A5088136426- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Cardiovascular Disease and Adiposity
- Health Systems, Economic Evaluations, Quality of Life
- Coronary Interventions and Diagnostics
- Cardiac tumors and thrombi
- Cardiac electrophysiology and arrhythmias
- Pulmonary Hypertension Research and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Chemotherapy-induced cardiotoxicity and mitigation
- Congenital Heart Disease Studies
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular and exercise physiology
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Heart Rate Variability and Autonomic Control
- Cardiac Health and Mental Health
Hospital de Santa Marta
2016-2025
Universidade Nova de Lisboa
2017-2025
Bandung Institute of Technology
2024-2025
University of Lisbon
2024
Sociedade Portuguesa de Cardiologia
2018-2023
Centro Hospitalar de Lisboa Central
2012-2023
Dutch Colorectal Cancer Group
2023
Collaborative Group (United States)
2023
British Heart Foundation
2022
University of Leeds
2022
Abstract Aim Fatality of infective endocarditis (IE) is high worldwide, and its diagnosis remains a challenge. The objective the present study was to compare clinical characteristics outcomes patients with culture-positive (CPIE) vs. culture-negative IE (CNIE). Methods results This an ancillary analysis ESC-EORP EURO-ENDO registry. Overall, 3113 who were diagnosed during period included in study. Of these, 2590 (83.2%) had CPIE, whereas 523 (16.8%) CNIE. As many as 1488 (48.1%) underwent...
Atrial fibrillation has been a difficult problem to solve in many surgical patients, especially those with mitral valve pathology. This study evaluates the results of endocardial and epicardial radiofrequency ablation new intra-operative device treatment atrial fibrillation.We operated on 65 patients fibrillation, 58 which had concomitant surgery. was chronic (over 1 year) 46 (group A) paroxysmal or recent onset 12 B). Group C lone (two), coronary artery disease (four) sarcoma (one)....
O Registo Nacional de Síndromes Coronárias Agudas (SCA) completa agora 15 anos atividade contínua prospetiva. Descrevemos no presente trabalho os dados gerais obtidos a partir dessa poderosa ferramenta. Incluíram‐se até ao momento 45 141 registos, maioria do sexo masculino (71%), com idade média 66 anos, características basais que se têm mantido estáveis. Da população total, 44% são enfartes elevação segmento ST (EMCST). Ao longo dos verificou‐se uma melhoria muito significativa cumprimento...
The carotid bodies (CBs) are peripheral chemoreceptor organs classically described as being O2 sensors, which increasingly emerging core players in metabolic control. Herein we evaluated CB activity prediabetes patients and determined its correlation with dysmetabolism clinical features.Prediabetes were recruited at the Cardiology Service, Hospital Santa Marta, Centro Hospitalar Lisboa Central, EPE (CHLC-EPE). study was approved by CHLC-EPE NOVA Medical School Ethics Committee. Thirty-three...
Left ventricular global longitudinal strain (GLS) has incremental prognostic value over ejection fraction (EF) in patients with ST-segment-elevation myocardial infarction (STEMI), but it is also load dependent. It been recently demonstrated that Myocardial work (MW), integrating blood pressure GLS, predicts long-term all-cause mortality. We aimed to further explore the of MW for cardiovascular endpoints STEMI.
Right ventricular myocardial work (RVMW) assessed by transthoracic echocardiography allows to study the right (RV) function using RV pressure-strain loops. The assessment of these novel indexes RVMW has not yet been exten sively studied, namely in pre-capillary pulmonary hypertension (PH) population. evaluate relationship between and invasive indices heart catheterization (RHC) a cohort patients with group I IV PH compare control without PH. A prospective registry was used compared In both...
Abstract Background Right ventricular (RV) – pulmonary arterial (PA) coupling represents the relationship between RV function and afterload in vascular system. It is a non-invasive surrogate on how adapted to an increased circulation. In cases of exhaustion compensatory remodeling, ratio decreases there RV-PA uncoupling. Several studies reported usefulness this parameter patients with heart failure, including preserved ejection fraction. There no evidence regarding association hypertrophic...
