Ludovica Migliaccio
- Venous Thromboembolism Diagnosis and Management
- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Long-Term Effects of COVID-19
- Diagnosis and Treatment of Venous Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- COVID-19 and healthcare impacts
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular Syncope and Autonomic Disorders
- Central Venous Catheters and Hemodialysis
- Takotsubo Cardiomyopathy and Associated Phenomena
- Neurological and metabolic disorders
- Antiplatelet Therapy and Cardiovascular Diseases
- Retinal and Optic Conditions
- Cardiac Arrhythmias and Treatments
- Climate Change and Health Impacts
- Stroke Rehabilitation and Recovery
- Cerebral Venous Sinus Thrombosis
- Cardiac Valve Diseases and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Epilepsy research and treatment
- Cerebrospinal fluid and hydrocephalus
- Musculoskeletal synovial abnormalities and treatments
- Intramuscular injections and effects
Istituto delle Scienze Neurologiche di Bologna
2020-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2024
Ospedale Maggiore
2022-2023
Ospedale Maggiore Carlo Alberto Pizzardi
2023
University of Lausanne
2023
Helsinki University Hospital
2023
University Hospital of Bern
2023
University of Zurich
2023
University of Helsinki
2023
Hospital de Egas Moniz
2022
<h3>Background and Objectives</h3> COVID-19–related inflammation, endothelial dysfunction, coagulopathy may increase the bleeding risk lower efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate safety outcomes AIS COVID-19. <h3>Methods</h3> This was a retrospective multicenter cohort study consecutive receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 June 2021 tested for severe respiratory...
Vitamin K antagonists (VKA) are the most widely used anticoagulants in world. An appropriate management of treated patients is crucial for their efficacy and safety. The prospective, observational, multicenter, inception-cohort FCSA-START Register, a branch START Register (NCT02219984) included VKA-treated managed by centers Italian Federation anticoagulation clinics (AC). Baseline patient characteristics data during treatment were analyzed compared with those ISCOAT study, performed...
Background Thrombocytopenia is associated with increased mortality in the general population, but few data exist patients atrial fibrillation ( AF ) taking oral anticoagulants. We investigated factor determinants of thrombocytopenia a large cohort affected by and its association total mortality. Methods Results Multicenter prospective study, including 5215 from START (Survey on Anticoagulated Patients Register) registry, 3877 (74.3%) 1338 (25.7%) vitamin K or non–vitamin antagonist...
Background: Symptomatic intracerebral hemorrhage (sICH) and major bleeding can be fatal complications of intravenous thrombolysis (IVT) for acute ischemic stroke. We investigated the impact early fibrinogen depletion after IVT on events. Methods: This multicenter observational prospective cohort study enrolled 1678 consecutive patients receiving stroke at 6 Italian centers, undergoing concentration assessment baseline, 2 hours IVT. Fibrinogen was defined as a reduction below 200 mg/dL from...
Abstract Introduction A reduction of the hospitalization and reperfusion treatments was reported during COVID-19 pandemic. However, high variability in results emerged, potentially due to logistic paradigms adopted. Here, we analyze stroke code admissions, hospitalizations, belt performance for ischemic patients metropolitan Bologna region, comparing temporal trends between 2019 2020 define impact on network. Methods This retrospective observational study included all people admitted at...
Direct oral anticoagulants (DOACs) have shown similar efficacy and safety with respect to warfarin in patients atrial fibrillation (AF). However, the proportion of aged ≥85 years enrolled clinical trials was low applicability their results very elderly is still uncertain. We carried out a prospective cohort study on AF Survey anticoagulaTed pAtients RegisTer (START2-Register) treated either VKAs or DOACs, aim evaluate mortality, bleeding thrombotic rates during long-term follow-up. 1124 who...
The association of COVID-19 with higher bleeding risk and worse outcomes in acute ischemic stroke (AIS) undergoing revascularization may be related to the presence infection symptoms. We aimed assess safety treatments patients AIS asymptomatic (AS-COVID) or symptomatic (S-COVID).
Whole-Arm Ultrasound to Rule Out Suspected Upper-Extremity Deep Venous Thrombosis in OutpatientsUpper-extremity deep venous thrombosis (UE-DVT) accounts for approximately 14% of all cases DVT. 1 Because UE-DVT may provoke pulmonary embolism (PE), prompt diagnosis is necessary select the patients who require anticoagulation.This study aimed evaluate failure rate ultrasonographic screening UE-DVT. Methods | Study Design.A prospective management was conducted from January 1, 2011, through...
Patients with venous thromboembolism (VTE) should receive a decision on the duration of anticoagulant treatment (AT) that is often not easy to make. Sixteen Italian clinical centers included patients recent VTE in START2-POST-VTE register and reported decisions taken AT each patient reasons for them. At moment this report, 472 (66.9%) 705 registry were told stop 59.3% extend it 40.7% patients. Anticoagulant lasted ≥3 months >90% was extended proximal deep vein thrombosis because...
Background Exertional dyspnea is a frequently encountered complaint in clinical practice. However, the prevalence of pulmonary embolism (PE) among patients with on exertion has not been reported. Objective The objective this study was to assess objectively confirmed PE consecutive visiting an emergency department because recent onset exertional dyspnea. Methods Patients aged ≤75 years (<1 month) marked had systematic workup for PE, irrespective concomitant signs or symptoms venous...
IV thrombolysis (IVT) for suspected ischemic stroke in patients with intracranial neoplasms is off-label. However, data on risks of hemorrhage (ICH) are scarce.
Randomised control trials have assessed the efficacy and safety of direct oral anticoagulants in prophylaxis treatment venous thromboembolism (VTE). Positive but limited results been reported patients with inherited thrombophilia. Using an Italian, multicentre, prospective registry consecutive presenting symptomatic, acute VTE, we aimed to assess which factors are involved making choice drug that best fits patient's risk profile a large real-world setting VTE patients.We investigated 4,866...