Lian Liu

ORCID: 0000-0003-4238-4842
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About
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Research Areas
  • Cerebrovascular and Carotid Artery Diseases
  • Acute Ischemic Stroke Management
  • Neurological Disease Mechanisms and Treatments
  • Intracranial Aneurysms: Treatment and Complications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Ideological and Political Education
  • Facial Nerve Paralysis Treatment and Research
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Venous Thromboembolism Diagnosis and Management
  • Stroke Rehabilitation and Recovery
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Vascular Malformations Diagnosis and Treatment
  • Health and Wellbeing Research
  • Educational Reforms and Innovations
  • S100 Proteins and Annexins
  • COVID-19 and Mental Health
  • Bone and Joint Diseases
  • Advances in Cucurbitaceae Research
  • Ear Surgery and Otitis Media
  • Acupuncture Treatment Research Studies
  • Autophagy in Disease and Therapy
  • Medical Imaging and Analysis
  • Robotic Path Planning Algorithms
  • Autonomous Vehicle Technology and Safety
  • MicroRNA in disease regulation

Dalian Neusoft University of Information
2025

Guizhou University
2024

Beijing Tian Tan Hospital
2015-2024

Capital Medical University
2015-2024

Sichuan University
2014-2024

West China Hospital of Sichuan University
2014-2024

Wenzhou Medical University
2024

Shanghai Jiao Tong University
2002-2024

State Key Laboratory of Biotherapy
2024

Wuhan University
2020-2024

The role of endovascular therapy for acute stroke with a large infarction has not been extensively studied in differing populations. Download PDF the Research Summary. We conducted multicenter, prospective, open-label, randomized trial China involving patients large-vessel occlusion anterior circulation and an Alberta Stroke Program Early Computed Tomography Score 3 to 5 (range, 0 10, lower values indicating larger infarction) or infarct-core volume 70 100 ml. Patients were randomly assigned...

10.1056/nejmoa2213379 article EN New England Journal of Medicine 2023-02-10

Background and Purpose: A recent randomized controlled trial DIRECT-MT (Direct Intra-Arterial Thrombectomy to Revascularize AIS Patients With Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals) compared the safety efficacy of mechanical thrombectomy (MT) versus combined intravenous thrombolysis (IVT) MT for acute large vessel occlusion. The current study utilized a prospective, nationwide registry validate results real-world practice setting. Methods: Subjects were selected...

10.1161/strokeaha.120.031599 article EN Stroke 2021-03-04

ObjectiveTo investigate whether inflammatory indices, including the systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), product of platelet and neutrophil count (PPN), lymphocyte-to-monocyte (LMR), correlate with chronic obstructive pulmonary disease (COPD).MethodsThis was a cross-sectional study from National Health Nutrition Examination Survey (NHANES) database 2007-2018. The SII, NLR, PLR, PPN LMR were calculated based on blood...

10.1016/j.heliyon.2024.e31524 article EN cc-by Heliyon 2024-05-01

In patients undergoing mechanical thrombectomy (MT), adjunctive antithrombotic might improve angiographic reperfusion, reduce the risk of distal emboli and reocclusion but possibly expose to a higher intracranial hemorrhage risk. This study evaluated safety efficacy combined MT plus eptifibatide for acute ischemic stroke. was propensity-matched analysis data from 2 prospective trials in Chinese populations: ANGEL-ACT trial (Endovascular Treatment Key Technique Emergency Workflow Improvement...

10.1161/strokeaha.121.036754 article EN Stroke 2022-02-02

Nonalcoholic fatty liver disease (NAFLD) is a kind of lipid synthesis and degradation imbalance related with metabolic syndrome. Celecoxib shows the function ameliorating NAFLD, but underlying mechanisms remain unknown. Here, we discuss possible celecoxib alleviating NAFLD by restoring autophagic flux. Lipids were accumulated in L02 cells treated palmitate as well SD rats fed high-fat diet. Western blot showed that LC3 II/I was higher p62 lower on early stage steatosis while late both them...

10.1038/s41598-018-22339-0 article EN cc-by Scientific Reports 2018-03-01

Heart failure is a common adverse postoperative complication in elderly patients. It necessary to explore the risk factors of heart after operation patients with hip fracture during hospitalization.Patients fractures admitted our hospital from January 1, 2019 December 31 2020 were included, all received internal fixation surgery. The characteristics and without compared. Multivariate logistic regression analyses applied analyze fracture.A total 283 incidence was 12.37 %. There significant...

