A5075202892- Cardiomyopathy and Myosin Studies
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Structural Anomalies and Repair
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Infective Endocarditis Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Cardiovascular and Diving-Related Complications
- Cardiac tumors and thrombi
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Mesenchymal stem cell research
- Coronary Artery Anomalies
- Cerebrovascular and Carotid Artery Diseases
- Aortic aneurysm repair treatments
- Mechanical Circulatory Support Devices
- Cardiovascular Disease and Adiposity
Hospital de Santa Marta
2016-2025
Centro Hospitalar de Lisboa Central
2013-2024
Hospital de Santo António
2019
Centro Hospitalar do Porto
2019
Universidade Nova de Lisboa
2015
Instituto Politécnico de Lisboa
2005
Abstract Background Novel echocardiographic speckle-tracking techniques such as global longitudinal strain (GLS) and myocardial work (MW) have been used in many cardiac conditions for functional assessment. In severe aortic stenosis (SAS) this evaluation is more challenging since left ventricular (LV) systolic pressure (SP) does not equal non-invasive (NISP) owing to the fixed obstruction of a stenotic valve. Few studies evaluated immediate impact transcatheter valve replacement (TAVR)...
Abstract Background Microvascular dysfunction (MVD) constitutes one of the most important pathophysiological features in hypertrophic cardiomyopathy (HCM). Chronic and recurrent myocardial ischemia potentially contributes to arrhythmic risk, namely atrial fibrillation (AF). Purpose To analyze impact MVD occurrence AF HCM patients (P), assessed by coronary flow velocity reserve (CFVR) on echocardiography (echo) cardiovascular magnetic resonance (CMR). Methods Prospective study, which enrolled...
Background Two-dimensional speckle tracking echocardiography has been shown to correlate with microvascular dysfunction, a hallmark of hypertrophic cardiomyopathy (HCM). We hypothesized that there is an association between myocardial work and left ventricular ischemia, incremental value global longitudinal strain, in patients HCM. Methods Results performed prospective assessment HCM, undergoing 2-dimensional stress perfusion cardiac magnetic resonance. were stratified according obstructive...
The benefits of patent foramen ovale (PFO) closure for cryptogenic stroke secondary prevention are still debated. Risk Paradoxical Embolism (RoPE) study developed a score to improve patient selection this procedure. We proposed assess the validity prognostic impact PFO closure.
Background Mesenchymal stem/stromal cells have unique properties favorable to their use in clinical practice and been studied for cardiac repair. However, these are larger than coronary microvessels there is controversy about the risk of embolization microinfarctions, which could jeopardize safety efficacy intracoronary route delivery. The index microcirculatory resistance (IMR) an invasive method quantitatively assessing microcirculation status. Objectives To examine heart after injection...
In obstructive hypertrophic cardiomyopathy (HCM), alcohol septal ablation (ASA) can lead to gradient reduction and symptom improvement. We aimed assess the efficacy safety of ASA in a long-term outcome study. analyzed patients who underwent over seven-year period tertiary center. The primary echocardiographic endpoint was >50% left ventricular outflow tract (LVOT) within year procedure. clinical endpoints were improvement functional capacity combined cardiac death rehospitalization for...
Aims: The aim of the study is to investigate association between degree ischemia due coronary microvascular dysfunction (CMD) and left ventricular (LV) tissue characteristics, systolic performance, clinical manifestations in hypertrophic cardiomyopathy (HCM). Methods Results: This prospective enrolled 75 patients with HCM without obstructive epicardial artery disease. Each patient underwent cardiovascular magnetic resonance (CMR) including parametric mapping, perfusion imaging during...
Microvascular dysfunction is an often overlooked feature of hypertrophic cardiomyopathy (HCM). Our aim was to assess the association between microvascular dysfunction, wall thickness, tissue characteristics and myocardial deformation in HCM patients, by analyzing individual segments. Prospective assessment including cardiac magnetic resonance T1 T2 mapping, extracellular volume, late gadolinium enhancement (LGE) stress perfusion. Results were stratified according 16 American Heart...
A case series on different vascular malformations (VM) treated with percutaneous occlusion in children and adults is presented.Percutaneous usually the preferred treatment method for VM. Previous have mostly focused single types of devices and/or VM.Retrospective analysis all patients who underwent VM a center, from 1995 to 2014, excluding patent ductus arteriosus. Clinical angiographic data, procedural details, implanted devices, complications were assessed. Procedural success was defined...
PurposeNoninvasive ischemia testing (NIST) is recommended for most patients suspected to have stable coronary artery disease (CAD) before invasive angiography (ICA). We sought assess the diagnostic predictive ability of NIST over clinical risk profiling in a contemporary sample undergoing currently triage strategy. MethodsFrom 2006 2011, 2,600 consecutive without known CAD elective ICA single tertiary-care center were retrospectively identified and prevalence obstructive determined. To...
A ablação septal alcoólica (ASA) é a forma percutânea de tratamento invasivo da cardiomiopatia hipertrófica obstrutiva (CMHO). propósito descrição experiência no nosso centro, procurar-se-á rever as indicações, os aspetos técnicos e práticos resultados ASA, assim como sua posição atual em comparação com miectomia cirúrgica. Avaliar ASA numa série doentes consecutivos tratados nos primeiros quatro anos atividade. Estudo retrospetivo todos doentes, não selecionados, CMHO, por entre janeiro...
We report the case of a 52-year-old man who presented to our emergency department (ED) after three episodes syncope in seven hours before admission. During his stay ED he had recurrent ventricular tachycardia (VT) requiring external electrical cardioversion. A 12-lead electrocardiogram (ECG) showed short QT (SQT) interval (270 ms, QTc 327 ms), with frequent R-on-T extrasystoles triggering sustained polymorphic VT. After exclusion other precipitating causes, patient was diagnosed as having...
Paravalvular leak (PVL) is a common serious complication associated with prosthetic valve implantation. The aim of this study was to report our single-center experience in retrospective review and analyze possible predictors success. We performed 33 percutaneous PVL closures 26 patients (54% female, mean age 65±13 years). All mitral prostheses were studied previously 3D transesophageal echocardiography (TEE), aortic 2D/3D TEE. TEE fluoroscopy used for the assessment, planning, guidance...
Transesophageal echocardiography (TEE) has been the standard method for guiding left atrial appendage occlusion (LAAO) procedures. Recently, intracardiac (ICE) emerged as an alternative to TEE due several advantages, particularly avoidance of general anesthesia. This analysis aims assess safety, feasibility and efficacy ICE-guided LAAO procedures.We performed a retrospective procedures, including comparison embolic bleeding events with predicted scores TEE-guided procedures.A total 88...