- Vestibular and auditory disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Ophthalmology and Eye Disorders
- Cerebral Venous Sinus Thrombosis
- Obstructive Sleep Apnea Research
- Genomics and Rare Diseases
- Ophthalmology and Visual Health Research
- Hearing Loss and Rehabilitation
- Migraine and Headache Studies
- Ear Surgery and Otitis Media
- Genetics and Neurodevelopmental Disorders
- Metabolism and Genetic Disorders
- Multiple Sclerosis Research Studies
- Neuroscience of respiration and sleep
- Axon Guidance and Neuronal Signaling
- Clinical Reasoning and Diagnostic Skills
- Cerebrospinal fluid and hydrocephalus
- Neurological and metabolic disorders
- COVID-19 and healthcare impacts
- Telemedicine and Telehealth Implementation
- Retinal and Optic Conditions
- Diet and metabolism studies
- Ocular Surface and Contact Lens
- Restraint-Related Deaths
- Connexins and lens biology
University of Ottawa
2018-2025
Ottawa Hospital
2018-2025
Ottawa Hospital Research Institute
2018-2025
Deleted Institution
2023
Children's Hospital of Eastern Ontario
2018
Background Dizziness is a common presenting symptom in the emergency department (ED). The HINTS exam, battery of bedside clinical tests, has been shown to have greater sensitivity than neuroimaging ruling out stroke patients with acute vertigo. present study sought assess practice patterns assessment ED peripherally-originating vertigo respect utilization and neuroimaging. Methods A retrospective cohort was performed using data pertaining 500 randomly selected visits at tertiary care centre...
Vertigo remains a diagnostic challenge for primary care, emergency, and specialist physicians. Multidisciplinary clinics are increasingly being employed to diagnose manage patients with dizziness. We describe, the first time in Canada, clinical characteristics of presenting chronic acute dizziness both multidisciplinary clinic (MDC) rapid access (RAD) at The Ottawa Hospital (TOH).We performed retrospective review all MDC RAD TOH from July 2015 August 2017.Overall, 211 (median age: 61 years...
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Abstract Introduction In 2022, nearly 0.5 million Canadians visited an emergency department (ED) for dizziness, accounting over 3.5% of all ED visits. Of these patients, only 2%–5% received a serious diagnosis. The cost and inpatient care dizziness in Canada exceeds $200 per year, which neuroimaging accounts large proportion. Over one‐third patients undergo CT scan the head, 96% are negative. Despite extensive investigation, discharged with benign diagnosis have 50‐fold increased risk being...
ATP8A2 mutations have recently been described in several patients with severe, early-onset hypotonia and cognitive impairment. The aim of our study was to characterize the clinical phenotype mutations.An observational conducted at multiple diagnostic centres. Clinical data is presented from 9 unreported 2 previously reported mutations. We compare their features 3 additional that medical literature.Eleven biallelic were identified, a mean age 9.4 years (range 2.5-28 years). All (100%)...
Erythrokeratodermia (EK) is a rare skin disorder, likely genetic and usually present from infancy.1 There patchy symmetrical involvement over the body surface, manifested in progressive figurate plaques of hyperkeratosis more transient areas erythema. significant overlap clinical features "variabilis" "progressiva" forms EK. Restricted cutaneous syndromes EK have been described associated with mutations connexin ( GJB3, GJB4 , GJA1 ) loricrin LOR genes. The majority patients EK, however, no...
To assess the usefulness of head and neck computed tomography angiogram for investigation isolated dizziness in emergency department detecting significant acute findings leading to a change management comparison non-contrast scan head.Patients presenting with investigated over span 36 months were included. Findings on classified as related presentation versus unrelated/no abnormality. Similarly, scans positive or negative posterior circulation findings.One hundred fifty-three patients imaged...
Persistent Postural Perceptual Dizziness (PPPD) is a newly defined condition which was added to the International Classification of Vestibular Disorders in 2017. Little known about its impact on patients.The goal this study analyze symptomology, epidemiology and PPPD patients.A retrospective chart review done identify patients who attended Multidisciplinary Clinic (MDC) were diagnosed with PPPD. Responses demographic questions, health-related quality life surveys several well-validated...
