- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Moyamoya disease diagnosis and treatment
- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Cerebral Venous Sinus Thrombosis
- Aortic Disease and Treatment Approaches
- Neurosurgical Procedures and Complications
- Advanced MRI Techniques and Applications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrospinal fluid and hydrocephalus
- Medical Imaging and Analysis
- Coronary Interventions and Diagnostics
- Congenital Heart Disease Studies
- Cardiovascular Health and Disease Prevention
- Meningioma and schwannoma management
- Blood Coagulation and Thrombosis Mechanisms
- Vascular Procedures and Complications
- Spinal Fractures and Fixation Techniques
Prisma Health
2019-2024
University of South Carolina
2024
Jordan Hospital
2024
Health and Education Research Management and Epidemiologic Services (United States)
2023
Greenville Memorial Hospital
2023
LMU Klinikum
2022
Ludwig-Maximilians-Universität München
2022
Proteogenomics Research Institute for Systems Medicine
2021
Prisma
2021
Medical University of South Carolina
2011-2020
Background The development of new revascularization devices has improved recanalization rates and time, but not clinical outcomes. We report a prospectively collected experience with technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization. Methods 98 identified acute ischemic stroke patients 100 occluded cerebral vessels at six institutions were included in study. ADAPT was utilized all patients. Procedural data captured analysis....
The development of new revascularization devices has improved recanalization rates and time, but not clinical outcomes. We report a prospectively collected experience with technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization.98 identified acute ischemic stroke patients 100 occluded cerebral vessels at six institutions were included in study. ADAPT was utilized all patients. Procedural data captured analysis.The component alone...
Background The development of new revascularization devices has improved recanalization rates and time but not clinical outcomes. We report our initial results with a technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization. Methods A retrospective evaluation prospectively captured database 37 patients at six institutions was performed on where ADAPT utilized. data represent experience this technique. Results alone successful in 28...
Background and Purpose— The current report details our initial periprocedural experience with Wingspan (Boston Scientific/Target), the first self-expanding stent system designed for treatment of intracranial atheromatous disease. Methods— All patients undergoing angioplasty stenting Gateway balloon–Wingspan were prospectively tracked. Results— During a 9-month period, was attempted in 78 (average age, 63.6 years; 33 women) 82 lesions, which 54 ≥70% stenotic. Eighty-one lesions successfully...
The development of new revascularization devices has improved recanalization rates and time but not clinical outcomes. We report our initial results with a technique utilizing direct aspiration first pass large bore catheter as the primary method for vessel recanalization.A retrospective evaluation prospectively captured database 37 patients at six institutions was performed on where ADAPT utilized. data represent experience this technique.The alone successful in 28 (75%) cases although had...
Objective Flexible large lumen aspiration catheters and stent retrievers have recently become available in the USA for revascularization of vessel occlusions presenting within context acute ischemic stroke (AIS). We describe a multicenter experience using combined retrieval technique thrombectomy. Design A retrospective analysis to identify patients receiving manual treatment AIS between August 2012 April 2013 at six high volume centers was conducted. Outcome variables, including...
OBJECTIVE Wingspan (Boston Scientific, Fremont, CA) is a self-expanding stent designed specifically for the treatment of symptomatic intracranial atheromatous disease. The current series reports observed incidence in-stent restenosis (ISR) and thrombosis on angiographic follow-up. METHODS A prospective, intent-to-treat registry patients in whom system was used to treat disease maintained at five participating institutions. Clinical follow-up results were recorded. ISR defined as stenosis...
<b>BACKGROUND AND PURPOSE:</b> Wingspan is a self-expanding, microcatheter-delivered microstent specifically designed for the treatment of symptomatic intracranial atherosclerotic disease. Our aim was to discuss effect patient age and lesion location on in-stent restenosis (ISR) rates after percutaneous transluminal angioplasty stenting (PTAS) with system. <b>MATERIALS METHODS:</b> Clinical angiographic follow-up results were recorded all patients from 5 participating institutions. ISR...
Background and Purpose— Patients with posterior circulation strokes have been excluded from recent randomized endovascular stroke trials. We reviewed the multicenter experience treatment of to identify clinical, radiographic, procedural predictors successful recanalization good neurological outcomes. Methods— performed a retrospective analysis consecutive patients strokes, who underwent thrombectomy stent retrievers or primary aspiration (including A Direct Aspiration First Pass Technique...
