Changchun Jiang
A5071780771- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Neurological Disease Mechanisms and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Parkinson's Disease Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Genomics, phytochemicals, and oxidative stress
- Vascular Procedures and Complications
- Ecology and Vegetation Dynamics Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Vascular Malformations Diagnosis and Treatment
- Elbow and Forearm Trauma Treatment
- Cardiovascular Health and Disease Prevention
- Adaptive optics and wavefront sensing
- Aortic Thrombus and Embolism
- Traditional Chinese Medicine Analysis
- Drilling and Well Engineering
- Circular RNAs in diseases
- Genetic Neurodegenerative Diseases
- Cerebral Venous Sinus Thrombosis
Baotou Central Hospital
2016-2025
Inner Mongolia Medical University
2021-2025
Putian University
2024
Institute of Optics and Electronics, Chinese Academy of Sciences
2022
Zhejiang Normal University
2022
Weatherford College
2021
Inner Mongolia Comprehensive Disease Prevention and Control Center
2021
Army Medical University
2015
Affiliated Hospital of Qingdao University
2015
Qingdao University
2015
In acute ischemic stroke, there is uncertainty regarding the benefit and risk of administering intravenous alteplase before endovascular thrombectomy.We conducted a trial at 41 academic tertiary care centers in China to evaluate thrombectomy with or without patients stroke. Patients stroke from large-vessel occlusion anterior circulation were randomly assigned 1:1 ratio undergo alone (thrombectomy-alone group) preceded by alteplase, dose 0.9 mg per kilogram body weight, administered within...
The role of endovascular therapy for acute stroke with a large infarction has not been extensively studied in differing populations. Download PDF the Research Summary. We conducted multicenter, prospective, open-label, randomized trial China involving patients large-vessel occlusion anterior circulation and an Alberta Stroke Program Early Computed Tomography Score 3 to 5 (range, 0 10, lower values indicating larger infarction) or infarct-core volume 70 100 ml. Patients were randomly assigned...
The effects and risks of endovascular thrombectomy 6 to 24 hours after stroke onset due basilar-artery occlusion have not been extensively studied.
Background and Purpose— Although recent trials have suggested that stenting is worse than medical therapy for patients with severe symptomatic intracranial atherosclerotic stenosis, it not clear whether this conclusion applies to a subset of hypoperfusion symptoms. To justify new trial in China, we performed multicenter prospective registry study evaluate the safety efficacy endovascular within 30 days stenosis. Methods— Patients stenosis caused by 70% 99% combined poor collaterals were...
Importance Endovascular therapy (EVT) demonstrated better outcomes compared with medical management in recent randomized clinical trials (RCTs) of patients large infarct. Objective To compare EVT vs across different strata the Alberta Stroke Program Early Computed Tomography Score (ASPECTS) and infarct core volume Design, Setting, Participants This prespecified secondary analysis subgroups Therapy Acute Anterior Circulation Large Vessel Occlusive Patients With a Infarct Core (ANGEL-ASPECT)...
This study delves into the effects of mindfulness on workplace spirituality, work-life balance, and perceived professional benefits among nurses operating in high-pressure environments hospitals Jiangxi Province, China. Utilizing a robust sample 303 valid questionnaires employing partial least squares (PLS) analysis, research uncovers significant positive relationship between spirituality. Furthermore, it demonstrates how both spirituality balance serve as crucial mediators enhancing nurses’...
A multicentre prospective registry study of individually tailored stenting for a patient with symptomatic intracranial atherosclerotic stenosis (ICAS) combined poor collaterals in China showed that the short-term safety and efficacy was acceptable. However, it remained uncertain whether low event rate could be long term. We reported 1-year outcome this to evaluate long-term patients severe ICAS collaterals.Patients caused by 70%-99% located at internal carotid, middle cerebral, vertebral or...
Background: Delayed encephalopathy after acute carbon monoxide (CO) poisoning (DEACMP) commonly occurs recovering from CO poisoning. This study was performed to assess the efficacy of combined application dexamethasone and hyperbaric oxygen (HBO) therapy in patients with DEACMP. Patients methods: A total 120 DEACMP were recruited randomly assigned into experimental group (receiving 5 mg/day or 10 plus HBO therapy) control (HBO as monotherapy). Meanwhile, conventional treatments provided for...
