Waldo R. Guerrero
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Vascular Malformations Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebral Venous Sinus Thrombosis
- Peripheral Artery Disease Management
- Neurological Disorders and Treatments
- Atrial Fibrillation Management and Outcomes
- Neurological Disease Mechanisms and Treatments
- Cardiovascular Health and Disease Prevention
- Cerebrospinal fluid and hydrocephalus
- Moyamoya disease diagnosis and treatment
- Optical Imaging and Spectroscopy Techniques
- Antiplatelet Therapy and Cardiovascular Diseases
- Clinical practice guidelines implementation
- Neurosurgical Procedures and Complications
- Photoacoustic and Ultrasonic Imaging
- Neurological disorders and treatments
- Mesenchymal stem cell research
- Cardiovascular and Diving-Related Complications
- Blood Coagulation and Thrombosis Mechanisms
University of South Florida
2006-2025
Ponce Health Sciences University
2025
University of Iowa Hospitals and Clinics
2017-2024
Tampa General Hospital
2016-2024
Waldorf College
2013-2024
Florida College
2010-2024
TESLA (Czechia)
2024
Universidad Científica del Sur
2024
Cooper University Hospital
2013-2023
Stroke Association
2021-2023
Patients with ischemic stroke attributed to large- or small-vessel disease are not considered at high risk for atrial fibrillation (AF), and the AF incidence rate in this population is unknown.To determine whether long-term cardiac monitoring more effective than usual care detection patients through 12 months of follow-up.The STROKE-AF trial was a randomized (1:1), multicenter (33 sites US) clinical that enrolled 496 between April 2016 July 2019, primary end point follow-up August 2020....
Approximately 10% to 20% of large vessel occlusion (LVO) strokes involve tandem lesions (TLs), defined as concomitant intracranial LVO and stenosis or the cervical internal carotid artery. Mechanical thrombectomy (MT) may benefit patients with TLs; however, optimal management procedural strategy lesion remain unclear.
Importance Recent large infarct thrombectomy trials used heterogeneous imaging modalities and time windows for patient selection. Noncontrast computed tomographic (CT) scan is the most common stroke approach. It remains uncertain whether effective patients with infarcts identified using noncontrast CT alone within 24 hours of onset. Objective To evaluate effect in a on Design, Setting, Participants Open-label, blinded–end point, bayesian-adaptive randomized trial interim analyses early...
Sigma receptors are putative targets for neuroprotection following ischemia; however, little is known on their mechanism of action. One the key components in demise neurons ischemic injury disruption intracellular calcium homeostasis. Fluorometric imaging was used to examine effects sigma receptor activation changes concentrations ([Ca(2+)](i)) evoked by vitro ischemia cultured cortical from embryonic rats. The agonist, 1,3-di-o-tolyl-guanidine (DTG), shown depress [Ca(2+)](i) elevations...
Limited data are available about the outcomes of mechanical thrombectomy (MT) for real-world patients with stroke presenting a large core infarct.To investigate safety and effectiveness MT vessel occlusion an Alberta Stroke Program Early Computed Tomography Score (ASPECTS) 2 to 5.This retrospective cohort study used from Thrombectomy Aneurysm Registry (STAR), which combines prospectively maintained databases 28 thrombectomy-capable centers in US, Europe, Asia. The included 2345 internal...
Favorable imaging profile according to the Alberta Stroke Program Early CT Score (ASPECTS) on non-contrast head is a key criterion for selection of patients with ischemic stroke from large vessel occlusion (LVO) IA revascularization therapies.To analyze factors associated changes in ASPECTS during inter-hospital transfer and determine how deterioration affects eligibility endovascular procedures.We analyzed their potential impact therapies anterior circulation strokes. Clinical demographic...
The overall risk of ischemic stroke from a chronically occluded internal carotid artery (COICA) is around 5%-7% per year despite receiving the best available medical therapy. Here, authors propose radiographic classification COICA that can be used as guide to determine technical success and safety endovascular recanalization for symptomatic assess changes in systemic blood pressure following successful revascularization.
The association between the street drug spice (K-2 or herbal incense), a synthetic marijuana, and intracranial hemorrhage (ICH) has not yet been described, but it with acute ischemic stroke (AIS),1 seizure, myocardial infarction.2 Two young patients (31 25 years old) independently presented to our hospital subarachnoid (SAH) after inhalation. first also had 2 large intraparenchymal hemorrhages (IPH); other AIS. Both were previously healthy without hypertension, coagulopathy, bleeding...
