Sananthan Sivakanthan

ORCID: 0000-0003-2514-680X
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Meningioma and schwannoma management
  • Cerebrovascular and Carotid Artery Diseases
  • Spinal Fractures and Fixation Techniques
  • Spinal Dysraphism and Malformations
  • Acute Ischemic Stroke Management
  • Head and Neck Surgical Oncology
  • Spinal Cord Injury Research
  • Trauma Management and Diagnosis
  • Intracranial Aneurysms: Treatment and Complications
  • Advanced Neuroimaging Techniques and Applications
  • Cervical and Thoracic Myelopathy
  • Advanced MRI Techniques and Applications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Pituitary Gland Disorders and Treatments
  • COVID-19 and healthcare impacts
  • Surgical Simulation and Training
  • Glioma Diagnosis and Treatment
  • Spinal Hematomas and Complications
  • Fetal and Pediatric Neurological Disorders
  • Long-Term Effects of COVID-19
  • Vestibular and auditory disorders
  • Diversity and Career in Medicine
  • Trigeminal Neuralgia and Treatments
  • Facial Nerve Paralysis Treatment and Research

University of Washington
2019-2024

Neurological Surgery
2013-2024

Seattle University
2022

Seattle Children's Hospital
2022

University of South Florida
2014-2017

Capital Health
2016

Medical University of South Carolina
2016

Saint Thomas Midtown Hospital
2016

University at Buffalo, State University of New York
2016

Baylor College of Medicine
2016

Background and Purpose— Patients with posterior circulation strokes have been excluded from recent randomized endovascular stroke trials. We reviewed the multicenter experience treatment of to identify clinical, radiographic, procedural predictors successful recanalization good neurological outcomes. Methods— performed a retrospective analysis consecutive patients strokes, who underwent thrombectomy stent retrievers or primary aspiration (including A Direct Aspiration First Pass Technique...

10.1161/strokeaha.115.011598 article EN Stroke 2016-02-18

OBJECT The dentatorubrothalamic tract (DRTT) is the major efferent cerebellar pathway arising from dentate nucleus (DN) and decussating to contralateral red (RN) thalamus. Surprisingly, hemispheric output influences bilateral limb movements. In animals, uncrossed projections DN ipsilateral RN thalamus may explain this phenomenon. aim of study was clarify anatomy connections in humans. METHODS authors applied advanced deterministic fiber tractography a template 488 subjects Human Connectome...

10.3171/2015.4.jns142741 article EN Journal of neurosurgery 2015-10-09

Favorable imaging profile according to the Alberta Stroke Program Early CT Score (ASPECTS) on non-contrast head is a key criterion for selection of patients with ischemic stroke from large vessel occlusion (LVO) IA revascularization therapies.To analyze factors associated changes in ASPECTS during inter-hospital transfer and determine how deterioration affects eligibility endovascular procedures.We analyzed their potential impact therapies anterior circulation strokes. Clinical demographic...

10.1136/neurintsurg-2016-012331 article EN Journal of NeuroInterventional Surgery 2016-04-22

BACKGROUND: Trigeminal neuralgia is a relatively common neurosurgical pathology with multiple management options. Microvascular decompression (MVD) nonablative and considered the gold standard. However, stereotaxic radiosurgery (SRS) percutaneous rhizotomy (PSR) are 2 noninvasive but ablative options that have rapidly gained support. OBJECTIVE: To use Medicare claims data in conjunction literature review to assess usage, effectiveness, cost-effectiveness of 3 different invasive treatments...

10.1227/neu.0000000000000430 article EN Neurosurgery 2014-05-28

The utilization of telemedicine in healthcare has increased dramatically during the recent COVID-19 pandemic. This study aimed to investigate feasibility perform remote patient monitoring after full endoscopic spine surgery via a smartphone application that also allows communication with patients.

10.3171/2023.2.spine23136 article EN Journal of Neurosurgery Spine 2023-04-14

Background Endovascular treatment of wake-up strokes (WUS) has been previously described, mostly with the use pharmacological thrombolysis or first generation thrombectomy devices. Objective To describe outcomes WUS treated modern endovascular therapy since Food and Drug Administration approval stent retrievers, to identify predictors good clinical outcome in this population stroke patients. Methods We performed a multicenter retrospective analysis consecutive patients who underwent...

10.1136/neurintsurg-2014-011586 article EN Journal of NeuroInterventional Surgery 2015-01-29

Interlaminar endoscopic spine surgery has been introduced and utilized for lumbar lateral recess decompression. We modified this technique it bilateral stenoses without significant central stenosis. Here we present the surgical details clinical outcome of ligamentum flavum sparing unilateral laminotomy decompression (ULBRD).Prospectively collected registry full-endoscopic surgeries was reviewed retrospectively. One hundred eighty-two consecutive cases from a single center between September...

10.14245/ns.2244344.172 article EN cc-by-nc Neurospine 2022-12-26

<b>Background</b> Aneurysms arising from basilar perforator arteries are very rare. A primary goal of surgery is always preservation flow. However, in most surgically managed cases the literature, sacrifice was reported. It important for literature to demonstrate that patency an achievable goal. <b>Objective</b> To present second reported case flow surgical management artery aneurysms. <b>Clinical Presentation</b> 45-year-old woman presented with World Federation Neurologic Surgeons grade 1...

