A5002112140- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Moyamoya disease diagnosis and treatment
- Animal Nutrition and Physiology
- Connective tissue disorders research
- Intracerebral and Subarachnoid Hemorrhage Research
- Rabbits: Nutrition, Reproduction, Health
- Cardiovascular Health and Disease Prevention
- Cardiac and Coronary Surgery Techniques
- Peripheral Artery Disease Management
- Galectins and Cancer Biology
- Cardiovascular and Diving-Related Complications
- Ultrasound Imaging and Elastography
- Moringa oleifera research and applications
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Vascular Procedures and Complications
- Ruminant Nutrition and Digestive Physiology
Mayo Clinic in Arizona
2016-2025
Mayo Clinic
2016-2025
WinnMed
2008-2025
Neurological Surgery
2023-2025
Mayo Clinic in Florida
2014-2025
Bicêtre Hospital
2024-2025
Shanghai Jiao Tong University
2025
Vall d'Hebron Institut de Recerca
2025
Tehran University of Medical Sciences
2025
University of Miami
2025
Background and Purpose— We report a preclinical study of new endoluminal device for aneurysm occlusion to test the hypothesis that device, even without use intrasaccular coil placement, could occlude saccular aneurysms causing substantial parent artery compromise or adjacent, small branch arteries. Methods— The Pipeline Neuroendovascular Device (Pipeline NED; Chestnut Medical Technologies, Inc) is braided, tubular, bimetallic implant aimed at through flow disruption along neck. was implanted...
Super-resolution ultrasound microvessel imaging with contrast microbubbles has recently been proposed by multiple studies, demonstrating outstanding resolution high potential for clinical applications. This paper aims at addressing the noise issue in vivo human super-resolution ultrafast plane-wave imaging. The rich spatiotemporal information provided presents features that allow microbubble signals to be separated from background noise. In addition, high-frame-rate recording of data enables...
Purpose To compare gadolinium tissue concentrations of multiple linear and macrocyclic chelates in a rat model to better understand the scope extent deposition following intravenous doses gadolinium-based contrast agent (GBCA). Materials Methods In this Institutional Animal Care Use Committee-approved study, healthy rats received 20 injections 2.5 mmol per kilogram (gadolinium-exposed group) or saline (control over 26-day period. Unenhanced T1 signal intensities dentate nucleus were measured...
Mechanical thrombectomy (MT) has revolutionized the treatment of acute ischemic stroke (AIS) due to large vessel occlusion (LVO), but its efficacy and safety in medium (MeVO) remain less explored. This multicenter, retrospective study aims investigate incidence clinical outcomes perforations (confirmed by extravasation during an angiographic series) MT for AIS caused MeVO.
Abstract 1. The effect of dietary probiotic supplementation on the growth, nitrogen utilisation and serum cholesterol content broiler chickens was studied in 2 trials. 2. In experiment 1, birds receiving 0, 75, 100, 125 mg probiotic/kg diets had weight gains 1204.0, 1272.0, 1268.3 1210.5 g, respectively at end 8 weeks feeding. group fed 75 supplemented diet retained significantly (P<0.01) more than control birds. Serum lower probiotic‐supplemented (93.3 mg/100 ml) compared to (132.2 ml). 3....
We report a preclinical study of second-generation endoluminal device (Pipeline Embolization Device [PED-2] for aneurysmal occlusion and compare the PED-2 with its first-generation predecessor (PED-1).Our Institutional Animal Care Use Committee approved all studies. The is braided endoluminal, flow-diverting was implanted across necks 18 elastase-induced aneurysms in New Zealand white rabbits followed 1 month (n = 6), 3 months 6 6). A second abdominal aorta to cover origins lumbar arteries....
To characterize the progression of healing across aneurysm necks following treatment with a flow diverter in rabbit model.With institutional animal care and use committee approval, saccular aneurysms were created 20 rabbits treated diverters. On days 1, 3, 7 weeks 4 8 after implantation, device-implanted vessel harvested. En face staining gross specimen was performed for endothelial cells, progenitor smooth muscle inflammatory cells.The parent artery segments covered by diverters completely...
<h3>BACKGROUND AND PURPOSE:</h3> The WEB device is an intrasaccular ellipsoid braided-wire embolization designed to provide flow disruption along the aneurysm neck. purpose of this study was evaluate, in vivo model, acute and chronic performance regarding immediacy, degree, durability occlusion. <h3>MATERIALS METHODS:</h3> implanted 24 elastase-induced aneurysms New Zealand white rabbits followed for 1, 3, 6, 12 months (<i>n</i> = 6 at all time points). Degree intra-aneurysmal graded on a...
Robust wall apposition for flow-diverter stents may be important endothelialization. Using a large series of experimental aneurysms treated with the Pipeline Embolization Device, objectives this study were to 1) assess interobserver agreement evaluation on posttreatment DSA and evaluate its association aneurysm occlusion, 2) measure relationship between assessed histology occlusion rate after treatment.Saccular created in 41 rabbits Device. was performed just deployment device at follow-up....
Background Clot perviousness in large vessel occlusion has been shown to be associated with improved recanalization outcomes mechanical thrombectomy and intravenous thrombolysis. Objective To evaluate the association between clot based on thrombus attenuation increase (TAI) CT, histologic composition of clots acute ischemic stroke (AIS). Methods A retrospective review was completed patients AIS secondary occlusion, non-contrast CT (NCCT) angiography (CTA) images, analysis retrieved clot. TAI...
We retrospectively evaluated the composition of retrieved clots from ischemic stroke patients to study association between histological and etiology METHODS: Consecutive enrolled in Stroke Thromboembolism Registry Imaging Pathology (STRIP) were included this study. All underwent mechanical thrombectomy sent a central core lab for processing. Histological analysis was performed using martius scarlet blue (MSB) staining, quantification red blood cells (RBCs), white (WBCs), fibrin platelets...
Background The combination of intravenous thrombolysis (IVT) with mechanical thrombectomy (MT) may have clinical benefits for patients medium vessel occlusion. Purpose To examine whether MT combined IVT is associated different outcomes than alone in acute ischemic stroke (AIS) and Materials Methods This retrospective study included consecutive adult AIS occlusion treated or at 37 academic centers North America, Asia, Europe. Data were collected from September 2017 to July 2021. Propensity...
Abstract 1. The effect of probiotic supplementation on egg production, serum and yolk cholesterol shell thickness in 24 White Leghorn layers was studied from 28–38 weeks age. 2. In 3 treatments the diet supplemented with 0, 100 150 mg probiotic/kg food. 3. group, production improved by 5%, slightly, fewer thin‐shelled eggs than control (8.6% compared to 18.6%). 4. initial concentration 170.2 mg/dl birds remained similar throughout 10‐week experimental period, whereas group value 176.5...