Joshua S. Catapano
A5004308347- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Neurosurgical Procedures and Complications
- Meningioma and schwannoma management
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Moyamoya disease diagnosis and treatment
- Cerebrospinal fluid and hydrocephalus
- Spinal Fractures and Fixation Techniques
- Vascular Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Peripheral Artery Disease Management
- Central Venous Catheters and Hemodialysis
- Stroke Rehabilitation and Recovery
- Surgical Simulation and Training
- Head and Neck Surgical Oncology
- Venous Thromboembolism Diagnosis and Management
- Vascular Anomalies and Treatments
- Spinal Dysraphism and Malformations
- Cardiac, Anesthesia and Surgical Outcomes
- Spinal Hematomas and Complications
- Trigeminal Neuralgia and Treatments
- Neurological Complications and Syndromes
St. Joseph's Hospital and Medical Center
2017-2025
Barrow Neurological Institute
2016-2025
University of Pennsylvania
2024-2025
University at Buffalo, State University of New York
2025
Phoenix (United States)
2024
Neurological Surgery
2019-2023
Barber-Nichols (United States)
2020-2023
American Association of Neurological Surgeons
2021
Society for Minimally Invasive Spine Surgery
2021
University of Southern California
2019-2020
Cerebrovascular diseases are a leading cause of death and neurologic disability. Further understanding disease mechanisms therapeutic strategies requires deeper knowledge cerebrovascular cells in humans. We profiled transcriptomes 181,388 to define cell atlas the adult human cerebrovasculature, including endothelial molecular signatures with arteriovenous segmentation expanded perivascular diversity. By leveraging this reference, we investigated cellular perturbations brain malformations,...
Background and Purpose- The CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) demonstrated equivalent composite outcomes between carotid endarterectomy (CEA) artery stenting (CAS) for treating stenosis. We investigated nationwide trends in these procedures associated periprocedural stroke, myocardial infarction, death, cost, readmission rates since were published. Methods- queried the Nationwide Readmissions Database to identify patients undergoing CEA CAS asymptomatic...
Background The transradial artery (TRA) approach for neuroendovascular procedures continues to gain popularity, but neurointerventionalists still lag behind interventional cardiologists in the adoption of a TRA-first approach. This study compares complications and efficiency TRA standard transfemoral (TFA) at our institution during initial phase adopting Methods A retrospective analysis was performed on all consecutive neuroangiographic large cerebrovascular center from October 1, 2018 June...
Background Recently, middle meningeal artery (MMA) embolization has emerged as a potentially safe and effective method of treating chronic subdural hematoma (cSDH). Objective To report single-center experience with MMA examines the type embolic material used, extent penetration, number branches embolized. Methods A retrospective analysis all patients from 2018 through 2019 was performed. failed outcome defined either surgical rescue and/or greater than 10 mm residual or reaccumulation...
Traumatic brain injury (TBI) heterogeneity remains a critical barrier to translating therapies. Identifying final common pathways/molecular signatures that integrate this informs biomarker and therapeutic-target development. We present the first large-scale murine single-cell atlas of transcriptomic response TBI (334,376 cells) across clinically relevant models, sex, region, time as foundational step in molecularly deconstructing heterogeneity. Results were unique cell populations, regions,...
OBJECTIVE Middle meningeal artery (MMA) embolization is a promising treatment strategy for chronic subdural hematomas (cSDHs). However, studies comparing MMA and conventional therapy (surgical intervention conservative management) are limited. The authors aimed to compare versus cSDHs using propensity-adjusted analysis. METHODS A retrospective study of all patients with cSDH who presented large tertiary center over 2-year period was performed. compared surgical management. Neurological...
Background Chronic subdural hematoma is associated with high rates of perioperative complications and recurrence. Methods The classic treatments are observation or surgical evacuation. Middle meningeal artery embolization a recently emerging procedure that has evolved as the neuroendovascular community gained collective experience. This review summarizes pathophysiology chronic hematoma, reviews treatment strategies, discusses advent use middle embolization, describes contemporary technical...
Background The Woven EndoBridge (WEB) device is frequently used for the treatment of intracranial aneurysms. Postoperative management, including use aspirin, varies among clinicians and institutions, but its impact on outcomes WEB has not been thoroughly investigated. Methods This was a retrospective, multicenter study involving 30 academic institutions in North America, South Europe. Data from 1492 patients treated with were included. Patients categorized into two groups based their...
BACKGROUND AND OBJECTIVES: Microsurgical aneurysm repair by clipping continues to be highly important despite increasing endovascular treatment options, especially because of inferior occlusion rates. This study aimed present current global microsurgical practices and identify risk factors for complications neurological deterioration after unruptured anterior circulation aneurysms. METHODS: Fifteen centers from 4 continents participated in this retrospective cohort study. Consecutive...
Abstract Objectives Approximately 30% of patients with subarachnoid hemorrhage (SAH) present multiple aneurysms. Identifying the ruptured aneurysm is often difficult, and not all lesions may be accessible through a single craniotomy. Magnetic resonance high-resolution vessel wall imaging (HR-VWI) an innovative modality that identifies instability. Design Technical note literature review illustrative case report operative videos. Setting Outpatient, inpatient, operating room quaternary...
