- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Moyamoya disease diagnosis and treatment
- Medical and Biological Ozone Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Meningioma and schwannoma management
- Venous Thromboembolism Diagnosis and Management
- Advanced MRI Techniques and Applications
- Neurosurgical Procedures and Complications
- Climate Change and Health Impacts
- Corporate Governance and Law
- Aortic aneurysm repair treatments
- Poisoning and overdose treatments
- Aortic Disease and Treatment Approaches
- Myofascial pain diagnosis and treatment
- Cardiovascular and Diving-Related Complications
- Oral and Maxillofacial Pathology
- Spinal Fractures and Fixation Techniques
- Working Capital and Financial Performance
- COVID-19 and healthcare impacts
Institute of Neurological Sciences
2012-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2013-2024
Istituto delle Scienze Neurologiche di Bologna
2013-2024
Ospedale Maggiore
2021-2023
Azienda di Rilievo Nazionale ed Alta Specializzazione
2022
Ospedale Bellaria
2008-2021
University of Bologna
2008-2013
The Silk stent (Balt, Montmorency, France) is a retractable device designed to achieve curative reconstruction of the parent artery associated with an intracranial aneurysm. We present our initial experience flow-diverting in management and follow-up 25 patients presenting aneurysms. Twenty-five (age range, 34–81 years; 24 female) were treated device. Aneurysms ranged size from small (5), large (10) giant included wide-necked aneurysms, multiple, nonsaccular, recurrent Nine aneurysms for...
All percutaneous minimally invasive disc treatments are typically indicated to contained herniations. Our study's aim is evaluate prospectively the efficacy of ozone nucleolysis in treatment either or uncontained lumbar
Intradiscal oxygen-ozone (O 2 -O 3 ) chemonucleolysis is a well-known effective treatment for pain caused by protruding disc disease and nerve root compression due to bulging or herniated disc. The most widely used therapeutic combination intradiscal injection of an O mixture (chemonucleolysis), followed periradicular , steroid local anaesthetic enhance the anti-inflammatory analgesic effect. designed resolve administered patients without motor weakness, whereas with acute paralysis undergo...
Background Stent-assisted coiling (SAC) is a well-established method for treatment of wide-necked intracranial aneurysms. In this multicenter, retrospective case series we evaluated SAC with new low-profile, laser-cut stent an antithrombogenic hydrophilic polymer coating (pEGASUS-HPC) the Methods Patients treated pEGASUS-HPC one or more aneurysms were retrospectively included. Clinical, imaging, and procedural parameters as well clinical imaging follow-up data recorded. Results We 53 in 52...
A multitude of therapies is available to treat disc herniation, ranging from conservative methods (medication and physical therapy) minimally invasive (percutaneous) treatments surgery. O 2 -O 3 chemonucleolysis (O one the with best cost/benefit ratio lowest complication rate. Another substance recently made exploiting chemical properties pure ethanol DiscoGel®, a radiopaque gelified more viscous than absolute alcohol 8,9 . The present study aimed assess therapeutic outcome DiscoGel® in...
Flow-diverting stents (Silk and PED) have radically changed the approach to intracranial aneurysm treatment from use of endosaccular materials an extraaneurysmal endoluminal device. However, much debate surrounds most appropriate indications for FD problems raised by several possible complications. We analysed our technical difficulties early (less than ten days after treatment) late complications encountered in 30 aneurysms treated comprising 13 giant lesions, 12 large, five with maximum...
Abstract Introduction A reduction of the hospitalization and reperfusion treatments was reported during COVID-19 pandemic. However, high variability in results emerged, potentially due to logistic paradigms adopted. Here, we analyze stroke code admissions, hospitalizations, belt performance for ischemic patients metropolitan Bologna region, comparing temporal trends between 2019 2020 define impact on network. Methods This retrospective observational study included all people admitted at...
Background The management of patients with poor-grade aneurysmal subarachnoid hemorrhage (aSAH) is burdened by an unfavorable prognosis even aggressive treatment. aim the present study to investigate risk factors affecting 30-day mortality in aSAH patients. Methods We performed a retrospective analysis prospectively collected database (World Federation Neurosurgical Societies, WFNS, grades IV and V) treated at our institution from December 2010 2020. For all variables, percentages frequency...
Endovascular treatment has assumed a major role in the management of intracranial aneurysms. Although current techniques have proven extremely effective embolization large number aneurysms, wide-necked basilar tip aneurysms represent subset that continues to pose technical challenges treatment. This study reports our experience with WEB II, new device employed four patients this type aneurysm.
Blood blister-like aneurysms (BBLA) are rare lesions sometimes difficult to recognize and in most cases associated with diffuse subarachnoid haemorrhage severe clinical conditions. BBLA life-threatening because they tend enlarge rapidly rebleed, no consensus has so far been reached on the best management strategy. We describe a patient right ICA treated successful by two-stage embolization procedure first coils an open cell stent (Neuroform 3) later further coil placement insertion of...