The outcome of deploying balloon-mounted stents for symptomatic intracranial atherosclerotic stenosis (ICAS) has not been fully investigated. In this study we evaluate the safety and long-term using to treat ICAS in comparison with WEAVE/WOVEN study. a multicenter registry stenting artery China, 159 patients treated an stent approved by China Food Drug Administration were evaluated. morphological features lesions categorized Mori classification. endpoints, including periprocedural clinical...
Background To evaluate the prognostic effect of endovascular treatment (EVT) in patients with acute base artery occlusion (ABAO) within 24 h onset, and analyze factors related to prognosis.
Abstract Objectives Ataxia is a common symptom in patients with Cerebellar subtype of Multiple system atrophy (MSA-C), but effective treatments remain elusive. The present study aims to investigate whether repetitive transcranial magnetic stimulation (rTMS) over the bilateral cerebellum could relieve ataxia MSA-C. Patients and methods This single-center, randomized double-blind trial. 26 MSA-C were randomly divided into experimental group control group. underwent both for 10 consecutive...
BACKGROUND: The outcomes of endovascular therapy (EVT) across sexes for large infarcts remain unclear. This study aimed to evaluate the impact sex on EVT or medical management patients with infarcts. METHODS: In this secondary analysis ANGEL-ASPECT (Endovascular Therapy in Acute Anterior Circulation Large Vessel Occlusive Patients With a Infarct Core) randomized controlled trial conducted at 46 stroke centers China between October 2, 2020, and May 18, 2022, we compared baseline...
BACKGROUND:Delayed encephalopathy after acute carbon monoxide (CO) poisoning (DEACMP) is one of the most serious complications CO poisoning. This study was conducted to explore efficacy combined application N-Butylphthalide and hyperbaric oxygenation therapy (HBO) on cognitive dysfunction in patients with DEACMP. MATERIAL AND METHODS:A total 184 DEACMP were randomly assigned either receive HBO or HBO. Meanwhile, all received conventional treatment. The remission rate (RR) used assess...
BackgroundEndovascular therapy (EVT) was demonstrated effective in acute large vessel occlusion (LVO) with infarction. Revealing subgroups of patients who would or not benefit from EVT will further inform patient selection for EVT.MethodsThis post-hoc analysis the ANGEL-ASPECT trial, a randomised controlled trial 456 adult anterior-circulation LVO and infarction, defined by ASPECTS 3–5 infarct core volume 70–100 mL, enrolled 46 centres across China, between October 2, 2020 May 18, 2022....
Background and purpose 5 recent trials have shown the benefit of endovascular treatment for acute ischaemic stroke (AIS) due to large vessel occlusion anterior circulation. This study aims evaluate safety efficacy Solitaire thrombectomy in patients with moderate-to-severe Chinese population, which has a high prevalence intracranial atherosclerosis. Methods analysis multicentre prospective control will involve 17 centres China, plans recruit 150 intervention group, medical meet enrolment...
“Interspecific associations” refers to the interrelationship among different species in a particular spatial distribution, which plays an important role community assembly, and responses environmental changes. However, strength and/or direction of interspecific associations may vary with gradients scales. To understand effects habitat types research scales on subtropical forests, we modeled for more than 15,000 individuals representing 74 co-occurring from three by using variance ratio...
Hyperperfusion (HP) is a devastating complication associated with carotid artery stenting (CAS) or endarterectomy. The efficacy and safety of staged angioplasty (SAP) in patients CAS at high risk HP remains unclear. We sought to determine whether SAP superior regular HP. A randomised, multicentre open-label clinical trial blinded outcome assessment (STEP) was conducted. Patients severe stenosis were randomly assigned (1:1) the group. primary endpoint hyperperfusion syndrome (HPS)...
The recent randomized controlled trials studying intracranial atherosclerotic stenosis (ICAS) have used digital subtraction angiography (DSA) to quantify and enroll patients. However, some disadvantages of DSA such as invasive features, contrast agent overuse, X-ray radiation overexposure, were not considered in these studies. This study aimed explore whether computed tomography (CTA) with semi-automatic analysis could be an alternative method quantifying the absolute stenotic degree clinical trials.
The aim of this study was to investigate the correlation between aortic/carotid atherosclerotic plaques and cerebral infarction. We examined 116 cases infarction using transcranial Doppler ultrasound in order exclude cerebrovascular stenosis. Transesophageal echocardiography color were used detect aortic (AAPs) carotid (CAPs). AAPs detected a total 70 (60.3%), including 56 with moderate/severe changes (48.3%). difference incidence various types APP severity levels significant (P<0.01). Of...