A5072737686- Radiation Dose and Imaging
- Cancer Risks and Factors
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Testicular diseases and treatments
- Multiple and Secondary Primary Cancers
- Lymphoma Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Assisted Reproductive Technology and Twin Pregnancy
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal and Anal Carcinomas
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Renal Transplantation Outcomes and Treatments
- Effects of Radiation Exposure
- Medical Imaging Techniques and Applications
- Neonatal Respiratory Health Research
- Esophageal Cancer Research and Treatment
- Venous Thromboembolism Diagnosis and Management
- Ultrasound in Clinical Applications
- Maternal and Perinatal Health Interventions
- Stroke Rehabilitation and Recovery
- Childhood Cancer Survivors' Quality of Life
Karolinska Institutet
2015-2025
Karolinska University Hospital
2016-2025
University of Lausanne
2023
Yale University
2023
KTH Royal Institute of Technology
2023
École Polytechnique Fédérale de Lausanne
2023
Linköping University
2023
National Cancer Institute
2006-2013
University of Iowa
2006-2013
Cancer Registry of Norway
2006-2008
Although second primary cancers are a leading cause of death among men with testicular cancer, few studies have quantified risks long-term survivors.Within 14 population-based tumor registries in Europe and North America (1943-2001), we identified 40,576 1-year survivors cancer ascertained data on any new incident solid tumors these patients. We used Poisson regression analysis to model relative (RRs) excess absolute (EARs) cancers. All statistical tests were two-sided.A total 2,285 reported...
Undescended testis, which is a risk factor for testicular cancer, usually treated surgically, but whether the age at treatment has any effect on unclear. We studied relation between undescended testis and of cancer.We identified men who underwent orchiopexy in Sweden 1964 1999. Cohort subjects were Swedish Hospital Discharge Register followed occurrence cancer through Cancer Registry. Vital statistics data migration status taken from Population Changes years 1965 2000. estimated relative...
Hodgkin's lymphoma (HL) survivors are known to be at substantially increased risk of solid cancers (SC). However, no investigation has used multivariate modeling estimate the relative (RR), excess absolute (EAR), and cumulative incidence for specific attained ages HL diagnosis.We identified 18,862 5-year from 13 population-based cancer registries in North America Europe. Poisson regression was evaluate effects age diagnosis, age, latency, sex, treatment, year diagnosis on RR EAR SC.Among...
BackgroundGiven the extended survival of patients diagnosed with cervical cancer, large number these women treated radiotherapy, and presence in this population established cancer risk factors such as human papillomavirus (HPV) infection cigarette smoking, it is important to clarify long-term trends second risk.
Over one million European children undergo computed tomography (CT) scans annually. Although moderate- to high-dose ionizing radiation exposure is an established risk factor for hematological malignancies, risks at CT examination dose levels remain uncertain. Here we followed up a multinational cohort (EPI-CT) of 948,174 individuals who underwent examinations before age 22 years in nine countries. Radiation doses the active bone marrow were estimated on basis body part scanned, patient...
Although modern treatments for testicular cancer are associated with increased survival, the long-term health effects of these unclear. We conducted a population-based study to quantify risks mortality from noncancer causes among men cancer.We identified 38,907 one-year survivors within 14 registries in North America and Europe (from 1943 through 2002). used data calculate standardized ratios (SMRs) deaths evaluate associations between histology, age at diagnosis, calendar year initial...
Several studies have reported an association between low birth weight and ischemic heart disease, but it remains unclear whether the is mediated through poor fetal growth or short gestational duration.In a cohort study, we identified all subjects born preterm with at 4 major delivery units in Sweden from 1925 1949. For comparison, equal number of none these criteria were within same source population. The study population consists 6425 subjects, whom 2931 before 37 weeks gestation 2176 had <...
Low birth weight is consistently associated with an increased risk of type 2 diabetes in adulthood, but the individual contributions from poor fetal growth and preterm are not known. We therefore investigated significance these two factors separately.We identified a cohort subjects born or low at term four major delivery units Sweden 1925 through 1949. A comparison was same source population. Of 6,425 all, 2,931 were <37 weeks gestation 2,176 had <2,500 g. Disease occurrence among...
