A5019910065- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Meningioma and schwannoma management
- Intracerebral and Subarachnoid Hemorrhage Research
- Stroke Rehabilitation and Recovery
- Spinal Fractures and Fixation Techniques
- Radiation Dose and Imaging
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced X-ray and CT Imaging
- Neurosurgical Procedures and Complications
- Venous Thromboembolism Diagnosis and Management
- Cerebrospinal fluid and hydrocephalus
- Spine and Intervertebral Disc Pathology
- Peripheral Artery Disease Management
- Brain Metastases and Treatment
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Anesthesia and Pain Management
- Glioma Diagnosis and Treatment
- Moyamoya disease diagnosis and treatment
- Cerebral Venous Sinus Thrombosis
- Pelvic and Acetabular Injuries
- Neurological and metabolic disorders
Karolinska University Hospital
2015-2024
Karolinska Institutet
2015-2024
Alberta Bible College
2019
Taipei Veterans General Hospital
2005-2018
National University Health System
2018
National University of Singapore
2018
Hospital Ruber Internacional
2018
National University Hospital
2018
Suzuki (Japan)
2018
World Federation for Mental Health
2016
Prospective observational study.The aim of this study was to evaluate the accuracy pedicle screw placement using augmented reality surgical navigation (ARSN) in a clinical trial.Recent cadaveric studies have shown improved for thoracic spine ARSN with intraoperative 3D imaging, without need periprocedural x-ray. In study, we used same system place screws and lumbosacral 20 patients.The performed hybrid operating room an integrated encompassing table, motorized flat detector C-arm 2D/3D...
Dural arteriovenous shunts with cortical venous reflux or drainage may cause neurological symptoms and death without intracranial hemorrhage. Present knowledge about the natural history of these lesions is limited, however. We investigated incidences hemorrhage, progressive dementia syndrome, in patients diagnosed our neurovascular center.We evaluated records 85 dural hospitalized institution from 1978 to 2007. The annual were calculated.Fifty-three did not have an hemorrhage as presenting...
A cadaveric laboratory study.The aim of this study was to assess the feasibility and accuracy thoracic pedicle screw placement using augmented reality surgical navigation (ARSN).Recent advances in spinal have shown improved lumbosacral but limited benefits spine. 3D intraoperative imaging instrument may allow placement, without use x-ray fluoroscopy, thus opens route image-guided minimally invasive therapy spine.ARSN encompasses a table, motorized flat detector C-arm with 2D/3D capabilities,...
Cadaveric laboratory study.To assess the feasibility and accuracy of minimally invasive thoracolumbar pedicle screw placement using augmented reality (AR) surgical navigation.Minimally spine (MIS) surgery has increasingly become method choice for a wide variety pathologies. Navigation technology based on AR been shown to be feasible, accurate, safe in open procedures. may also used MIS surgery.The navigation was installed hybrid operating room (OR). The OR includes table, motorized flat...
Object The authors describe the first clinical trial with encapsulated cell biodelivery (ECB) implants that deliver nerve growth factor (NGF) to cholinergic basal forebrain intention of halting degeneration neurons and associated cognitive decline in patients Alzheimer disease (AD). NsG0202 implant (NsGene A/S) consists an NGF-producing, genetically engineered human line behind a semipermeable hollow fiber membrane allows influx nutrients efflux NGF. centimeter-long capsule is attached inert...
To test the hypothesis that an image noise reduction algorithm designed for digital subtraction angiography (DSA) in interventional neuroradiology enables a patient entrance dose by factor of 4 while maintaining quality.This clinical prospective study was approved local ethics committee, and all 20 adult patients provided informed consent. DSA performed with default reference program, quarter-dose program modified acquisition parameters (to reduce radiation exposure), real-time...
Dural arteriovenous fistulas (DAVFs) of the anterior cranial fossa are rare lesions that can cause intracranial hemorrhage. Authors previous reports mostly have described open surgical treatment for this fistula type. The authors' purpose in present study was to describe their experience with DAVFs, including endovascular treatment.All patients DAVFs diagnosed and treated 3 separate institutions during last 23 years were retrospectively identified. Clinical charts, imaging studies,...