Introduction The use of mechanical thrombectomy for the treatment acute ischemic stroke has significantly advanced over last 5 years. Few data are available comparing cost and clinical angiographic outcomes associated with techniques. aim this study is to compare efficacy current endovascular therapies. Methods A single-center retrospective review was performed medical record hospital financial database all cases admitted from 2009 2013. Three discrete methodologies used during time were...
<h3>BACKGROUND AND PURPOSE:</h3> The ability of polymer-modified coils to promote stable aneurysm occlusion after endovascular treatment is not well-documented. Angiographic recurrence widely used as a surrogate for failure, but studies documenting the correlation angiographic with clinical failure are limited. This trial compares effectiveness Matrix<sup>2</sup> polyglycolic/polylactic acid biopolymer–modified bare metal and correlates findings (ie, target recurrence), composite end point...
<h3>BACKGROUND AND PURPOSE:</h3> Stent-assisted coiling may result in less aneurysm recanalization but more complications than alone. We evaluated outcomes of with and without stents the multicenter Matrix Platinum Science Trial. <h3>MATERIALS METHODS:</h3> All patients Trial unruptured intracranial aneurysms treated per protocol were included. Baseline patient characteristics, procedural details, neurologic outcomes, angiographic safety data analyzed. <h3>RESULTS:</h3> Overall, 137 361...
BACKGROUND: Stent-assisted coiling with 2 stents in a Y configuration is technique for complex wide-neck bifurcation aneurysms. OBJECTIVE: We sought to provide long-term clinical and angiographic outcomes Y-stent coiling, which are not currently established. METHODS: Seven centers provided deidentified, retrospective data on all consecutive patients who underwent stent-assisted an intracranial aneurysm configuration. RESULTS: Forty-five treatment by coiling. Their mean age was 57.9 years....
Robotic-assisted technology has been used as a tool to enhance open and minimally invasive surgeries well percutaneous coronary peripheral vascular interventions. It offers many potential benefits, including increased procedural technical accuracy reduced radiation dose during fluoroscopic procedures. also the for truly “remote” Despite these robotic not yet in neuroendovascular field, aside from diagnostic cerebral angiography. Here, we report first robotic-assisted, therapeutic,...
Outcome studies in acute ischemic stroke (AIS) have focused on time from symptom onset to treatment. The purpose of this study was investigate whether achieve vessel recanalization groin puncture affects outcomes.We studied all AIS cases that underwent intra-arterial therapy between May 2008 and October 2012 at a high volume center for anterior circulation occlusions. Candidacy thrombectomy is determined by CT perfusion imaging, irrespective onset. Patients were then dichotomized into two...
The treatment effects of individual mechanical thrombectomy devices in large-vessel acute ischemic stroke (AIS) remain unclear.To determine whether the novel 3-dimensional (3-D) stent retriever used conjunction with an aspiration-based device (Penumbra System; Penumbra) is noninferior to alone AIS.This randomized, noninferiority clinical trial enrolled patients at 25 North American centers from May 19, 2012, through November 2015, follow-up for 90 days. Adjudicators primary end points were...
Background The efficacy of endovascular thrombectomy (ET) for acute ischemic stroke (AIS) in octogenarians is still controversial. Objective To evaluate, using a large multicenter cohort patients, outcomes after ET compared with younger patients. Methods Data from prospectively maintained databases patients undergoing AIS at seven US-based comprehensive centers between January 2013 and 2018 were reviewed. Demographic, procedural, outcome variables collected. Outcomes included 90-day modified...
Background Vessel perforation during stent retriever thrombectomy is a rare complication; typically only single instances have been reported. Objective To report on series of patients whose was complicated by intraprocedural vessel and discuss its potential mechanisms, rescue treatment strategies, clinical significance. Methods Cases with perforation, where used either as primary approach or part direct aspiration first pass technique (ADAPT), were included in the final analysis. Clinical...
Acute large vessel occlusion (LVO) can result from thromboemboli or underlying intracranial atherosclerotic disease (ICAD). Although the technique for revascularization differs significantly these two lesions (simple thrombectomy and balloon angioplasty stenting ICAD), etiology is often unknown in acute ischemic stroke (AIS).To evaluate whether procedural complications, rates, functional outcomes differ among patients with LVO ICAD thromboembolism.A retrospective review of cases 2008 to 2015...
Background Blood blister aneurysms (BBA) are a rare subset of intracranial that represent therapeutic challenge from both surgical and endovascular perspective. Objective To report multicenter experience with flow diversion exclusively for BBA, located at non-branching segments along the anteromedial wall supraclinoidal internal carotid artery (ICA). Methods Consecutive cases BBA ICA treated were included in final analysis. Results 49 patients 51 devices to achieve effect identified. 43 45...