The spontaneous regression of disk herniation secondary to dehydration is a much-debated topic in medicine. Some physicians wonder whether surgical removal the extruded nucleus pulposus really necessary when disappearance herniated lumbar well-known phenomenon. Unfortunately, without regression, chronic pain leads progressive disability for which surgery seems be only solution. In recent years, several studies have demonstrated utility oxygen–ozone therapy treatment herniation, resulting...
The treatment of giant cerebral aneurysms has always been a challenge for neurosurgeons and neuroradiologists. Flow-diverting stents (Silk; Pipeline Embolization Device) are new endovascular devices introduced the intracranial without release intrasaccular coils. They tubular bimetallic endoluminal with low porosity. We have employed these in Neuroradiology Unit Bellaria Hospital (Bologna, Italy) since end 2008, treating nine patients carotid using Silk as soon device obtained CE mark. All...
Abstract Background Occlusion of the internal carotid artery (ICA), whether isolated or in setting a tandem lesion (TL) have poor response to treatment with intravenous thrombolysis. Previous studies have demonstrated superiority mechanical thrombectomy acute ischemic stroke (AIS) following large vessel occlusion, compared standard fibrinolysis. The aim our study was describe endovascular (EVT) AIS due ICA occlusion TL. Methods We assessed association between 90-day outcome and clinical,...
BACKGROUND: The flow-diverter devices (FDDs) safety and effectiveness have been demonstrated by large series meta-analyses. Due to the high occlusion rates acceptable morbidity of FDDs, indications for their use are continuously expanding. We presented our Italian multicentric experience using second generation DERIVO® Embolization Device (DED®; Acandis, Pforzheim, Germany) cure cerebral aneurysms, evaluating both middle long-term efficacy this device.METHODS: Between July 2016 September...
The treatment of giant, large, multiple or wide-necked carotid siphon aneurysms has always represented a challenge for neurosurgeons and neuroradiologists. Very recently the use stents with tiny holes been proposed by two companies: Balt Silk Stent in Europe Pipeline America. We have used stent on few patients describe our first case who now an eleven month follow-up. presented three converging sharing very large common neck. (Balt Extrusion, Montmorency, France) was deployed through 4F...
Deployment of stents across the neck intracranial aneurysms to isolate lesion from circulation is a recently introduced endovascular treatment. These devices are known as flow-diverting because stent mesh design drastically slows blood flow within aneurysm sac, thereby stimulating thrombus formation. Treated require close follow-up monitoring using an effective minimally invasive method. We devised dedicated protocol high field strength magnetic resonance system (MR) with gadolinium...
We report a patient suffering from spontaneous intracranial hypotension (SIH) who, following non-selective lumbar blood patch, returned to his healthcare provider with severe symptoms of neurological deficits. It was subsequently discovered that the aforementioned deficits were due bilateral subdural hematoma, and an emergency surgical drainage hematoma has been performed. However, reformed potential cerebrospinal fluid leakage consequently investigated through myelography. Following...
Balt (Montmorency, France) recently manufactured the Leo+Baby dedicated intracranial stent for arteries with a calibre between 1.5 and 3.10 mm. We describe patient partially thrombosed giant sacciform aneurysm of anterior communicating artery treated without success by surgery coil embolization subsequently occluded placement (Balt, Montmorency, France). A 56-year-old man presented in region. Following successive surgical intervention procedures was referred to us revascularized measuring...
Embolization is very effective in preventing bleeding of unruptured aneurysms with lower rates mortality and morbidity than surgical treatment. Neurosurgery remains, however, a good alternative. This retrospective analysis examined data stored the digital database Bellaria Hospital Radiology Department, evaluating patients, treatments devices used as well outcomes complications. Therapy should be tailored to each individual case offer patient best Out 265 intracranial detected, 182 were...
Cerebral aneurysms must be monitored for varying periods after surgical and/or endovascular treatment and the duration of follow-up will depend on type therapy immediate post-operative outcome. Surgical clipping intracranial is a valid but metal clips generate artefacts so that monitoring still relies catheter angiography. This study reports our preliminary experience with volumetric angiography using Philips Allura Xper FD biplane system in aneurysm residues or major vascular changes...
Low back pain and sciatica are highly debilitating conditions affecting all socioeconomic groups at an increasingly early age. They caused by different often concomitant spinal disorders: disc or facet joint disease, spondylolisthesis (with without listhesis), vertebral body interapophyseal arthrosis, stenosis, radicular synovial cysts and, more rarely, infections primary metastatic cancer.Treatment of low and/or requires accurate diagnosis based on thorough history-taking physical...