Baroreflex activation therapy (BAT) is a novel treatment for heart failure with reduced ejection fraction (HFrEF) in patients who remain symptomatic despite optimal medical (OMT) and are unsuitable cardiac resynchronization (CRT). BAT modulates the autonomic nervous system by electrically stimulating carotid baroreceptors, thus potentially improving function symptoms. Two male HFrEF nonischemic cardiomyopathy, (NYHA functional class III) OMT, underwent successful implantation. Patient 1,...
Levosimendan infusion in the outpatient setting improves clinical status of heart failure (HF) patients, although its hemodynamic effects are not entirely known. Remote monitoring using CardioMEMSTM system enables daily assessment pulmonary artery pressure (PAP) and estimation cardiac output (CO). We aimed to assess levosimendan CardioMEMSTM. All patients admitted for 6-hour (performed every 14 days) remote were included a prospective single-center registry. Clinical laboratory data...
We estimated the average direct cost per Acute Coronary Syndromes (ACS) in-patient episodes by diagnosis, namely ST-elevation myocardial infarction (STEMI), non-ST elevation (NSTEMI), unstable angina (UA), and undetermined AMI (Acute Myocardial Infarction). also analyzed changes in costs over time between 2002 2022, total economic burden of ACS hospitalizations for Portuguese National Health Service (NHS). used Registry (61,440 hospitalizations), a cohort people with ACS, recruited followed...
BackgroundBicuspid aortic valve is the most common CHD. Its association with early valvular dysfunction, endocarditis, thoracic aorta dilatation, and dissection well established.ObjectiveThe aim of this study was to assess incidence predictors cardiac events in adults bicuspid valve.MethodsWe carried out a retrospective analysis outcomes ambulatory followed-up tertiary hospital centre. Outcomes were defined as follows: interventional – intervention on or aorta; medical death, dissection,...
Cardiovascular disease, and particularly myocardial infarction (MI), carries a significant economic burden, through productivity losses (indirect costs) associated with temporary absence from work, that has not yet been adequately studied in Portugal. Our objective was to quantify the indirect costs of MI first year after admission. Consecutive patients admitted single center aged <66 years who survived discharge during one-year period were included. Employment status on admission assessed...
Purpose: The aim was to characterise acute coronary syndrome patients with complete atrioventricular block and assess the effect on outcome. Methods: Patients admitted were divided according presence of block: group 1, block; 2, without block. Clinical, electrocardiographic echocardiographic characteristics prognosis during one year follow-up compared between groups. Results: Among 4799 study period, 91 (1.9%) presented At presentation, 1 lower systolic blood pressure, higher Killip class...
Insulin resistance is the pathophysiological key to explain metabolic syndrome. Although clearly useful, Homeostasis Model Assessment index (an insulin measurement) has not been systematically applied in clinical practice. One of main reasons discrepancy cut-off values reported different populations. We sought evaluate a Portuguese population ideal for and assess its relationship with syndrome.We selected cohort individuals admitted electively Cardiology ward BMI < 25 Kg/m2 no abnormalities...
Abnormal glucose metabolism is a predictor of worse outcome after acute coronary syndrome (ACS). However, this parameter not included in risk prediction scores, including GRACE score. We sought to evaluate whether the inclusion blood at admission model with score improves stratification. Study consecutive patients single centre registry ACS. Our primary endpoint was occurrence all-cause mortality one-year follow-up. The ability two logistic regression models (GRACE alone and combination...
The benefits of patent foramen ovale (PFO) closure for cryptogenic stroke secondary prevention are still debated. Risk Paradoxical Embolism (RoPE) study developed a score to improve patient selection this procedure. We proposed assess the validity prognostic impact PFO closure.
Serum uric acid (UA) has been shown to be an independent predictor of outcome in the general population and patients with heart failure. There are, however, limited data regarding prognostic value UA context acute coronary syndromes (ACS) particularly medium-term follow up available results are contradictory.Study consecutive admitted ACS (with without ST-segment elevation) at a single-centre care unit. Primary endpoint was all-cause mortality 1-year up. We evaluated if serum is it any added...
There are barriers to proper implementation of risk stratification scores in patients with acute coronary syndromes (ACS), including their complexity. Our objective was develop a simple score for all-cause in-hospital mortality population ACS.The developed from nationwide ACS registry. The development and internal validation cohorts were obtained the first 31829 patients, randomly separated (60% 40%, respectively). external cohort consisted last 8586 included This is significantly different...