- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Peripheral Artery Disease Management
- Stroke Rehabilitation and Recovery
- Neurological Disease Mechanisms and Treatments
- Medical Imaging and Analysis
- Vascular Malformations Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Neuroinflammation and Neurodegeneration Mechanisms
- Moyamoya disease diagnosis and treatment
- Long-Term Effects of COVID-19
- Neurological Disorders and Treatments
- Neurosurgical Procedures and Complications
- Cerebrospinal fluid and hydrocephalus
- COVID-19 and healthcare impacts
- Intracerebral and Subarachnoid Hemorrhage Research
- Vascular Procedures and Complications
- Atherosclerosis and Cardiovascular Diseases
- Vascular Anomalies and Treatments
- Intraoperative Neuromonitoring and Anesthetic Effects
- Meningioma and schwannoma management
- Inflammatory Biomarkers in Disease Prognosis
University of Iowa Hospitals and Clinics
2019-2025
University of Iowa
2020-2024
Neurology, Inc
2020-2021
Carver Bible College
2020
Hospital Base Guillermo Almenara Irigoyen
2017-2020
Approximately 10% to 20% of large vessel occlusion (LVO) strokes involve tandem lesions (TLs), defined as concomitant intracranial LVO and stenosis or the cervical internal carotid artery. Mechanical thrombectomy (MT) may benefit patients with TLs; however, optimal management procedural strategy lesion remain unclear.
Successful reperfusion is one of the strongest predictors functional outcomes after mechanical thrombectomy (MT). Despite continuous advancements in MT technology and techniques, failure still occurs ≈15% to 30% patients with large vessel occlusion strokes undergoing MT. We aim evaluate safety efficacy rescue intracranial stenting for stroke failed MT.The SAINT (Stenting Angioplasty Neurothrombectomy) Study a retrospective analysis prospectively collected data from 14 comprehensive centers...
Background A better understanding of real‐world practice patterns in the endovascular treatment for large vessel occlusion acute ischemic stroke is needed. Here, we report methods and initial results Society Vascular Interventional Neurology (SVIN) Registry. Methods The SVIN Registry an ongoing prospective, multicenter, observational registry capturing patients with undergoing since November 2018. Participating sites also contributed pre‐SVIN data collected per institutional prospective...
There is limited evidence on the indication and role of mechanical thrombectomy (MT) in patients with distal medium-vessel occlusions (DMVOs). The aim this systematic review meta-analysis was to evaluate all available efficacy safety MT techniques (stent retriever, aspiration) primary secondary DMVOs.Five databases were searched from inception January 2023 for studies DMVOs. Outcomes interest included favorable functional outcome (90-day modified Rankin scale (mRS) 0-2), successful...
Elevated blood pressure after endovascular thrombectomy (EVT) has been associated with an increased risk of hemorrhagic transformation and poor functional outcomes. However, the optimal hemodynamic management EVT remains unknown, course in acute phase ischemic stroke not well characterized. This study aimed to identify patient subgroups distinct trajectories their association radiographic
Backgrounds Recent trials have shown improved outcomes after mechanical thrombectomy (MT) for vertebrobasilar occlusion (VBO) stroke. However, there is a paucity of data regarding safety and rescue intracranial stenting (RS) failed MT (FRRS+) posterior circulation We sought to compare RS reperfusion without (FRRS−). Methods This retrospective analysis the Stenting Angioplasty in NeuroThrombectomy (SAINT) study, multicenter collaboration involving prospectively collected databases. Patients...
Background Previous studies have shown that when thrombectomy has failed, rescue intracranial stenting is associated with better clinical outcomes compared failed reperfusion. However, comparative data regarding stent type are lacking. Objective To compare the procedural and of balloon-mounted stents (BMS) those self-expandable (SES). Methods Retrospective analysis a prospectively collected database from Stenting Angioplasty in NeuroThrombectomy (SAINT) consortium. Patients were included if...
Distal embolization after endovascular thrombectomy (EVT) is common. We aimed to determine factors associated with tissue infarction in the territories of distal emboli.This a retrospective cohort study consecutive patients anterior circulation large vessel occlusions who underwent EVT from 2015 2021. Patients Thrombolysis In Cerebral Infarction (TICI) 2b reperfusion and follow-up imaging were identified. Baseline characteristics, procedural details, findings reviewed. Primary outcome was...
Background When mechanical thrombectomy (MT) fails to achieve successful reperfusion, rescue stenting (RS) has proven be a feasible therapy. However, the available evidence remains underpowered assess clinical outcomes. We aimed compare safety and efficacy of RS versus routine medical management in patients with failed MT using an aggregated meta‐analysis. Methods A systematic review was performed from inception July 2022 all studies after MT. Outcomes interest included modified Rankin scale...
Randomized clinical trials have failed to prove that the safety and efficacy of endovascular treatment for symptomatic intracranial atherosclerotic disease (ICAD) is better than medical management. A recent study using a self-expandable stent showed acceptable lower rates periprocedural complications.To balloon-mounted (BMS) in ICAD.Prospectively maintained databases from 15 neuroendovascular centers between 2010 2020 were reviewed. Patients included if they had severe stenosis target...
Background The hyperdense middle cerebral artery sign on computed tomography indicates proximal occlusion. Recent reports suggest an association between the and successful reperfusion. prognostic value of in patients receiving mechanical thrombectomy has not been extensively studied. Aims Our study aims to evaluate functional outcome with M1 occlusions that had undergone thrombectomy. Methods We conducted a single-center retrospective observational cohort 102 consecutive presenting acute...
The availability of cone-beam CT perfusion (CBCTP) in angiography suites may improve large-vessel occlusion (LVO) triage and reduce reperfusion times for patients presenting during extended time window. We aim to evaluate the maps correlation agreement between multidetector (MDCTP) CBCTP when obtained sequentially undergoing endovascular therapy.
Background While mechanical thrombectomy (MT) is the standard of care for large vessel occlusion strokes, optimal management tandem occlusions (TO) remains uncertain. We aimed to determine current practice patterns among stroke physicians involved in treatment TO during MT. Methods distributed an online survey neurovascular practitioners (stroke neurologists, neurointerventionalists, neurosurgeons, and radiologists), members professional societies. After 2 months site was closed data were...
Background and Purpose: Mechanical thrombectomy (MT) is now the standard of care for large vessel occlusion (LVO) stroke. However, little known about frequency outcomes repeat MT (rMT) patients with recurrent LVO. Methods: This a retrospective multicenter cohort who underwent rMT at 6 tertiary institutions in United States between March 2016 2020. Procedural, imaging, outcome data were evaluated. Outcome discharge was evaluated using modified Rankin Scale. Results: Of 3059 treated during...
Flow diversion has established as standard treatment for intracranial aneurysms, the Surpass Streamline is only FDA-approved braided cobalt/chromium alloy implant with 72-96 wires. We aimed to determine safety and efficacy of in a post-marketing large United States cohort.
The optimal technique for treating tandem lesions (TLs) with endovascular therapy is debatable. authors evaluated the functional, safety, and procedural outcomes of different approaches in a multicenter study.
To compare the computed tomography perfusion (CTP) outcomes derived from two commercial CTP processing software and evaluate their concordance in terms of eligibility for mechanical thrombectomy (MT) acute ischemic stroke (AIS), based on DEFUSE III criteria.