✓ One suprasellar, one mesencephalic, and nine cerebellar hemangioblastomas were treated with the gamma knife in 10 patients (median age 48 years) Stockholm between 1978 1993. Four had von Hippel—Lindau disease, a dominant inherited trait predisposing to multiple hemangioblastomas. Six radiotherapy at median margin dose of 25 Gy (20–35 Gy) before 1990 next five (5–19 Gy). Computerized tomography or magnetic resonance images available for 11 follow-up time 26 months (4–68 months) after...
Object The aim of this study was to assess the clinical efficacy gamma knife surgery (GKS) in treatment dural arteriovenous shunts (DAVSs). Methods From a database more than 1600 patients with intracranial that had been treated GKS, authors retrospectively and prospectively identified 53 58 DAVSs from period between 1978 2003. Four were lost follow-up evaluation excluded series. Thus, is based on remaining 49 52 DAVSs. Thirty-six drained into cortical venous system, either directly or...
Object The aim of this study was to analyze factors influencing survival time and patterns distant recurrences after Gamma Knife surgery (GKS) for metastases the brain. Methods Information available 1855 1921 patients who underwent GKS single or multiple cerebral at 4 different institutions during periods between 1975 2007. total number treatments administered 2448, an average 1.32 per patient. median analyzed, related patient treatment parameters, compared with published data following...
The purpose of this study was to quantify the reduction in patient radiation dose by X-ray imaging technology using image noise and system settings for neuroangiography assess its impact on working habits physician.Radiation data from 190 neuroangiographies 112 interventional neuroprocedures performed with state-of-the-art processing reference were collected period January-June 2010. then configured extra algorithms settings, which enabled without loss quality. Radiation 174 138 2012....
Prospective observational study.To assess staff and patient radiation exposure during augmented reality surgical navigation in spine surgery.Surgical combination with intraoperative three-dimensional imaging has been shown to significantly increase the clinical accuracy of pedicle screw placement. Although this technique may total compared fluoroscopy, occupational can be minimized, as is free positioned behind protective shielding imaging. The treatment verification positions also...
Objective To report our preliminary experience with the use of stent retrievers to cause vasodilation in patients delayed cerebral vasospasm secondary subarachnoid hemorrhage. Methods Four from two different high volume neurointerventional centers developed following In addition standard techniques for treatment vasospasm, we used commercially available (Solitaire and Capture retrievers) treat vasospastic segment including M2, M1, A2, A1. We evaluated safety this technique, degree...
OBJECTIVE: To study the results after fractionated radiotherapy of large arteriovenous malformations (AVMs). METHODS: Twenty-eight patients harboring AVMs were treated between 1980 and 1985 with up to 3.5 Gy per fraction twice a week total dose 41 50 Gy. All but 5 examined an angiogram at least 4 years treatment. RESULTS: Two (8%) obliterated Eight died: five as result hemorrhages, two unknown causes, one lung carcinoma. Five deteriorated slightly, three moderately, four severely The longer...
Background Most studies of the treatment for acute basilar occlusion focus on intravenous or intra-arterial thrombolysis whereas data mechanical thrombectomy as preferred are scarce. In this study, presented 28 patients treated with artery occlusion. Methods Retrospective study comprising all who were at Karolinska University Hospital from September 2005 to November 2010. Favorable outcome was defined a modified Rankin score ≤2 3–8 months after thrombectomy. Results Of thrombectomy,...
Background Emergency stent placement in the extracranial internal carotid artery combination with anterior circulation thrombectomy is a routine procedure. Yet, precise indications and clinical safety this setting remains controversial. Present data for mechanical include few studies acute stenting of tandem occlusions. We evaluated feasibility, outcome endovascular treatment retrospective analysis all consecutive cases at comprehensive stroke centre. Methods This was patients occlusion...
Background and purpose Intrasaccular aneurysm flow disruption represents an emerging endovascular approach to treat intracranial aneurysms. The of this study was determine the clinical angiographic outcomes using LUNA embolization system (AES) for treatment Materials methods AES Post-Market Clinical Follow-Up is a prospective, multicenter, single-arm that designed evaluate device safety efficacy. Bifurcation sidewall aneurysms were included. Aneurysm occlusion assessed Raymond-Roy...