A5042766479- Acute Ischemic Stroke Management
- Epilepsy research and treatment
- Cerebrovascular and Carotid Artery Diseases
- Chronic Myeloid Leukemia Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Chronic Lymphocytic Leukemia Research
- Cerebral Venous Sinus Thrombosis
- Neurosurgical Procedures and Complications
- EEG and Brain-Computer Interfaces
- Neurological Complications and Syndromes
- Atrial Fibrillation Management and Outcomes
- Ophthalmology and Eye Disorders
- Migraine and Headache Studies
- Neonatal and fetal brain pathology
- Pharmacological Effects and Toxicity Studies
- Cerebrospinal fluid and hydrocephalus
- Vasculitis and related conditions
- Eosinophilic Disorders and Syndromes
- Acute Myeloid Leukemia Research
- Neuroscience and Neuropharmacology Research
- Lymphoma Diagnosis and Treatment
Hospital de Santa Maria
2016-2025
University of Lisbon
2015-2025
Universidade Federal de Santa Maria
2024
Centro Hospitalar Lisboa Norte
2013-2024
Hospital de Egas Moniz
2019-2022
University of Thessaly
2022
Boston University
2022
Boston Medical Center
2022
National Legal Medicine Institute
2021
Instituto de Medicina Molecular João Lobo Antunes
2021
Importance Acute symptomatic seizures occurring within 7 days after ischemic stroke may be associated with an increased mortality and risk of epilepsy. It is unknown whether the type acute seizure influences this risk. Objective To compare epilepsy following different types seizures. Design, Setting, Participants This cohort study analyzed data acquired from 2002 to 2019 9 tertiary referral centers. The derivation included adults cohorts 2 case-control studies neuroimaging-confirmed without...
Ischemic stroke is a leading cause of disability and death worldwide among adults. The individual prognosis after extremely dependent on treatment decisions physicians take during the acute phase. In last five years, several scores such as ASTRAL, DRAGON, THRIVE have been proposed tools to help predict patient functional outcome stroke. These are rule-based classifiers that use features available when admitted emergency room. this paper, we apply machine learning techniques problem...
Objective The purpose of this study was to identify risk factors for acute symptomatic seizures and post‐stroke epilepsy after ischemic stroke evaluate the effects reperfusion treatment. Methods We assessed using logistic or Cox regression in a multicenter study, including adults from 8 European referral centers with neuroimaging‐confirmed stroke. compared between participants without treatment following propensity score matching reduce confounding due selection. Results In overall cohort...
Background and Purpose Interobserver reliability of the diagnosis transient ischemic attack (TIA) is low, TIA made by nonneurologists often erroneous. We sought to validate general practitioners (GPs) hospital emergency service physicians (emergency MDs). Methods A list 20 neurological symptoms was distributed GPs 22 neurologists who graded compatibility each symptom with diagnosis. At least two validated diagnoses for patients under their care or MDs. Results Compared neurologists,...
Background and Purpose— The efficacy of the antiplatelet agent triflusal for prevention vascular events after stroke has been reported in a pilot study. However, there is need to confirm those results larger Methods— We performed randomized, double-blind, multicenter study test (600 mg/d) versus aspirin (325 patients with or transient ischemic attack (Triflusal Aspirin Cerebral Infarction Prevention [TACIP]). assessed combined end point (incidence nonfatal stroke, acute myocardial...
Electroencephalography (EEG) can identify biomarkers of epileptogenesis and ictogenesis. However, few studies have used EEG in the prediction poststroke seizures. Our primary aim was to evaluate whether early abnormalities predict epilepsy.
A case control study of transient global amnesia (TGA), ischaemic attacks (TIA) and normal controls is described. Each the 51 TGA patients, selected between January 1985 March 1990, was compared with four (two TIAs two normals) for presence vascular risk factors (hypertension, diabetes, smoking habits, cholesterol, triglycerides haematocrit levels, heart disease, previous stroke), TGA, migraine, psychiatric illness recent head trauma. Patients had less hypercholesterolaemia...
