A5056260292- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Neurosurgical Procedures and Complications
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Meningioma and schwannoma management
- History of Medical Practice
- Trauma and Emergency Care Studies
- Surgical Simulation and Training
- Moyamoya disease diagnosis and treatment
- Anatomy and Medical Technology
- Cardiac Arrest and Resuscitation
- Aortic Disease and Treatment Approaches
- Neurofibromatosis and Schwannoma Cases
- Spinal Hematomas and Complications
- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Augmented Reality Applications
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Health and Disease Prevention
- Digital Imaging in Medicine
- Traumatic Brain Injury Research
University of Alberta Hospital
2010-2025
Health Sciences Centre
2019-2025
Alberta Hospital Edmonton
2010-2025
University of Alberta
2014-2024
Ottawa Hospital
2024
University of Ottawa
2024
Fondation Ophtalmologique Adolphe de Rothschild
2024
Centre Hospitalier de l’Université de Montréal
2024
Montreal Neurological Institute and Hospital
2019
Stanford University
2019
Background and Purpose— Patients harboring brain arteriovenous malformations (bAVMs) are at a lifelong risk for hemorrhagic strokes, but the natural history is poorly understood. We examined impact of demographic angiographic features on likelihood future hemorrhage. Methods— A prospectively accrued database bAVM patients maintained Toronto Western Hospital was analyzed; 678 consecutive, enrolled were followed 1931.7 patient-years. The rate hemorrhage over long-term follow-up recorded....
Flow diverting stents are emerging as a treatment option for difficult intracranial aneurysms. Current grading scales assessment of angiographic outcomes following aneurysm do not apply to aneurysms treated by flow diversion. We propose novel scale based on the degree filling and contrast stasis. This will facilitate communication standardize reporting diversion treatments.
<h3>BACKGROUND AND PURPOSE:</h3> Flow-diverting stents, such as the PED, have emerged a novel means of treating complex intracranial aneurysms. This retrospective analysis initial Canadian experience provides insight into technical challenges, clinical and radiographic outcomes, complication rates after use flow-diverting stents for unruptured <h3>MATERIALS METHODS:</h3> Cases were compiled from 7 centers between July 2008 December 2010. Each center prospectively tracked their experience;...
<h3>BACKGROUND AND PURPOSE:</h3> The PED is a flow-diverting stent designed for the treatment of cerebral aneurysms. We report 4 cases delayed ipsilateral IPH following technically successful anterior circulation aneurysms with PED. <h3>MATERIALS METHODS:</h3> Clinical and imaging data from all patients undergoing aneurysm at 2 institutions were analyzed to assess incidence after <h3>RESULTS:</h3> A total 66 (47 circulation) underwent between January 2008 November 2010. Four experienced...
Chronic shunt-dependent hydrocephalus is a recognized complication of aneurysmal subarachnoid hemorrhage. While its incidence and risk factors have been well described, the long-term performance shunts in this setting has not widely reported.Using administrative databases, authors derived retrospective cohort patients undergoing treatment ruptured aneurysm Ontario, Canada, between 1995 2005. The determined analyzed putative factors. Mortality rates indicators morbidity were recorded....
<h3>Background</h3> Unruptured intracranial aneurysms (UIAs) are increasingly diagnosed and commonly treated using endovascular treatment or microsurgical clipping. The safety efficacy of treatments have not been compared in a randomised trial. How to treat patients with UIAs suitable for both options remains unknown. <h3>Methods</h3> We randomly allocated clipping coiling one more 3–25 mm judged treatable ways. primary outcome was failure, defined as: initial failure aneurysm treatment,...
Spontaneous intracerebral hemorrhage is a particularly devastating type of stroke with greater morbidity and mortality compared ischemic can account for half or more all deaths from stroke. The seventh update the Canadian Stroke Best Practice Recommendations includes new stand-alone module on hemorrhage, focus elements care that are unique affect persons disproportionately relative to Prior this edition, was included in Acute Management limited its management during first 12 h. With growing...
<h3>BACKGROUND AND PURPOSE:</h3> Surgical clipping and endovascular treatment are commonly used in patients with unruptured intracranial aneurysms. We compared the safety efficacy of 2 treatments a randomized trial. <h3>MATERIALS METHODS:</h3> Clipping or were randomly allocated to one more 3- 25-mm aneurysms judged treatable both ways by participating physicians. The study hypothesized that would decrease incidence failure from 13% 4%, composite primary outcome defined as aneurysm...
<h3>BACKGROUND AND PURPOSE:</h3> The PED is an FDS designed for the treatment of intracranial aneurysms. Data regarding use this device in acute or subacute aSAH limited to a few case reports small series. We aimed demonstrate feasibility using FDS, PED, ruptured aneurysms with challenging morphologies. <h3>MATERIALS METHODS:</h3> conducted retrospective review all known patients treated at 4 institutions between June 2008 and January 2012. Pertinent clinical radiologic information was...