10.1055/s-0033-1356488 article EN Journal of Neurological Surgery Part A Central European Neurosurgery 2014-08-11

OBJECTIVE Spina bifida represents one of the most common birth defects, occurring in approximately 1–2 children per 1000 live births worldwide. The functional level patients with spina is highly variable and believed to be correlated anatomical lesion. clinical picture well established, but correlation intraoperative neuromonitoring (IONM) data has not been investigated. Furthermore, potential for preserving function beyond apparent also objective this research was determine presence...

10.3171/2023.11.peds23424 article EN Journal of Neurosurgery Pediatrics 2024-02-01

Traumatic spinal cord injury (tSCI) causes an immediate loss of neurological function, and the prediction recovery is difficult in acute phase. In this study, we used contrast-enhanced ultrasound imaging to quantify intraspinal vascular disruption acutely after tSCI. a rodent thoracic tSCI model, revealed perfusion area deficit that was positively correlated with severity negatively hindlimb locomotor function at 8 weeks injury. The index calculated by normalizing contrast inflow center...

10.1126/scitranslmed.adn4970 article EN Science Translational Medicine 2024-09-18

Objectives To present and validate a chicken wing model for endoscopic endonasal microsurgical skill development. Setting A surgical environment was constructed using Styrofoam box measurements from radiological studies. Endoscopic visualization instrumentation were utilized in manner to mimic operative setting. Design Five participants instructed complete four sequential tasks: (1) opening the skin, (2) exposing main artery its neurovascular sheath, (3) (4) separating nerve artery. Time...

10.1055/s-0033-1348026 article EN Journal of Neurological Surgery Part B Skull Base 2013-07-12

The anatomy of the carotid artery has traditionally been understood into segments that correspond to surrounding relevant anatomy. Transcranial surgery favors seven classification initially posited by our group in 1996. With advent endoscopic approaches a new term added lexicon "the paraclival internal (ICA)." This "paraclival" is very familiar segment for all endoscopically trained skull base surgeons but clear correlate transcranial not described. purpose study improve communication...

10.1055/s-0035-1568870 article EN Journal of Neurological Surgery Part B Skull Base 2015-11-30

OBJECTIVE Anterior cervical discectomy and fusion (ACDF) is the most common treatment for degenerative disease of spine. Given high rate pseudarthrosis in multilevel stand-alone ACDF, there a need to explore utility novel grafting materials. In this study, authors present single-institution retrospective study patients with spine who underwent ACDF surgery or without cellular allograft supplementation. METHODS prospectively collected database, 28 supplemented (ViviGen) 25 decellularized...

10.3171/2021.3.focus2150 article EN Neurosurgical FOCUS 2021-06-01

Retrochiasmatic, retroinfundibular craniopharyngiomas are surgically challenging tumors. Anterolateral, posterolateral, and endoscopic endonasal approaches represent the most commonly used techniques to access these tumors, but all require an extensive exposure time, each has its own risks limitations. The subtemporal approach is a well-known neurosurgical that rarely described for craniopharyngiomas.To assess feasibility, advantages, disadvantages of craniopharyngiomas.Five patients with...

10.1227/neu.0000000000000972 article EN Operative Neurosurgery 2015-08-19

Abstract Traumatic spinal cord injury (tSCI) leads to an immediate loss of neurological function, with its recovery being difficult predict in the acute phase. Here, we developed a contrast-enhanced ultrasound (CEUS) imaging biomarker quantify intraspinal vascular disruption after tSCI. In rodent thoracic tSCI, CEUS revealed perfusion area deficit (PAD) which increased severity (p = 0.001). The PAD size significantly correlated hindlimb locomotor function at 8 weeks post (R 2 0.82, p &lt;...

10.1101/2024.01.04.24300837 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2024-01-04

<h3>Background</h3> Favorable imaging profile according to the Alberta Stroke Program Early CT Score (ASPECTS) on noncontrast head is a key criterion for selection of patients with ischemic stroke from large vessel occlusion (LVO) intra-arterial (IA) revascularization therapies. <h3>Objective</h3> The goal our study was analyze factors associated changes in ASPECTS during inter-hospital transfer and determine their impact eligibility endovascular procedures. <h3>Methods</h3> We analyzed...

10.1136/neurintsurg-2016-012589.51 article EN cc-by-nc 2016-07-01

All brain surgery requires some degree of iatrogenic trauma to healthy tissue. Minimally invasive approaches tumors offer the potential decreasing this compared with conventional approaches. However, there are no validated radiologic models examine axonal damage after minimally entry into brain. To present a cadaveric model cannulation using fractional anisotropy measurements obtained from diffusion tensor magnetic resonance imaging (MRI). Two different methods access compared. Freshly...

10.1055/s-0037-1606543 article EN Journal of Neurological Surgery Part A Central European Neurosurgery 2017-10-17
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