A5037315619- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Neurological disorders and treatments
- Pharmacological Effects and Toxicity Studies
- Sleep and Wakefulness Research
- Neuroscience and Neuropharmacology Research
- Sleep and related disorders
- Acute Ischemic Stroke Management
- Neurological and metabolic disorders
- Neonatal and fetal brain pathology
- Parkinson's Disease Mechanisms and Treatments
- Restless Legs Syndrome Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Functional Brain Connectivity Studies
- Cardiac electrophysiology and arrhythmias
- Glycogen Storage Diseases and Myoclonus
- Traffic and Road Safety
- Sleep and Work-Related Fatigue
- Genetic Neurodegenerative Diseases
- Autoimmune Neurological Disorders and Treatments
- Neural and Behavioral Psychology Studies
- Blood Pressure and Hypertension Studies
- Cardiac Arrhythmias and Treatments
- Cerebrospinal fluid and hydrocephalus
- Respiratory and Cough-Related Research
Hospital de Santa Maria
2016-2025
University of Lisbon
2016-2025
Instituto Superior Politécnico do Oeste
2024-2025
Administração Regional de Saúde de Lisboa e Vale do Tejo
2025
Henry Ford Hospital
2025
The Royal Free Hospital
2021-2023
University College London
2021-2023
Centro Hospitalar Lisboa Norte
2011-2023
Tampere University Hospital
2023
Kempenhaeghe
2023
Importance Acute symptomatic seizures occurring within 7 days after ischemic stroke may be associated with an increased mortality and risk of epilepsy. It is unknown whether the type acute seizure influences this risk. Objective To compare epilepsy following different types seizures. Design, Setting, Participants This cohort study analyzed data acquired from 2002 to 2019 9 tertiary referral centers. The derivation included adults cohorts 2 case-control studies neuroimaging-confirmed without...
Objective The purpose of this study was to identify risk factors for acute symptomatic seizures and post‐stroke epilepsy after ischemic stroke evaluate the effects reperfusion treatment. Methods We assessed using logistic or Cox regression in a multicenter study, including adults from 8 European referral centers with neuroimaging‐confirmed stroke. compared between participants without treatment following propensity score matching reduce confounding due selection. Results In overall cohort...
The efficacy of deep brain stimulation the anterior nucleus thalamus (ANT DBS) in patients with drug-resistant epilepsy (DRE) was demonstrated double-blind Stimulation Anterior Nucleus Thalamus for Epilepsy randomized controlled trial. Medtronic Registry (MORE) aims to understand safety and longer-term effectiveness ANT DBS therapy routine clinical practice.
Electroencephalography (EEG) can identify biomarkers of epileptogenesis and ictogenesis. However, few studies have used EEG in the prediction poststroke seizures. Our primary aim was to evaluate whether early abnormalities predict epilepsy.
Functional magnetic resonance imaging (fMRI) studies enable the investigation of neural correlates underlying behavioral performance. We investigate working memory (WM) function patients with untreated obstructive sleep apnea (OSA) from view point task positive and default mode networks (TPN DMN, respectively) compare results to those healthy controls (HC).A parametric fMRI experiment 4 levels visuospatial N-back was used pattern cortical activation in 17 men moderate or severe OSA 7...
Background and purpose Intravenous alteplase (rt PA ) may be associated with seizures epileptic activity in the electroencephalogram (EEG). The aim of this work was to compare frequency EEG abnormalities between stroke patients treated not rt . Methods This a prospective study consecutive acute anterior circulation ischaemic patients, 1‐year follow‐up. Patients were previously independent, had an admission National Institute Health Stroke Scale score ≥4, lesion no previous seizures. They...
Summary Objective Seizures and electroencephalographic ( EEG) abnormalities have been associated with unfavorable stroke functional outcome. However, this association may depend on clinical imaging severity. We set out to analyze whether epileptic seizures early EEG are predictors of outcome after adjustment for age clinical/imaging infarct Methods A prospective study was made consecutive previously independent acute patients a National Institutes Health Stroke Scale (NIHSS) score ≥ 4...
Epilepsy is a neurological disease that affects ~50 million people worldwide, 30% of which have refractory epilepsy and recurring seizures, may contribute to higher anxiety levels poorer quality life. Seizure detection addressing some the challenges associated with this condition, by providing information health professionals regarding seizure frequency, type, and/or location in brain, thereby improving diagnostic accuracy medication adjustment, alerting caregivers or emergency services...
The most common ictal psychiatric symptom is fear, followed by depression, and least commonly psychosis. A 44-year-old man with poststroke focal epilepsy developed new-onset behavioural change, disorientation, hallucinations delusions, persisting for several months before medical evaluation. He was agitated, disorientated, impaired memory disorganised thinking, but had no minor epileptic motor signs. His EEG showed electroclinical status epilepticus. psychotic symptoms persisted despite...
BACKGROUND: Acute symptomatic seizures (ASyS) increase the risk of epilepsy and mortality after a stroke. The impact timing type ASyS remains unclear. METHODS: This multicenter cohort study included data from 9 centers between 2002 2018, with final analysis in February 2024. 4552 adults (2005 female; median age, 73 years) ischemic stroke no seizure history. Seizures were classified using International League Against Epilepsy definitions. We examined occurring within seven days main outcomes...
Increasing evidence suggests a role for circadian dysregulation in prompting disease-related phenotypes mammals. Cancer and neurodegenerative disorders are two aging related diseases reported to be associated with disruption. In this study, we investigated possible effect of disruption Parkinson's disease (PD) colorectal cancer (CRC). We used high-throughput data sets retrieved from whole blood idiopathic PD (IPD) patients time course derived an vitro model CRC including the wildtype three...
Sleep-related eating disorder (SRED) is characterised by episodes during the first period of night sleep with partial loss consciousness, and amnesia. It can rarely be induced some drugs, including zolpidem. We present a video report patient 1-year history SRED caused zolpidem causing important repercussions in structure life quality. The ceased promptly discontinuation Upon follow-up, improved daily consequences disappeared. As few reported cases zolpidem-induced SRED, our was suffering...
More than half of adults with epilepsy undergoing resective surgery achieve long-term seizure freedom and might consider withdrawing antiseizure medications. We aimed to identify predictors recurrence after starting postoperative medication withdrawal develop validate predictive models. performed an international multicentre observational cohort study in nine tertiary referral centres. included 850 who started following were free seizures other focal non-motor aware before withdrawal....