Stephen van Gaal
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Radiation Dose and Imaging
- Cerebral Venous Sinus Thrombosis
- Atrial Fibrillation Management and Outcomes
- Radiology practices and education
- Health, Environment, Cognitive Aging
- Infectious Encephalopathies and Encephalitis
- Musculoskeletal pain and rehabilitation
- Cardiac Arrhythmias and Treatments
- Neurological Complications and Syndromes
- Diet and metabolism studies
- Primary Care and Health Outcomes
- Cardiac electrophysiology and arrhythmias
- Healthcare Quality and Management
- Innovations in Medical Education
- Cytomegalovirus and herpesvirus research
- Cardiovascular Health and Disease Prevention
- Peripheral Artery Disease Management
- Cardiovascular Health and Risk Factors
- Dementia and Cognitive Impairment Research
United Nations Economic and Social Commission for Asia and the Pacific
2021-2024
Arcadia
2024
University of British Columbia
2018-2023
Hôpital de l'Enfant-Jésus
2022
Université Laval
2022
McGill University
2022
Deleted Institution
2022
Queen Elizabeth II Health Sciences Centre
2020
Dalhousie University
2020
Vancouver General Hospital
2019
Emerging data suggest that direct oral anticoagulants may be a suitable choice for anticoagulation cerebral venous thrombosis (CVT). However, conducting high-quality trials in CVT is challenging as it rare disease with low rates of adverse outcomes such major bleeding and functional dependence. To facilitate the design future trials, SECRET (Study Rivaroxaban Cerebral Venous Thrombosis) assessed (1) feasibility recruitment, (2) safety rivaroxaban compared standard-of-care anticoagulation,...
Importance Age is a leading predictor of poor outcomes after brain injuries like stroke. The extent to which age associated with preexisting burdens changes, visible on neuroimaging but rarely considered in acute decision-making or trials, unknown. Objectives To explore the mediation functional outcome by markers frailty (hereinafter frailty) patients ischemic stroke receiving endovascular thrombectomy (EVT). Design, Setting, and Participants This cohort study was post hoc analysis Safety...
Brain frailty impairs the ability to compensate for brain dysfunction and is linked worse outcomes after stroke. Stroke severity at presentation a key determinant of in acute ischemic This study aimed examine impact on initial stroke recovery (AIS) patients undergoing endovascular thrombectomy (EVT). We conducted post hoc analysis ESCAPE-NA1 randomized-controlled trial that investigated efficacy safety neuroprotectant nerinetide with AIS who received EVT. markers (cortical atrophy,...
<h3>Importance</h3> Some patients have poor outcomes despite small infarcts after endovascular therapy (EVT), while others with large do well. Understanding why these discrepancies occur may help to optimize EVT outcomes. <h3>Objective</h3> To validate exploratory findings from the Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion Emphasis on Minimizing CT Recanalization Times (ESCAPE) trial regarding pretreatment, treatment-related, posttreatment factors...
Incidental white matter hyperintensities (WMH) in Alzheimer's disease (AD) are usually attributed to small arterial occlusive disease. However, variability lesion change over time and unpredictable conditions between volumes cognition raise questions. An intraparenchymal venular disorder or CSF circulation disturbance perivascular spaces may need be considered explain non-lacunar focal WMH AD. Thirty-two AD (age=74) 10 healthy elderly(age=72) had two high resolution MRI at 1.3 years apart....
Studies of carotid endarterectomy (CEA) require stratification by symptomatic vs asymptomatic status because marked differences in benefits and harms. In administrative datasets, this classification has been done using hospital discharge diagnosis codes uncertain accuracy. This study aims to develop evaluate algorithms for classifying physician claims data.A single center's database was used assemble a retrospective cohort participants with CEA. Symptomatic ascertained chart review prior...
Objective: We wished to elucidate the patient experience of undergoing a lumbar puncture (LP) at teaching hospital identify elements that could be modified improve and integrate perspective into standardized LP curricula. Background: Although has been practiced for over 100 years, virtually no literature attends adults LP. Evidence suggests patients are apprehensive about this procedure. training curricula typically have not drawn from experience. Methods: performed qualitative study based...
Cytomegalovirus encephalitis may demonstrate unique MRI characteristics that allow for earlier diagnosis and treatment.
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The Montreal Cognitive Assessment (MoCA) more sensitively discriminates Mild Impairment (MCI) from normal aging than the Mini Mental Status Examination (MMSE). MoCA adds items testing visuospatial, executive, and milder memory dysfunction, but has yet to be validated against “gold standard” of conventional neuropsychological tests. How well it correlates with a global cognitive score co-occurring depressive symptoms also not been determined. 67 participants (normal control/NC = 21, MCI 12,...
Introduction: As image interpretation is a visual perception task, it affected by context and task structure. The non-contrast CT Alberta Stroke Program Early Score (ASPECTS) considered an objective radiologic measure of the extent ischemic change in cases acute stroke. We hypothesize that variability ASPECTS reading because readers are susceptible to interplay between higher-order, top-down information (clinical background or other imaging) bottom-up sensory information, experts more...
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