A5100459906- Hepatitis B Virus Studies
- Heat shock proteins research
- Immunotherapy and Immune Responses
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Liver Disease Diagnosis and Treatment
- Natural product bioactivities and synthesis
- Virus-based gene therapy research
- Cancer-related molecular mechanisms research
- Pediatric health and respiratory diseases
- Hepatitis C virus research
- Medicinal Plants and Bioactive Compounds
- Galectins and Cancer Biology
- Organ Transplantation Techniques and Outcomes
- Stress Responses and Cortisol
- RNA Interference and Gene Delivery
- Tryptophan and brain disorders
- Immune Cell Function and Interaction
- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- ATP Synthase and ATPases Research
- Cardiovascular Health and Disease Prevention
- Lung Cancer Diagnosis and Treatment
- Scoliosis diagnosis and treatment
- Winter Sports Injuries and Performance
- Gastric Cancer Management and Outcomes
Zhejiang University
2025
Sir Run Run Shaw Hospital
2025
Hebei Medical University
2018-2024
Second Hospital of Hebei Medical University
2018-2024
Xizang Minzu University
2021-2024
Second Xiangya Hospital of Central South University
2024
Central South University
2024
Shaanxi University of Chinese Medicine
2013-2023
Gansu Provincial Hospital
2023
North China University of Science and Technology Affiliated Hospital
2023
Interstitial lung disease (ILD) is a relatively common extraarticular manifestation of rheumatoid arthritis (RA) that contributes significantly to burden and excess mortality. The purpose this study was identify peripheral blood markers RA-associated ILD can facilitate earlier diagnosis provide insight regarding the pathogenesis potentially devastating complication.Patients with RA who were enrolled in well-characterized Chinese identification cohort or US replication subclassified as having...
Salidroside inhibited the proliferation of cancer cell. Nevertheless, mechanism has not been completely clarified. The purpose study is to explore mechanisms salidroside against gastric cancer. To analyze changes microRNA (miRNA) in cells under treatment salidroside, miRNA expression was analyzed by using RNA-seq for 24 h after treatment. differentially expressed miRNAs were clustered and their target genes analyzed. Selected mRNA further verified q-PCR. expressions detected...
Objective and background: Increasing evidence suggests that low‐dose theophylline has anti‐inflammatory benefits is safe in the treatment of COPD. This study aims to evaluate efficacy safety low‐dose, slow‐release oral administered over a 1‐year period patients with Methods: A randomized, double‐blind, parallel‐group, placebo‐controlled trial was carried out. In total, 110 participants COPD were randomly assigned receive (100 mg b.i.d.) or placebo for 1 year. Use medicine symptoms recorded...
Curcumin, a derivative from the dried rhizome of <italic>curcuma longa</italic>, has been proven to possess anti-tumor effects.
Background: Greater adiposity is associated with higher blood pressure. Substantial uncertainty remains, however, about which measures of most strongly predict pressure and whether these associations differ materially between populations. Methods: We examined cross-sectional data on 500 000 adults recruited from 10 diverse localities across China during 2004–08. Multiple linear regression was used to estimate the effects systolic (SBP) general [e.g. body mass index (BMI), fat percentage,...
Thickened skin is a major clinical feature in patients with systemic sclerosis (SSc). We investigated changes of thickness SSc using both high frequency ultrasound (HFU) and the modified Rodnan score (mRSS) to evaluate feasibility application HFU involvement relationship between profiles. recruited 31 consecutive age-matched sex-matched healthy controls this prospective, cross-sectional study. Skin was measured by an 18-MHz ultrasonic probe at five different sites. Total (TST) categorical...
Objectives Vascular access thrombosis (VAT) is a common complication in patients with end-stage renal disease (ESRD), significantly impacting hemodialysis efficacy and patient survival. Currently, temporary dialysis typically established via deep vein catheterization (VC), however, this method highly invasive associated risks of infection other complications. This study aims to explore the feasibility using direct anastomosis indwelling needle puncture (DAINP) for access.
Protein phosphatase 2A (PP2A) is a tumor suppressor whose function lost in many cancers. An emerging, though counterintuitive, therapeutic approach inhibition of PP2A to drive damaged cells through the cell cycle, sensitizing them radiotherapy. We investigated effects on U251 glioblastoma following radiation treatment vitro and xenograft mouse model vivo. Radiotherapy alone augmented activity, this was significantly attenuated with combination LB100 treatment. yielded dose enhancement factor...
This study involved weekly radiographic examination of pinealectomized rats, hamsters, and chickens to observe the development scoliosis.To determine whether pinealectomy produces scoliosis in animals more closely related phylogenetically humans than chickens, namely rats which are representative mammals.Pinealectomy 3-day-old has consistently resulted with many characteristics similar those seen patients adolescent idiopathic scoliosis. It not been determined this phenomenon is restricted...
Extrathymic CD4+CD8+ double-positive (DP) T cells are increased in some pathophysiological conditions, including infectious diseases. In the murine model of Chagas disease, it has been shown that protozoan parasite Trypanosoma cruzi is able to target thymus and induce alterations thymic microenvironment lymphoid compartment. acute phase, this results a severe atrophy organ early release DP into periphery. To date, effect changes promoted by infection on central tolerance remained elusive....
Objective The efficacy of sirolimus in treating severe or refractory systemic lupus erythematosus (SLE) has been confirmed by small-scale clinical trials. However, few studies focused on mild moderate SLE. Therefore, this study we elucidated add-on patients with Methods Data 17 consecutive SLE were retrospectively collected. Disease Activity Index-2000 (SLEDAI-2K), manifestation, laboratory data and peripheral T lymphocyte subsets cytokines collected before 6 months after treatment. cell...
Abstract Background Previous studies have demonstrated a strong association between depression and job burnout among healthcare professionals, but the results been inconsistent, there is lack of in-depth exploration such relationship different professions. The present study aims to investigate interrelationships Chinese professionals whether are differences in networks these symptoms doctors nurses. Methods Maslach Burnout Inventory-General Survey 2-item Patient Health Questionnaire were...
The mechanism underlying the development of scoliosis after pinealectomy in young chickens is unknown. However, since main product pineal gland melatonin, melatonin remains an obvious focus studies designed to discover this mechanism. One confounding factor that serum levels are close zero but does not develop all have had procedure. Therefore, role controversial.In current investigation, two pilot demonstrated a physiological therapeutic dose (2.5 milligrams per kilogram body weight)...
// Rong Fu 1, * , Yan Chen Xiao-Ping Wang 1 Teng An Lei Tao Yu-Xin Zhou Yu-Jie Huang Bao-An 2 Zhi-Yu Li 3 Qi-Dong You 4 Qing-Long Guo Zhao-Qiu Wu Department of Physiology, State Key Laboratory Natural Medicines and Jiangsu Carcinogenesis Intervention, China Pharmaceutical University, Nanjing 210009, Hematology Oncology, Zhongda Hospital, Medical School, Southeast 211189, Medicinal Chemistry, Drug Design Optimization, These authors have contributed equally to this work Correspondence to: Guo,...
// Anli Yang 1, * , Weiqiang Ju Xiaopeng Yuan Ming Han 1 Xiaoping Wang Zhiyong Guo Xiaoli Wei 2 Dongping Xiaofeng Zhu Linwei Wu and Xiaoshun He Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China Department Medical Oncology, University Cancer State Key Laboratory Oncology in South China, Collaborative Innovation Center for Medicine, 510060, These authors have contributed equally to this work Correspondence to: Wu, email: lw97002@163.com...