx1 nCov-19 (Oxford–AstraZeneca) and Ad26.COV2.S (Janssen/Johnson & Johnson). <h3>Objective</h3> To describe clinical characteristics outcome of patients cerebral venous sinus thrombosis (CVST) without TTS. <h3>Design, Setting, Participants</h3> This cohort study used data from an international registry consecutive CVST within 28 days included between March...
Background and Purpose— Hematoma expansion in intracerebral hemorrhage is associated with higher morbidity mortality. The computed tomography (CT) angiographic spot sign highly predictive of expansion, but other morphological features such as fluid levels, density heterogeneity, margin irregularity may also predict particularly centres where CT angiography not readily available. Methods— Baseline noncontrast scans from patients enrolled the Predicting Growth Outcome Intracerebral Hemorrhage...
The seventh edition of the Canadian Stroke Best Practice Recommendations for Rehabilitation and Recovery following includes a new section devoted to provision virtual stroke rehabilitation. This consensus statement uses Grading Recommendations, Assessment, Development Evaluations methodology Appraisal Guidelines Research & Evaluation II principles. A literature search was conducted using PubMed, Embase, Cochrane databases. An expert writing group reviewed all evidence developed...
Emerging data suggest that direct oral anticoagulants may be a suitable choice for anticoagulation cerebral venous thrombosis (CVT). However, conducting high-quality trials in CVT is challenging as it rare disease with low rates of adverse outcomes such major bleeding and functional dependence. To facilitate the design future trials, SECRET (Study Rivaroxaban Cerebral Venous Thrombosis) assessed (1) feasibility recruitment, (2) safety rivaroxaban compared standard-of-care anticoagulation,...
Every year, approximately 62,000 people with stroke and transient ischemic attack are treated in Canadian hospitals. The 2016 update of the Stroke Best Practice Recommendations Telestroke guideline is a comprehensive summary current evidence-based consensus-based recommendations appropriate for use by all healthcare providers system planners who organize provide care to patients following across broad range settings. These focus on telemedicine technologies rapidly identify treat acute...
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Objective Cerebral venous thrombosis (CVT) caused by vaccine‐induced immune thrombotic thrombocytopenia (VITT) is a rare adverse effect of adenovirus‐based severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) vaccines. In March 2021, after autoimmune pathogenesis VITT was discovered, treatment recommendations were developed. These comprised immunomodulation, non‐heparin anticoagulants, and avoidance platelet transfusion. The aim this study to evaluate adherence these its association...
Background Carotid free-floating thrombi (FFT) in patients with acute transient ischaemic attack (TIA)/stroke have a high risk of early recurrent stroke. Management depends on aetiology, which can include local plaque rupture, dissection, coagulopathy, malignancy and cardioembolism. Our objectives were to classify the underlying aetiology FFT estimate proportion stenosis requiring revascularisation. Methods We prospectively enrolled consecutive presenting three comprehensive stroke centres...
Cerebral venous thrombosis (CVT) due to vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe condition, with high in-hospital mortality rates. Here, we report clinical outcomes of patients CVT-VITT after SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) vaccination who survived initial hospitalization.We used data from an international registry developed CVT within 28 days vaccination, collected until February 10, 2022. VITT diagnosis was classified based on the...
Interprofessional practice (IPP) is the accepted standard of care for clients following a stroke. A brief, embedded and evidence-based IPP team simulation was designed to address stroke knowledge competencies students within limited curriculum space. Each required construct collaborative plan their patient during submit evaluation best implementation with evidence interprofessional collaboration (IPC). total 302 (274 on-site, 28 by distance technology) representing four professions comprised...
Background: A recent survey found few guidelines on the provision of palliative care following stroke; none examined efficacy or results any such process. The role patient's family in decision making and conflicts with staff has not been evaluated. We sought to formally evaluate use locally-developed our Acute Stroke Unit (ASU). Methods: retrospectively records 104 patients who died ASU over a two-year period determine if existing were reflected clinical practice, identify that arose. Data...
The determinants of satisfaction for families acute stroke patients receiving palliative care have not been extensively studied. We surveyed to determine how they perceived after stroke.Families palliated ischemic stroke, intracerebral, or subarachnoid hemorrhage were approached. Four weeks the patient's death, administered After-Death Bereaved Family Member Interview with provided.Fifteen participated. Families most satisfied participation in decision making and least attention emotional...
ABSTRACT: We reviewed stroke care delivery during the COVID-19 pandemic at our center and provincial telestroke system. counted referrals to prevention clinic, code strokes, thrombolysis, endovascular thrombectomies, activations of a system from February April 2017–2020. In 2020, there was 28% reduction in clinic referrals, 32% 26% compared prior years. Thrombolysis thrombectomy rates remained constant. Fewer patients received services across spectrum prevention, acute Ontario, Canada, pandemic.
<h3>Objective</h3> To validate a previously proposed filling defect length threshold of >3.8 mm on CT angiography (CTA) to discriminate between free-floating thrombus (FFT) and plaque atheroma. <h3>Methods</h3> This was prospective multicenter observational study 100 participants presenting with TIA/stroke symptoms carotid intraluminal initial CTA. Follow-up CTA obtained within 1 week at weeks 2 4 if the unchanged in length. Resolution or decreased diagnostic FFT, whereas its static...
Thrombolysis in ischemic stroke is contraindicated patients who have had a within 3 months. However, it unclear whether thrombolytic therapy associated with adverse outcomes this population. We report the characteristics and of treated systemic recombinant tissue-type plasminogen activator context known or unknown recent stroke.We identified received despite (within months acute thrombolysis). Clinical radiological findings were collected, including early neurological worsening hemorrhagic...
The "spot sign", first described in 2007, has shown that a focal area of contrast extravasation within an intracerebral haematoma (ICH) can be correlated with expansion. We describe case where time-resolved dynamic CT angiography (dCTA) shows the appearance sign" only later images. This finding highlights importance timing static angiogram which, if performed too early, might result false-negative diagnosis.
Adenovirus-based COVID-19 vaccines are extensively used in low- and middle-income countries (LMICs). Remarkably, cases of cerebral venous sinus thrombosis due to vaccine-induced immune thrombotic thrombocytopenia (CVST-VITT) have rarely been reported from LMICs.We studied the frequency, manifestations, treatment, outcomes CVST-VITT report data an international registry on CVST after vaccination. VITT was classified according Pavord criteria. We compared LMICs high-income (HICs).Until August...
We aimed to evaluate the perceived effectiveness of interventions implemented by Canadian neurology residency programs for 2020-2021 iteration Resident Matching Service (CaRMS).A cross-sectional survey was distributed and final-year medical students who applied at least one program during match cycle. The surveys evaluated pre-interview interview period accessed students.Thirty-five 13 out 15 institutions in Canada with responded survey. Multiple adaptations were implemented, including...