A5074675567- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Spinal Cord Injury Research
- Medical Imaging and Analysis
- Spinal Dysraphism and Malformations
- Advanced Neuroimaging Techniques and Applications
- Cerebral Palsy and Movement Disorders
- Spinal Hematomas and Complications
- Trauma and Emergency Care Studies
- Scoliosis diagnosis and treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Brain Tumor Detection and Classification
- Nerve injury and regeneration
- Nerve Injury and Rehabilitation
- Pelvic and Acetabular Injuries
- Mesenchymal stem cell research
- Clinical practice guidelines implementation
- Digital literacy in education
- Online and Blended Learning
- Venous Thromboembolism Diagnosis and Management
- Medical Research and Treatments
- Bone and Joint Diseases
- Intracranial Aneurysms: Treatment and Complications
- Surgical Simulation and Training
Centre Hospitalier Universitaire de Rennes
2025
University of California, Davis
2021-2024
Neurological Surgery
2021-2024
University of California Davis Medical Center
2021-2024
University of Toronto
2011-2022
Toronto Western Hospital
2011-2021
University Health Network
2012-2021
Pacific Oaks College
2021
Krembil Brain Institute
2020
Oxford University Press (United Kingdom)
2020
In the e-permeated society, a society also increasingly unpredictable and uncertain, "digital literacy" becomes not only key factor in enabling participation education, as well employment other aspects of social life, but means gaining some understanding world. The DigEuLit project, funded by EC eLearning Initiative, has task defining digital literacy developing framework tools for development European educational settings. We have observed converging literacies which gained new relevance...
Guideline development.The objective of this study is to develop guidelines that outline how best manage (1) patients with mild, moderate, and severe myelopathy (2) nonmyelopathic evidence cord compression or without clinical symptoms radiculopathy.Five systematic reviews the literature were conducted synthesize on disease natural history; risk factors progression; efficacy, effectiveness, safety nonoperative surgical management; impact preoperative duration severity treatment outcomes;...
Acute spinal cord injury (SCI) is a traumatic event that results in disturbances to normal sensory, motor, or autonomic function and ultimately affects patient’s physical, psychological, social well-being. The management of patients with SCI has drastically evolved over the past century as result increasing knowledge on mechanisms, disease pathophysiology, role surgery. There still, however, remain controversial areas surrounding available strategies for treatment SCI, including use...
To develop recommendations on the timing of surgical decompression in patients with traumatic spinal cord injury (SCI) and central syndrome.A systematic review literature was conducted to address key relevant questions. A multidisciplinary guideline development group used this information, along their clinical expertise, for SCI syndrome. Based GRADE, a strong recommendation is worded as "we recommend," whereas weak presented suggest."Conclusions from included (1) isolated studies reported...
The objective of this guideline is to outline the appropriate use methylprednisolone sodium succinate (MPSS) in patients with acute spinal cord injury (SCI).A systematic review literature was conducted address key questions related MPSS SCI. A multidisciplinary Guideline Development Group used information, combination their clinical expertise, develop recommendations for MPSS. Based on GRADE (Grading Recommendation, Assessment, and Evaluation), a strong recommendation worded as "we...
Study Design Clinical practice guideline development following the GRADE process. Objectives Hemodynamic management is one of only available treatment options that likely improves neurologic outcomes in patients with acute traumatic spinal cord injury (SCI). Augmenting mean arterial pressure (MAP) aims to improve blood perfusion and oxygen delivery injured order minimize secondary ischemic damage neural tissue. The objective this was update 2013 AANS/CNS recommendations on hemodynamic SCI,...
Study Design Clinical practice guideline development. Objectives Acute spinal cord injury (SCI) can result in devastating motor, sensory, and autonomic impairment; loss of independence; reduced quality life. Preclinical evidence suggests that early decompression the may help to limit secondary injury, reduce damage neural tissue, improve functional outcomes. Emerging indicates “early” surgical completed within 24 hours also improves neurological recovery patients with acute SCI. The...
<ns4:p>Traumatic spinal cord injuries (SCIs) affect 1.3 million North Americans, producing devastating physical, social, and vocational impairment. Pathophysiologically, the initial mechanical trauma is followed by a significant secondary injury which includes local ischemia, pro-apoptotic signaling, release of cytotoxic factors, inflammatory cell infiltration. Expedient delivery medical surgical care during this critical period can improve long-term functional outcomes, engendering concept...
Narrative review.To discuss the current understanding of natural history degenerative cervical myelopathy (DCM).Literature review summarizing evidence pertaining to and risk factors DCM.DCM is a common condition in which progressive arthritic disease spine leads spinal cord compression resulting constellation neurological symptoms, particular upper extremity dysfunction gait impairment. Anatomical including cord-canal mismatch, congenitally fused vertebrae genetic may increase individuals'...
Literature Review (Narrative).
Study design Systematic review and meta-analysis. Objective Surgical decompression is a cornerstone in the management of patients with traumatic spinal cord injury (SCI); however, influence timing surgery on neurological recovery after acute SCI remains controversial. This systematic aims to summarize current evidence effectiveness, safety, cost-effectiveness early (≤24 hours) or late (>24 for all levels spine. Furthermore, this evaluate respect impact ultra-early (earlier than 24 hours...
Study Design Development of a clinical practice guideline following the Grading Recommendations, Assessment, and Evaluation (GRADE) process. Objective The objectives this study were to develop guidelines that outline utility intraoperative neuromonitoring (IONM) detect spinal cord injury (ISCI) among patients undergoing spine surgery, define subset surgery at higher risk for ISCI protocols prevent, diagnose, manage ISCI. Methods All systematic reviews performed according PRISMA standards...
Systematic review update.
The patterns of length alterations in the hand bones cases pseudohypoparathyroidism (PHP), pseudopseudohypoparathyroidism (PPHP), and acrodysostosis were evaluated. each was measured compared to appropriate means for age sex. pattern profiles thus generated showed that those PHP PPHP are almost identical, similar seen acrodysostosis, except much smaller size latter condition. probably different manifestations same entity, may also be related them. Brachydactyly E is indistinguishable...
The Pipeline Embolization Device (PED) is a flow-diverting stent that may represent new therapeutic tool for difficult-to-treat intracranial aneurysms, including those present with subarachnoid hemorrhage (SAH).To demonstrate the feasibility of utilizing PED as primary treatment ruptured aneurysms challenging morphologies.Three patients presented SAH. Three distinct and aneurysm morphologies were encountered: (1) small basilar trunk pseudoaneurysm, (2) carotid artery blister aneurysm, (3) an...
<h3>BACKGROUND AND PURPOSE:</h3> The PED is an FDS designed for the treatment of intracranial aneurysms. Data regarding use this device in acute or subacute aSAH limited to a few case reports small series. We aimed demonstrate feasibility using FDS, PED, ruptured aneurysms with challenging morphologies. <h3>MATERIALS METHODS:</h3> conducted retrospective review all known patients treated at 4 institutions between June 2008 and January 2012. Pertinent clinical radiologic information was...
<h3>BACKGROUND AND PURPOSE:</h3> T2*-weighted imaging provides sharp contrast between spinal cord GM and WM, allowing their segmentation cross-sectional area measurement. Injured WM demonstrates T2*WI hyperintensity but requires normalization for quantitative use. We introduce WM/GM signal-intensity ratio compare it against area, the DTI metric fractional anisotropy, magnetization transfer in degenerative cervical myelopathy. <h3>MATERIALS METHODS:</h3> Fifty-eight patients with myelopathy...