A5069220167- Acute Ischemic Stroke Management
- Cerebral Venous Sinus Thrombosis
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Blood Coagulation and Thrombosis Mechanisms
- Heparin-Induced Thrombocytopenia and Thrombosis
- Stroke Rehabilitation and Recovery
- Long-Term Effects of COVID-19
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological and metabolic disorders
- Eicosanoids and Hypertension Pharmacology
- Foreign Body Medical Cases
- Preterm Birth and Chorioamnionitis
- COVID-19 and healthcare impacts
- Renin-Angiotensin System Studies
- Cerebrospinal fluid and hydrocephalus
- Mollusks and Parasites Studies
- Autopsy Techniques and Outcomes
- Hemoglobinopathies and Related Disorders
- Retinal and Optic Conditions
- Cerebrovascular and Carotid Artery Diseases
- Inflammatory Biomarkers in Disease Prognosis
- Alcoholism and Thiamine Deficiency
- Chronic Myeloid Leukemia Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
Hospital de Santa Maria
2016-2023
University of Lisbon
2020-2023
University of Thessaly
2022
Boston University
2022
Boston Medical Center
2022
Centro Hospitalar Lisboa Norte
2016-2022
Hospital de Egas Moniz
2022
Background and Purpose— The hypothesis that venous recanalization prevents progression of infarction is not established in patients with cerebral thrombosis (CVT). Evidence also scarce on the association between residual symptoms, particularly headache, grade. We aimed to assess, CVT treated standard anticoagulation, (1) rate early recanalization, (2) whether lack was predictor parenchymal brain lesion progression, (3) prevalence features persistent headache according grade achieved....
<h3>Background and Objectives</h3> COVID-19–related inflammation, endothelial dysfunction, coagulopathy may increase the bleeding risk lower efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate safety outcomes AIS COVID-19. <h3>Methods</h3> This was a retrospective multicenter cohort study consecutive receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 June 2021 tested for severe respiratory...
Experimental studies suggest inflammation can contribute to blood barrier disruption and brain injury in cerebral venous thrombosis (CVT). We aimed determine whether biomarkers of were associated with the evolution lesions, persistent occlusion or functional outcome patients CVT.Pathophysiology Venous Infarction-Prediction Infarction Recanalization CVT (PRIORITy-CVT) was a multicenter prospective cohort study newly diagnosed CVT. Evaluation neutrophil-to-lymphocyte ratio (NLR) C-reactive...
Cerebral venous thrombosis (CVT) due to vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe condition, with high in-hospital mortality rates. Here, we report clinical outcomes of patients CVT-VITT after SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) vaccination who survived initial hospitalization.We used data from an international registry developed CVT within 28 days vaccination, collected until February 10, 2022. VITT diagnosis was classified based on the...
Background Headache in ischemic stroke survivors after the acute stage is incompletely described. Objective We aimed to prospectively describe characteristics of headache and predictors at chronic stroke. Methods conducted a prospective observational cohort study including 102 patients admitted Stroke Unit. Patients were interviewed (12 months stroke). Characteristics those headaches collected using previously validated questionnaire enabling classification following International Society...
Abstract Background Elucidating mechanisms of brain damage in cerebral venous thrombosis (CVT) would be instrumental to develop targeted therapies and improve prognosis prediction. Matrix metalloproteinase-9 (MMP-9), a gelatinase that degrades major components the basal lamina, has been associated blood–brain barrier disruption. We aimed assess, patients with CVT, temporal change serum concentrations MMP-9 its association key imaging clinical outcomes. Methods Pathophysiology Venous...
Spontaneous blood pressure drop within the first 24 h has been reported following arterial recanalisation in ischaemic stroke patients. We aimed to assess if spontaneous hour after mechanical thrombectomy is a marker of early neurological recovery.Retrospective observational single-centre study including patients treated with thrombectomy. Blood parameters from admission, start, end and hourly were reviewed. Primary outcome was dramatic recovery (8-point-reduction NIHSS or ≤ 2 at h)....
Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing are not equally distributed within country, which may lead to differential access treatment. Our main aim was perform a descriptive analysis metrics regarding in mainland its administrative districts.A retrospective national multicentric cohort study conducted, including all ischemic patients treated with over two years (July 2015...
A 78-year-old man presented to the emergency department with weakness on left side. Fifty-four minutes after initiation of intravenous tissue plasminogen activator, swelling developed side tongue, a finding that was consistent angioedema.
We report two cases of cerebral venous thrombosis associated with the use compounded preparations containing several active substances prescribed for weight loss. In both there is suspicion additive/synergic interaction oral contraceptives. The adverse drug reactions were considered serious, being life-threatening and causing hospitalisation days.