Lingzhi Hu

ORCID: 0000-0001-5355-3803
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About
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Research Areas
  • Medical Imaging Techniques and Applications
  • Advanced MRI Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced Radiotherapy Techniques
  • Atomic and Subatomic Physics Research
  • Photochemistry and Electron Transfer Studies
  • Nonlinear Optical Materials Studies
  • MRI in cancer diagnosis
  • Lung Cancer Diagnosis and Treatment
  • Radiation Detection and Scintillator Technologies
  • Cardiac Imaging and Diagnostics
  • Porphyrin and Phthalocyanine Chemistry
  • Renal cell carcinoma treatment
  • Photonic and Optical Devices
  • Brain Tumor Detection and Classification
  • Face and Expression Recognition
  • China's Socioeconomic Reforms and Governance
  • Laser-Matter Interactions and Applications
  • Ombudsman and Human Rights
  • Advanced Clustering Algorithms Research
  • Advanced Computing and Algorithms
  • Wireless Sensor Networks and IoT
  • Retinal and Optic Conditions
  • Microwave Imaging and Scattering Analysis
  • Economic Development and Digital Transformation

United Imaging Healthcare (China)
2019-2024

Shanxi Medical University
2024

Nanjing Agricultural University
2023

Anhui University
2022

Shaanxi University of Chinese Medicine
2006-2021

University of America
2019-2021

University of Science and Technology of China
2021

Jiangxi College of Applied Technology
2021

Highland Community College - Illinois
2014-2016

Philips (United States)
2014-2016

The collaboration of Yale, the University California, Davis, and United Imaging Healthcare has successfully developed NeuroEXPLORER, a dedicated human brain PET imager with high spatial resolution, sensitivity, built-in 3-dimensional camera for markerless continuous motion tracking. It depth-of-interaction time-of-flight resolutions, along 52.4-cm transverse field view (FOV) an extended axial FOV (49.5 cm) to enhance sensitivity. Here, we present physical characterization, performance...

10.2967/jnumed.124.267767 article EN cc-by Journal of Nuclear Medicine 2024-06-13

The classical maximum entropy clustering (MEC) algorithm usually cannot achieve satisfactory results in the situations where data is insufficient, incomplete, or distorted. To address this problem, inspired by transfer learning, specific cluster prototypes and fuzzy memberships jointly leveraged (CPM-JL) framework for cross-domain MEC (CDMEC) firstly devised paper, then corresponding referred to as CPM-JL-CDMEC dedicated validity index named memberships-based difference measurement (FM-CDDM)...

10.1109/tcyb.2015.2399351 article EN IEEE Transactions on Cybernetics 2015-02-24

Purpose: MR‐based pseudo‐CT has an important role in radiation therapy planning and PET attenuation correction. The purpose of this study is to establish a clinically feasible approach, including image acquisition, correction, CT formation, for generation the brain using single‐acquisition, undersampled ultrashort echo time (UTE)‐mDixon pulse sequence. Methods: Nine patients were recruited study. For each patient, 190‐s, undersampled, single acquisition UTE‐mDixon sequence was acquired (TE =...

10.1118/1.4926756 article EN Medical Physics 2015-07-31

The existing, semisupervised, spectral clustering approaches have two major drawbacks, i.e., either they cannot cope with multiple categories of supervision or sometimes exhibit unstable effectiveness. To address these issues, normalized affinity and penalty jointly constrained frameworks as well their corresponding algorithms, referred to type-I (TI-APJCSC) type-II (TII-APJCSC), respectively, are proposed in this paper. TI refers TII type-II. significance paper is fourfold. First,...

10.1109/tnnls.2015.2511179 article EN IEEE Transactions on Neural Networks and Learning Systems 2016-02-18

In this work, a GPU-accelerated fully 3D ordered-subset expectation maximization (OSEM) image reconstruction with point spread function (PSF) modeling was developed for small animal PET scanner long axial field of view (FOV). Dual-ended readout detectors that provided high depth interaction (DOI) resolution were used the to simultaneously achieve uniform spatial and sensitivity. First, we novel sinogram generation method, in which dimension determined first then an event assigned few...

10.1088/1361-6560/aba6f9 article EN Physics in Medicine and Biology 2020-07-17

Head motion correction (MC) is an essential process in brain positron emission tomography (PET) imaging. We have used the Polaris Vicra, optical hardware-based tracking (HMT) device, for PET head MC. However, this requires attachment of a marker to subject's head. Markerless HMT (MLMT) methods are more convenient clinical translation than with external markers. In study, we validated United Imaging Healthcare (UMT) MLMT system using phantom and human point source studies, tested its...

