A5031762120- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Peripheral Artery Disease Management
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological Disease Mechanisms and Treatments
- Meningioma and schwannoma management
- Moyamoya disease diagnosis and treatment
- Cerebral Venous Sinus Thrombosis
- Spinal Hematomas and Complications
- Neurosurgical Procedures and Complications
- Aortic aneurysm repair treatments
- Neurofibromatosis and Schwannoma Cases
- Vascular Procedures and Complications
- Cardiovascular and Diving-Related Complications
- Cerebrospinal fluid and hydrocephalus
- Cardiovascular Health and Disease Prevention
- Clinical practice guidelines implementation
- Spinal Fractures and Fixation Techniques
- Management of metastatic bone disease
- Neurological disorders and treatments
University of Iowa Hospitals and Clinics
2021-2025
Hospital of the University of Pennsylvania
2023-2024
University of Pennsylvania Health System
2023-2024
University of Iowa
2022-2024
Swedish Medical Center
2022-2024
Universidad Científica del Sur
2024
University of Pennsylvania
2023
Montefiore Medical Center
2022
Neurological Surgery
2022
Universidad San Francisco de Quito
2020
Approximately 10% to 20% of large vessel occlusion (LVO) strokes involve tandem lesions (TLs), defined as concomitant intracranial LVO and stenosis or the cervical internal carotid artery. Mechanical thrombectomy (MT) may benefit patients with TLs; however, optimal management procedural strategy lesion remain unclear.
There is limited evidence on the indication and role of mechanical thrombectomy (MT) in patients with distal medium-vessel occlusions (DMVOs). The aim this systematic review meta-analysis was to evaluate all available efficacy safety MT techniques (stent retriever, aspiration) primary secondary DMVOs.Five databases were searched from inception January 2023 for studies DMVOs. Outcomes interest included favorable functional outcome (90-day modified Rankin scale (mRS) 0-2), successful...
Background The available evidence supporting the use of endovascular thrombectomy (EVT) in acute ischemic stroke patients with large core has increased recent release Thrombectomy for Emergent Salvage Large Anterior Circulation Ischemic Stroke (TESLA), Efficacy and Safety In Extended Lesion Time Window (TENSION), Therapy Evaluation (LASTE) trials, providing critical information on additional subgroups not included initial trials. We aimed to study efficacy safety EVT stratify by several...
Endovascular treatment (EVT) is part of the usual care for proximal vessel occlusion strokes. However, safety and effectiveness EVT distal medium occlusions remain unclear. We sought to compare clinical outcomes medical management (MM) isolated occlusions.
We aimed to describe the safety and efficacy of mechanical thrombectomy (MT) with or without intravenous thrombolysis (IVT) for patients tandem lesions whether using intraprocedural antiplatelet therapy influences MT's IVT treatment.
Background Endovascular therapy (EVT) stands as an established and effective intervention for acute ischemic stroke in patients harboring tandem lesions (TLs). However, the optimal anesthetic strategy EVT TL remains unclear. This study aims to evaluate impact of distinct techniques on outcomes presenting with TLs. Methods Patient-level data, encompassing cases from 16 diverse centers, were aggregated individuals anterior circulation TLs treated between January 2015 December 2020. A...
Background Flow diverters are the first-line treatment for specific intracranial aneurysms (iA). Surpass Evolve (SE) is a new-generation 64-wire flow diverter with high braid angle. Current literature on SE limited. We aimed to report first international real-world experience evaluating safety and effectiveness of SE. Methods The Safety Effectiveness Assessment (SEASE) was multicenter retrospective post-marketing cohort study including consecutive patients treated iAs between 2020 2022....
Abstract Vaginal infection is a gynecological problem in women of reproductive age with multiple health outcomes. The most common forms include bacterial vaginosis (BV), vulvovaginal candidiasis (VC), and aerobic vaginitis (AV). Our main goals were to evaluate different types vaginal infections Ecuadorian large urban area (Quito) characterize the microbiota colonization by opportunistic species. We collected swabs epidemiological surveys from 414 June 2016 July 2017. analyzed samples for...
BACKGROUND The use of the Surpass Evolve flow diverter for intracranial aneurysms (IAs) has shown promising results, but there are no studies that evaluated its effectiveness remnant previously treated IAs. This study aimed to evaluate safety and METHODS subanalysis is derived from SEASE (Safety Effectiveness Assessment Evolve) registry, a retrospective, multicentric, international cohort conducted across 15 academic institutions in North America Europe between July 2020 October 2022. Adult...
Distal embolization after endovascular thrombectomy (EVT) is common. We aimed to determine factors associated with tissue infarction in the territories of distal emboli.This a retrospective cohort study consecutive patients anterior circulation large vessel occlusions who underwent EVT from 2015 2021. Patients Thrombolysis In Cerebral Infarction (TICI) 2b reperfusion and follow-up imaging were identified. Baseline characteristics, procedural details, findings reviewed. Primary outcome was...
Background When mechanical thrombectomy (MT) fails to achieve successful reperfusion, rescue stenting (RS) has proven be a feasible therapy. However, the available evidence remains underpowered assess clinical outcomes. We aimed compare safety and efficacy of RS versus routine medical management in patients with failed MT using an aggregated meta‐analysis. Methods A systematic review was performed from inception July 2022 all studies after MT. Outcomes interest included modified Rankin scale...
Background The potentially higher risk of hemorrhagic complications is concern in stent-assisted coiling (SAC) ruptured wide-necked intracranial aneurysms (IAs). Woven EndoBridge (WEB) considered an appealing alternative since antiplatelet therapy not required. Herein, we aimed to compare the safety and effectiveness WEB vs. SAC for treatment IAs. Methods This was international cross-sectional study consecutive patients treated wide-neck IAs with or at four high-volume neurovascular centers...
Importance Stroke-to-recanalization time is a strong predictor of outcomes in anterior circulation large-vessel occlusion (LVO). The authors aimed to evaluate functional early (<6 h) vs. late (6–24 windows for thrombectomy-treated basilar artery occlusions. Methods Patients were derived from the Posterior Circulation Ischemic Stroke Evaluation: Analyzing Radiographic and Intra-procedural Predictors Mechanical Thrombectomy (PC-SEARCH) Registry retrospectively analyzed thrombectomy...
Recent randomized controlled trials demonstrated superiority of mechanical thrombectomy compared to medical therapy in acute basilar artery occlusions, however, little data is available guide clinicians functional prognosis and risk stratification.