Treatment-related stomach cancer is an important cause of morbidity and mortality among the growing number Hodgkin lymphoma (HL) survivors, but risks associated with specific HL treatments are unclear.
In epidemiologic studies of perinatal exposures, birth weight has been proposed as a proxy variable for intrauterine estrogen exposure. To assess the validity this assumption, we performed analyses association between estriol levels in 188 women 17th, 25th, 33rd, and 37th weeks pregnancy weights their infants. We found general increase mean cumulative dose with increasing category throughout pregnancy. late pregnancy, level mothers infants highest (>4,500 gm) was twice high that lowest...
Few studies have examined long-term suicide risk among breast cancer survivors, and there are no data for women in the United States. We quantified through 2002 723 810 1-year survivors diagnosed between January 1, 1953, December 31, 2001, reported to 16 population-based registries States Scandinavia. Among we calculated standardized mortality ratios (SMRs) excess absolute risks (EARs) compared with general population, probability of suicide. used Poisson regression likelihood ratio tests...
Why was the cohort set up?Medical diagnostic examinations, although delivering low doses of ionizing radiation, are main man-made source radiation exposure for general population.The number procedures performed has grown dramatically in high-income countries recent decades. 1 Among
Abdominal radiotherapy for testicular cancer (TC) increases risk second stomach cancer, although data on the radiation dose-response relationship are sparse.
Computed tomography (CT) has great clinical utility and its usage increased dramatically over the years. Concerns have been raised, however, about health impacts of ionising radiation exposure from CTs, particularly in children, who a higher risk for some induced diseases. Direct estimation impact these exposures is needed, but conduct epidemiological studies paediatric CT populations poses number challenges which, if not addressed, could invalidate results.
Background Hearing loss and tinnitus have been proposed as potential indicators of impaired mental health brain morphological changes. Aims To assess the associations hearing with risk depression anxiety volume. Method We conducted a community-based cohort study including 129 610 participants aged 40−69 years at recruitment to UK Biobank follow-up period during 2006–2021 estimate after detection reported tinnitus. also assessed volume in subsample available magnetic resonance imaging data (...
Treatments for Hodgkin lymphoma are associated with large relative risks of acute myeloid leukemia (AML), but there few estimates the excess absolute risk (EAR), a useful measure disease burden. One-year survivors (N = 35,511) were identified within 14 population-based cancer registries in Nordic countries and North America from January 1, 1970, through December 31, 2001. We used Poisson regression analysis to model EAR AML, per 10,000 person-years. A total 217 diagnosed AML (10.8 expected;...
Although cervical squamous cell carcinoma (SCC) and adenocarcinoma (AC) are both caused by human papillomavirus (HPV) infection, they differ in cofactors such as cigarette smoking. We assessed whether these cofactor differences translate into second cancer risk.We risk among 85,109 SCC 10,280 AC survivors reported to population-based registries Denmark, Finland, Norway, Sweden, the United States. Risks compared general population were using standardized incidence ratios (SIR).Overall was...
Abstract Objective. To assess the risk for emergency cesarean section among women in whom labor was induced gestational week ≥41 and to evaluate if parity mode of induction affected this association. Design. Hospital‐based retrospective cohort study. Population . Singleton pregnancies delivered after weeks at Danderyd Hospital, Stockholm, Sweden, during 2002–2006. Material methods. Of 23 030 singleton meeting entry criteria, 881 were with a Bishop score <7. Obstetric outcome assessed...
Background Most studies of the treatment for acute basilar occlusion focus on intravenous or intra-arterial thrombolysis whereas data mechanical thrombectomy as preferred are scarce. In this study, presented 28 patients treated with artery occlusion. Methods Retrospective study comprising all who were at Karolinska University Hospital from September 2005 to November 2010. Favorable outcome was defined a modified Rankin score ≤2 3–8 months after thrombectomy. Results Of thrombectomy,...