10.1088/1361-6560/ad0e37 article EN cc-by Physics in Medicine and Biology 2023-11-20

The aim of this study was to validate quantitative performance a newly released simultaneous positron emission tomography (PET)/magnetic resonance imaging (MRI) scanner, by using MR-based attenuation correction (MRAC), both in phantom and patient study. PET/MRI image uniformities under different hardware configurations were tested compared. Thirty patients examined with 2-deoxy-2-[ 18 F]fluoro-D-glucose ( F-FDG) PET/computed (CT) subsequent PET/MRI. PET images from corrected MRAC (PET MR ),...

10.1155/2019/8213215 article EN cc-by BioMed Research International 2019-11-28

Purpose: The ultrashort echo‐time (UTE) sequence is a promising MR pulse for imaging cortical bone which otherwise difficult to image using conventional sequences and also poses strong attenuation photons in radiation therapy PET imaging. authors report here systematic characterization of signal decay scanning time optimization strategy the UTE through k ‐space undersampling, can result up 75% reduction acquisition time. Using undersampled sequence, attempted quantitatively investigate...

10.1118/1.4894709 article EN Medical Physics 2014-09-20

Abstract Background Integrated whole-body PET/MR technology continues to mature and is now extensively used in clinical settings. However, due the special design architecture, integrated comes with a few inherent limitations. Firstly, lacks sensitivity resolution for focused organs. Secondly, broader access of has been significantly restricted its prohibitively high cost. The MR-compatible PET insert an independent removable scanner which can be placed within MRI bore. mobility...

10.1186/s40658-021-00392-5 article EN cc-by EJNMMI Physics 2021-06-12

We aimed to investigate the effectiveness of endovascular therapy (EVT) versus intravenous thrombolysis (IVT) in patients with basilar artery occlusion (BAO), based on information advanced imaging.We analyzed data stroke radiologically confirmed BAO within 24 hours. subjects were categorized into "top-of-the-basilar" syndrome (TOBS) and other types. An initial infarct size <70ml a ratio ischemic tissue volume ≥1.8 was defined as "target mismatch." The primary outcome good outcome, modified...

10.1002/ana.26376 article EN cc-by-nc-nd Annals of Neurology 2022-04-19

Abstract Purpose To systematically evaluate the consistency of various standardized uptake value (SUV) lean body mass (LBM) normalization methods in a clinical positron emission tomography/magnetic resonance imaging (PET/MR) setting. Methods SUV brain, liver, prostate, parotid, blood, and muscle were measured 90 18 F-FDG 28 F-PSMA PET/MR scans corrected for LBM using James, Janma (short Janmahasatian), Dixon approaches. The prospective study was performed from December 2018 to August 2020 at...

10.1186/s40658-021-00363-w article EN cc-by EJNMMI Physics 2021-02-17

Abstract The purpose of this work was to develop and evaluate a deep learning approach for automatic rat brain image segmentation magnetic resonance imaging (MRI) images in clinical PET/MR, providing useful tool analyzing studies the pathology progression neurological disease validate new radiotracers therapeutic agents. Rat PET/MR ( N = 56) were collected from system using dedicated small-animal phased array coil. A method based on triple cascaded convolutional neural network (CNN)...

10.1088/1361-6560/abd2c5 article EN cc-by Physics in Medicine and Biology 2021-02-01

We report a new series of organic systems for photon-gated photochemical hole burning by donor–acceptor electron transfer at 4.2 K. The donor molecules (RZT) are meso-tetraaryl derivatives zinc-tetrabenzoporphyrin: the aryls phenyl (PZT), p-tolyl (TZT), and α-naphthayl (NZT), respectively. acceptor can be one several aromatic cyanides (AC's), e.g., dicyanobenzene, cyanonaphthalene, or cyanoanthracene. These have an inhomogeneously broadened optical transition centered 627 nm with FWHM that...

10.1364/josab.9.000800 article EN Journal of the Optical Society of America B 1992-05-01

The current work was based on a previously developed 4D image reconstruction method for myocardial perfusion (MP) PET where dual respiratory motion (RM) and cardiac (CM) compensation were performed post reconstruction. We implemented extended the patient data from commercial system demonstrated further quality improvement. divided events into 6 equal-count gates heart "center-of-mass" movement estimated list-mode data. For each gate, sorted rebinned 8 16 in addition to conventional gates....

10.1109/nssmic.2014.7430789 article EN 2021 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) 2014-11-01

Abdominal MRI is susceptible to respiratory motion artifacts. The existing clinical solution using breathing belt track the movement of abdomen and trigger acquisition during end-expiration phase. Attaching patients often slows down workflow affects patient comfort especially for those with surgical wounds disorders. Herein we, first, propose a novel compatible frequency modulated continuous wave (FMCW) radar within bore in non-contact fashion. electromagnetic from FMCW can penetrate...

10.1117/12.2582141 article EN Medical Imaging 2018: Physics of Medical Imaging 2021-02-13
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