We aimed to describe the safety and efficacy of mechanical thrombectomy (MT) with or without intravenous thrombolysis (IVT) for patients tandem lesions whether using intraprocedural antiplatelet therapy influences MT's IVT treatment.
The STROKE AF study found that in patients with prior ischemic stroke attributed to large-artery atherosclerotic disease (LAD) or small-vessel occlusive (SVD), 12% developed over 1 year when monitored an insertable cardiac monitor (ICM). occurrence subsequent years is unknown.
Background Endovascular therapy (EVT) stands as an established and effective intervention for acute ischemic stroke in patients harboring tandem lesions (TLs). However, the optimal anesthetic strategy EVT TL remains unclear. This study aims to evaluate impact of distinct techniques on outcomes presenting with TLs. Methods Patient-level data, encompassing cases from 16 diverse centers, were aggregated individuals anterior circulation TLs treated between January 2015 December 2020. A...
Background Flow diverters are the first-line treatment for specific intracranial aneurysms (iA). Surpass Evolve (SE) is a new-generation 64-wire flow diverter with high braid angle. Current literature on SE limited. We aimed to report first international real-world experience evaluating safety and effectiveness of SE. Methods The Safety Effectiveness Assessment (SEASE) was multicenter retrospective post-marketing cohort study including consecutive patients treated iAs between 2020 2022....
BACKGROUND The use of the Surpass Evolve flow diverter for intracranial aneurysms (IAs) has shown promising results, but there are no studies that evaluated its effectiveness remnant previously treated IAs. This study aimed to evaluate safety and METHODS subanalysis is derived from SEASE (Safety Effectiveness Assessment Evolve) registry, a retrospective, multicentric, international cohort conducted across 15 academic institutions in North America Europe between July 2020 October 2022. Adult...
BACKGROUND Recent randomized clinical trials of endovascular therapy in patients with large infarct provided new evidence support interventions acute ischemic stroke. The Society Vascular and Interventional Neurology Guidelines Practice Standards committee aims to provide up‐to‐date recommendations on focused relevant questions. Here, we review current for the selection treatment anterior circulation vessel occlusion infarct. METHODS assembled a writing group recruited interdisciplinary...
Objective: The present study explored the association between losses incurred due to breast cancer diagnosis, symptoms of depression, PANIC/GRIEF, and contextual factors within context Hispanic/Latina (H/L) patients diagnosed with (BC). Methods: This was a cross-sectional adult H/L BC (n = 129). participants were women (stages 0–4) in past five years. Sociodemographic variables assessed, as well depression (Patient Health Questionnaire-9; Spanish version), grief (The Affective Neuroscience...
Stenting and flow diversion for aneurysmal sub arachnoid hemorrhage (aSAH) require the use of dual antiplatelet therapy (DAPT).To investigate whether DAPT is associated with hemorrhagic complication following placement external ventricular drains (EVD) in patients aSAH.Rates radiographically identified EVD were compared between who received stenting or diversion, underwent microsurgical clipping coiling did not receive by way a backward stepwise multivariate analysis.Four hundred forty-three...
Complex wide-neck intracranial aneurysms are challenging to treat. We report a multicenter experience using the LVIS Jr stent for "Y-stent"-assisted coiling embolization of bifurcation aneurysms.Seven centers provided retrospective data on patients who underwent Y-stenting. Technical complications, immediate posttreatment angiographic results, clinical outcomes, and imaging follow-up were assessed.Thirty patients/aneurysms treated: 15 basilar tip, 8 middle cerebral artery, 4 anterior...
Background In response to the COVID-19 pandemic, many centers altered stroke triage protocols for protection of their providers. However, effect workflow changes on patients receiving mechanical thrombectomy (MT) has not been systematically studied. Methods A prospective international study was launched at initiation pandemic. All included participated in Stroke Thrombectomy and Aneurysm Registry (STAR) Endovascular Neurosurgery Research Group (ENRG). Data collected during peak months surge...
It is unknown when to start anticoagulation after acute ischemic stroke (AIS) from atrial fibrillation (AF). Early may prevent recurrent infarctions but provoke hemorrhagic transformation as AF strokes are typically larger and transformation-prone. Later increases risk of secondary in this time frame. Our aim was compare early with apixaban patients or transient attack (TIA) versus warfarin administration at later intervals.AREST (Apixaban for Prevention Recurrent Embolic Stroke Hemorrhagic...