10.1186/s12891-021-04686-8 article EN cc-by BMC Musculoskeletal Disorders 2021-09-28

As China advances its carbon reduction efforts, the equitable and efficient allocation of initial quotas among provinces has become increasingly critical. This study proposes a novel two-stage Adjusting Measures to Local Conditions (AMLC) framework that integrates regional development disparities marginal abatement costs into quota process. Employing PSO-LSSVM model for emission estimation hierarchical clustering algorithm, this categorizes 30 Chinese six distinct types, facilitating...

10.1371/journal.pone.0321644 article EN cc-by PLoS ONE 2025-04-23

Background: Sporadic data showed hyperglycemia at presentation is associated with poor outcomes in patients acute ischemic stroke (AIS) under mechanical thrombectomy (MT) treatment. Objective: This study aims to evaluate the relationship of admission and treated solitaire stent thrombectomy. Methods: multicenter prospective registered AIS due anterior circulation large vessel occlusion (LVO) suitable for MT Solitaire retriever. We analyzed influence (≥7.8 mmol/L) serum glucose on functional...

10.3389/fneur.2019.00071 article EN cc-by Frontiers in Neurology 2019-02-19

An efficient HMFCA production strategy was developed using a new whole-cell biocatalyst from <italic>Pseudomonas aeruginosa</italic> PC-1.

10.1039/d0re00018c article EN Reaction Chemistry & Engineering 2020-01-01

Thrombelastography (TEG) is widely used for the measurement of platelet function. However, few studies have investigated TEG parameters in patients receiving extracranial or intracranial artery stenting ischemic cerebrovascular disease. This study sought to describe association before procedure with post-procedural events after stenting.Patients whom was performed stenosis (70-99%) were recruited into study. Blood samples obtained assess function stenting. The primary endpoint stroke...

10.1136/neurintsurg-2015-011687 article EN Journal of NeuroInterventional Surgery 2015-06-03

The role of stroke etiology subtype in patients with acute large vessel occlusion on the occurrence hemorrhagic transformation (HT) after endovascular treatment is poorly studied, and which factors mediate their relationship remains largely unknown. We utilized nationwide registry data to explore association (cardioembolism versus artery atherosclerosis) HT identify possible mediators.A total 1015 subjects were selected from ANGEL-ACT (Endovascular Treatment Key Technique Emergency Work Flow...

10.1161/strokeaha.121.037411 article EN Stroke 2022-03-31

Background: Sex steroid hormones, including testosterone and estradiol, play significant roles in various aspects of pulmonary health diseases.However, although there were a few studies trying to link sex hormones with COPD, their effect remained limited due small sample size insufficient causal results.This study aims investigate the association between chronic obstructive disease (COPD) based on National Health Nutrition Examination Survey (NHANES) database evaluate causality via...

10.2147/copd.s463849 article EN cc-by-nc International Journal of COPD 2024-07-01

Background Cerebral arteriovenous malformation (AVM) is a cerebrovascular disorder posing risk for intracranial hemorrhage. However, there are few reliable quantitative indices to predict hemorrhage accurately. This study aimed identify potential biomarkers by quantitatively analyzing the hemodynamic and morphological features within AVM nidus. Methods included three datasets comprising consecutive patients with untreated AVMs between January 2008 December 2023. Training test were used train...

10.1136/jnis-2024-022208 article EN Journal of NeuroInterventional Surgery 2024-08-28

Abstract The Ideological instruction work is related to the future and destiny of socialism with Chinese characteristics. arrival big data era has brought opportunities challenges this arduous glorious cause. combination science technology represented by data, Internet, cloud computing Internet things will inevitably lead a new round innovation development. Through questionnaire survey, in-depth interview literature analysis, paper finds out main problems college students’ network in era. we...

10.1088/1742-6596/1852/3/032034 article EN Journal of Physics Conference Series 2021-04-01

Parenchymal hemorrhage (PH) is a troublesome complication after endovascular treatment (EVT).To investigate the incidence, independent predictors, and clinical impact of PH EVT in patients with acute ischemic stroke (AIS) due to anterior circulation large vessel occlusion (LVO).Subjects were selected from ANGEL-ACT Registry. was diagnosed according European Collaborative Acute Stroke Study classification. Logistic regression analyses performed determine predictors PH, as well association...

10.1136/neurintsurg-2021-018292 article EN Journal of NeuroInterventional Surgery 2022-01-12

A need exists to better understand how racial/ethnic minority students' critical consciousness development in response marginalization may be involved their educational and career development. We therefore examined the link between decision self‐efficacy outcome expectations among community college students. Following social cognitive theory's conceptual pillars, we developed a testable model integrating variables. This was tested with 135 racially ethnically diverse Data analysis included...

10.1002/cdq.12238 article EN The Career Development Quarterly 2020-12-01
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