Study objectiveIdentify high-risk clinical characteristics for a serious cause of vertigo in patients presenting to the emergency department (ED).MethodsMulticentre prospective cohort study over 3 years at three university-affiliated tertiary care EDs. Participants were with vertigo, dizziness or imbalance. Main outcome measurement was an adjudicated diagnosis defined as stroke, transient ischemic attack, vertebral artery dissection brain tumour.ResultsA total 2,078 2,618 potentially...
Background In the Canadian health care system, determining overall costs associated with a particular diagnostic subgroup of patients, in this case dizzy is first step process where could be saved without compromising patient care. This study that evaluates these at tertiary hospital and will allow for extrapolation cost data other similar academic science centers, regional initiatives, provincial healthcare planning structures. Methods We conducted retrospective cohort patients any age...
We aimed to evaluate the perceived effectiveness of interventions implemented by Canadian neurology residency programs for 2020-2021 iteration Resident Matching Service (CaRMS).A cross-sectional survey was distributed and final-year medical students who applied at least one program during match cycle. The surveys evaluated pre-interview interview period accessed students.Thirty-five 13 out 15 institutions in Canada with responded survey. Multiple adaptations were implemented, including...
Obstructive sleep apnea (OSA) has been linked to vestibular dysfunction, but no prior studies have investigated the relationship between Persistent Postural-Perceptual Dizziness (PPPD), a common cause of chronic dizziness, and OSA.We determined frequency OSA in an uncontrolled group PPPD patients from tertiary dizziness clinic based on polysomnogram (PSG). We then assessed sensitivity specificity questionnaires this population.Twenty-five with underwent PSG (mean age 47, 60% female, mean BMI...
Abstract Objectives Identify high-risk clinical characteristics for a serious cause of vertigo in patients presenting to the emergency department. Design Multicentre prospective cohort study over 3 years. Setting Three university-affiliated tertiary care departments. Participants Patients with vertigo, dizziness or imbalance. A total 2078 2618 potentially eligible (79.4%) were enrolled (mean age 77.1 years; 59% women). Main outcome measurements An adjudicated diagnosis defined as stroke,...
The bedside head impulse test (bHIT) is a clinical method of assessing the vestibulo-ocular reflex (VOR). It critical component assessment dizzy patients, and can help differentiate acute stroke from vestibular neuritis. However, there evidence showing bHIT often not performed in appropriate settings or poorly. To date, have been no studies evaluating competence graduating physicians.23 final year Otolaryngology -Head &Neck Surgery (OTL-HNS) residents Canada were evaluated on use using...
Abstract Background Headache disorders are the most common neurological worldwide. Despite their widespread prevalence and importance, topic of headache is inconsistently taught at both undergraduate postgraduate levels. The goal this study to establish a better picture current state Medicine (HM) training in Neurology programs Canada describe impact pandemic on domain. Methods Online surveys were sent senior residents adult Canada. We also conducted telephone interviews with Program...
Background: ATP8A2 mutations have only recently been associated with human disease. We present the clinical features from largest cohort of patients this disorder reported to date. Methods: An observational study 9 unreported and 2 previously biallelic was carried out at multiple centres. Results: The mean age 9.4 years old (range: 2.5-28 yrs). All demonstrated developmental delay, severe hypotonia movement disorders: chorea/choreoathetosis (100%), dystonia (27%) or facial dyskinesia (18%)....
Bourque, Pierre R. MD; Grimes, David A. Lelli, Daniel MDEditor(s): Avery, Robert DO; Golnik, Karl C. Froment, Caroline MD, PhD; Wang, An-Gour MD Author Information
We present a clinical reasoning case of 42-year-old male with history type 1 diabetes who presented to hospital decreased level consciousness. review the approach coma including initial differential diagnosis and investigations. After refining diagnostic options based on investigations, we decision-making process focus narrowing diagnosis, further treatment.
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