Complications of endovascular therapy aneurysms mainly include aneurysm rupture and thromboembolic events. The widespread use MR imaging for follow-up these patients revealed various nonvascular complications such as aseptic meningitis, hydrocephalus, perianeurysmal brain edema. We present 7 from 5 different institutions that developed imaging-enhancing lesions after aneurysms, detected a median time 63 days. number ranged 4-46 (median 10.5), sized 2-20 mm, were mostly in the same vascular...
<h3>SUMMARY:</h3> In this report, we present the fatal spontaneous delayed rupture of a previously unruptured large PICA aneurysm following treatment with PED. Pathology at postmortem examination has supported theory that intra-aneurysmal thrombus may acutely destabilize wall. Aneurysms an anatomic arrangement promote continued flow into neck not be optimal candidates for flow-diversion strategy.
Recurrence of chronic subdural haematomas (CSDHs) after surgical drainage is a significant problem with rates up to 20%. This study focuses on determining factors predictive haematoma recurrence and presents scoring system stratifying risk for individual patients.Between the years 2005 2009, 331 consecutive patients CSDHs treated surgery were included in this study. Univariate multivariate analyses performed searching increased post-operative volume requiring repeat drainage.We found 12%...
Background and Purpose- The purpose of this study was to assess recent trends in the admission mortality rates for subarachnoid hemorrhage Canada. Methods- This retrospective cross-sectional based on data retrieved from Canadian Institute Health Information all patients diagnosed with Canada between 2004 2015. Adjusted rate, in-hospital rates, discharge disposition were calculated. Results- A total 19 765 mean age 58.1 years, 40.3% men. annual hospitalization rate 6.34 per 100 000...
OBJECTIVE Treatment of wide-necked intracranial aneurysms is associated with higher recanalization and complication rates; however, the most commonly used methods are not specifically designed to work in bifurcation lesions. To address these issues, authors describe evolution design use eCLIPs (Endovascular Clip System) device, a novel hybrid stent-like assist device flow diverter properties that was first described 2008. METHODS A registry established covering 13 international centers at...
Many patients with ruptured intracranial aneurysms (RIAs) underrepresented or excluded from previous randomized controlled trials (RCTs) comparing surgery endovascular treatment (EVT) are still considered for surgical clipping, but the best management of these remains unknown. The International Subarachnoid Aneurysm Trial-2 was a trial versus EVT RIAs despite results RCTs, and also eligible EVT. primary endpoint death dependency according to modified Rankin Scale score (mRS > 2) at 1 year....
This study involved weekly radiographic examination of pinealectomized rats, hamsters, and chickens to observe the development scoliosis.To determine whether pinealectomy produces scoliosis in animals more closely related phylogenetically humans than chickens, namely rats which are representative mammals.Pinealectomy 3-day-old has consistently resulted with many characteristics similar those seen patients adolescent idiopathic scoliosis. It not been determined this phenomenon is restricted...
Object Enrolling a selected sample of ruptured intracranial aneurysms, the International Subarachnoid Aneurysm Trial (ISAT) found endovascular coiling to be superior microsurgical clipping. The performance in more general population aneurysms has not been adequately studied. Methods Using provincial administrative data from Ontario, authors conducted retrospective cohort study adult patients with subarachnoid hemorrhage (SAH) who underwent aneurysm repair. exposure was defined as versus...
The endoscopic technique is increasingly being used for the resection of pituitary adenomas. Its efficacy and safety have been generally accepted, but its impact on quality life patients treated has not previously addressed. Most studies assessing after long-term cure adenomas suggest a significantly impaired (QoL) in all subgroups tumours. In our study we analyse QoL data following surgery, attempt comparisons with normative from standard approaches. validated health questionnaire SF-36 was...
Flow diversion has become an established treatment option for challenging intracranial aneurysms. The use of small devices ≤3-mm diameter remains unapproved by major regulatory bodies. A retrospective review patients treated with Pipeline Embolization Devices at 3 Canadian institutions was conducted. Clinical and radiologic follow-up data were collected reported. Twelve cases ≥1 Device diameter, including 2 adjunctive coiling, a median 18 months (range, 4-42 months). One patient experienced...
<h3>BACKGROUND AND PURPOSE:</h3> Novel angiographic grading scales for the assessment of intracranial aneurysms treated with flow-diverting stents have been recently developed because previous cannot be applied to these aneurysms. The purpose this study was evaluate inter- and intraobserver variability novel O9Kelly Marotta scale, which specifically stents. <h3>MATERIALS METHODS:</h3> Multiple raters (<i>n</i> = 31) from disciplines neuroradiology neurosurgery were presented pre-...