<h3>Background:</h3> Patients with concomitant diabetes mellitus (DM) and prior stroke (PS) were excluded from European approval of alteplase in stroke. We examined the influence DM PS on outcomes patients who received thrombolytic therapy (T; data Safe Implementation Thrombolysis Stroke–International Stroke Register) compared to nonthrombolyzed controls (C; Virtual International Trials Archive). <h3>Methods:</h3> selected ischemic whom we held age, baseline NIH Scale score (NIHSS), 90-day...
<h3>Background and Objectives</h3> COVID-19–related inflammation, endothelial dysfunction, coagulopathy may increase the bleeding risk lower efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate safety outcomes AIS COVID-19. <h3>Methods</h3> This was a retrospective multicenter cohort study consecutive receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 June 2021 tested for severe respiratory...
Background and Purpose —The first medical contact of an acute stroke victim is often a nonneurologist. Validation diagnosis made by these doctors poorly known. The present study seeks to validate the diagnoses general practitioners (GPs) hospital emergency service physicians (ESPs). Methods —Validation through direct interview examination neurologist was performed for GPs in patients under their care working at departments 3 hospitals. Results GP confirmed 44 cases (85%); (6%) had transient...
We studied the correlations between pattern of weakness, stroke type, topography, and etiology in 255 patients whose first was manifested by isolated hemiparesis. They represented 14% consecutively admitted patients. The weakness distributions were as follows: face, upper limb, lower limb (FUL) (50%); face (FU) (29%); (U) (10%); (UL) (9%). Twenty-nine percent had dysarthria, which no localizing value. Less than one half a deep infarct, third potential embolic source from heart or large...
The main factors influencing admission delay of stroke patients were investigated in 309 consecutive cases admitted to the emergency room a University hospital. All these examined and interviewed by neurologist. Forty-two percent (117 patients) arrived within 6 h onset symptoms. Extrahospital accounted for largest fraction time lost (82%), followed intrahospital (16%) transportation (2%). A medical contact prior our hospital significantly delayed (mean 35 vs. 23 h, t = 1.82, p 0.03)....
We sought to describe the frequency and location of headache in intracerebral hematoma (ICH) analyze its clinical CT predictors by means multivariate analysis.Headache is more common hemorrhage than ischemic stroke, varies with location, but pathophysiologic mechanisms associated ICH are not fully known.We examined a cohort 289 patients during 14-month period university hospital. Clinical, including presence headache, features were collected two neurologists.One hundred sixty-five (57%) had...
Background Diagnosing paroxysmal atrial fibrillation in patients with stroke can be difficult. We aimed to determine if N-terminal pro-brain natriuretic peptide help identify cryptogenic stroke. Methods and results Among 264 ischemic patients, serum levels of were measured within 72 h onset. In 24-h Holter monitoring was used look for the first week also three-and six-months after admission. First, a defined etiology construct receiver operating characteristic curve diagnosis fibrillation....
Recanalization status after intravenous thrombolysis (IVT) in patients with ischemic stroke is a reference point to proceed rescue reperfusion intervention, although early neurological improvement (NI) may preclude endovascular procedures. We aimed evaluate the importance of restoration blood flow at arterial occlusion site subgroups stratified by NI IVT.The following were recruited from Safe Implementation Treatment Stroke-International Stroke Thrombolysis Register: (1) baseline vessel...
Pregnancy is associated with increased risk of venous thrombotic events, including cerebral thrombosis. We aimed to study the complications and outcome subsequent pregnancies in women previous thrombosis.Follow-up acute thrombosis at childbearing age included a previously described cohort (International Study Cerebral Vein Dural Sinus Thrombosis). Patients were interviewed by local neurologists assess rate pregnancy outcomes, antithrombotic prophylaxis during pregnancies.A total 119...
We aimed to describe and classify headaches associated with acute stroke, by interviewing patients consecutively admitted a stroke unit using validated headache questionnaire the International Classification of Headache Disorders Society (IHS). One hundred twenty-four (61% ischaemic 39% haemorrhagic stroke) reported headache. Headaches started mostly on day were more often continuous, pressure-type, bilateral located in anterior region, increased movement cough lasted for mean 3.8 days....