BACKGROUND: The Woven EndoBridge (WEB) device (Terumno Corp. [parent company of Microvention]) was approved by the U.S. Food and Drug Administration as first intrasaccular for intracranial aneurysm treatment in December 2018. Its use has become more common since then, but both trial results postmarket experiences have raised questions about efficacy achieving complete obliteration. Retreatment after WEB embolization not been extensively discussed. OBJECTIVE: To discuss incidence retreatment...
Racial and socioeconomic health disparities are well documented in the literature. This study examined patient demographics, including status (SES), among individuals presenting with aneurysmal subarachnoid hemorrhage (aSAH) unruptured intracranial aneurysm (UIA) to identify factors associated aSAH presentation. A retrospective assessment was conducted of all patients UIA who presented a large-volume cerebrovascular center underwent microsurgical treatment from January 2014 through July...
OBJECTIVE Tobacco smoking is among the factors known to significantly augment risk of untreated intracranial aneurysm (IA) growth and rupture. Smoking appears have a variable effect on different endovascular treatment modalities. The impact safety, efficacy, outcomes Woven EndoBridge (WEB) device use for wide-neck IAs has not been evaluated. This study aimed investigate WEB devices by status. METHODS A retrospective multicenter analysis was conducted data patients from 36 sites worldwide...
Background Intracranial atherosclerotic disease (ICAD) is a leading cause of stroke, often refractory to aggressive medical therapy. Recent advancements in drug-eluting stents (DES) show promise for improved efficacy intracranial applications relative traditional ICAD treatments. Methods We retrospectively collected all consecutive deployments the Onyx Frontier [Medtronic, Santa Rosa, CA] stent setting between August 2022 and 2024 at six high-volume neuro-interventional centers across US....
OBJECTIVE Blister aneurysms of the internal carotid artery (ICA) have high associated mortality rates and are challenging due to their friable wall poorly defined neck. Microsurgical endovascular treatment options been suggested, including bypass parent vessel exclude aneurysm. The goal this study was evaluate safety efficacy microsurgical versus interventions. Additionally, for patients treated with open surgery, outcomes were compared nonbypass techniques. METHODS Three databases...
Abstract The Woven EndoBridge (WEB) device is FDA-approved for the treatment of bifurcation aneurysms. Despite its wide popularity, it has been under scrutiny association with potential aneurysm recanalization and retreatment due to shape modification. This study aims analyze modification rate WEB devices identify factors associated this phenomenon, as well correlation retreatment. We conducted a retrospective review WorldWide Consortium database, including adult patients treated...
Posterior reversible encephalopathy syndrome is a multifactorial neurological disorder characterized by clinical and neuroimaging findings. The “vasogenic theory” suggests that, in this condition, disrupted cerebrovascular autoregulation leads to blood‐brain barrier failure vasogenic edema. commonly associated with hypertension, chemotherapy, transplantation, but neurosurgical patients, including those undergoing digital subtraction angiography, are also at elevated risk. A patient history...
INTRODUCTION: Thromboelastography (TEG) is a routine, relatively inexpensive blood test that measures the coagulative properties of sample. Previous studies have demonstrated its efficacy in predicting coagulation profiles patients with subarachnoid hemorrhage (SAH), however, relationship to neurological presentation and clinical outcome aneurysmal (aSAH) remains understudied. METHODS: We retrospectively identified 139 from July 2020 - September 2022 aSAH obtained TEGs without platelet...
INTRODUCTION: Blister aneurysms (BAs) of the internal carotid artery (ICA) have high associated mortality and are challenging owing to their friable wall poorly defined neck. Microsurgical endovascular treatment options been suggested, including bypass parent vessel exclude aneurysm. METHODS: Three databases were queried for primary studies comparing microsurgery therapy BAs ICA. All relevant published between 2000 2023 eligible inclusion. The following data points extracted from each study:...
INTRODUCTION: Pediatric brainstem cavernous malformations (BSCMs) pose challenges due to the lack of standardized management guidelines. Microsurgical resection has shown increasing promise; however, postoperative course pediatric BSCMs not been extensively documented because rarity these lesions and difficulty microsurgical resection. METHODS: We retrospectively studied 693 patients who underwent surgery for a BSCM between 1984 2023 at three institutions (620 adult, 73 pediatric). Data...
INTRODUCTION: Blister aneurysms (BAs) of the internal carotid artery (ICA) have high associated mortality and are challenging owing to their friable wall poorly defined neck. Microsurgical treatment options been suggested, including bypass parent vessel exclude aneurysm. METHODS: Three databases were queried for relevant studies published between 2000 2023. The following primary data points extracted from each study: specific therapy employed, complications, postoperative functional status...
BACKGROUND Extra-axial cavernous malformations (CMs) in the cerebellopontine angle (CPA) are rare, typically affect cranial nerves (CNs), and present significant therapeutic challenges. This report discusses case of a patient with an extra-axial CM CPA involving CN VII/VIII complex, alongside systematic review similar cases. OBSERVATIONS A literature search PubMed Embase databases identified 216 articles, 18 meeting inclusion criteria, encompassing 21 cases (average age 42.6 years). The most...