A5041092012- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Peripheral Artery Disease Management
- Neurosurgical Procedures and Complications
- Vascular Malformations Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Cerebral Venous Sinus Thrombosis
- Spinal Fractures and Fixation Techniques
- Aortic aneurysm repair treatments
- Trauma and Emergency Care Studies
- Vascular Procedures and Complications
- Central Venous Catheters and Hemodialysis
- COVID-19 and healthcare impacts
- Neurological Disease Mechanisms and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Retinal and Optic Conditions
- Dysphagia Assessment and Management
- Coronary Interventions and Diagnostics
- COVID-19 Clinical Research Studies
- Cerebrospinal fluid and hydrocephalus
Icahn School of Medicine at Mount Sinai
2018-2025
Mount Sinai Hospital
2019-2025
Mount Sinai Health System
2020-2025
Mount Sinai Hospital
2023-2025
Yale University
2025
Cornell University
2025
Rehabilitation Institute of Kansas City
2025
University of Missouri
2025
Columbia University
2025
Neurology, Inc
2023
<h3>BACKGROUND AND PURPOSE:</h3> Coronavirus disease 2019 (COVID-19) is an active worldwide pandemic with diverse complications. Stroke as a presentation has not been strongly associated COVID-19. The authors aimed to retrospectively review link between COVID-19 and acute stroke. <h3>MATERIALS METHODS:</h3> We conducted retrospective case-control study of 41 cases 82 control subjects matched by age, sex, risk factors. Cases were patients who underwent stroke alert imaging confirmed on March...
The 2019 novel coronavirus outbreak and its associated disease (coronavirus [COVID-19]) have created a worldwide pandemic. Early data suggest higher rate of ischemic stroke in severe COVID-19 infection. We evaluated whether relationship exists between emergent large vessel occlusion (ELVO) the ongoing outbreak.
Coronavirus disease 2019 (COVID-19) has been associated with an increased incidence of thrombotic events, including stroke. However, characteristics and outcomes COVID-19 patients stroke are not well known.We conducted a retrospective observational study risk factors, characteristics, short-term in large health system New York City. We included consecutively admitted acute cerebrovascular events from March 1, 2020 through April 30, 2020. Data were stratified by status, demographic variables,...
Background A better understanding of real‐world practice patterns in the endovascular treatment for large vessel occlusion acute ischemic stroke is needed. Here, we report methods and initial results Society Vascular Interventional Neurology (SVIN) Registry. Methods The SVIN Registry an ongoing prospective, multicenter, observational registry capturing patients with undergoing since November 2018. Participating sites also contributed pre‐SVIN data collected per institutional prospective...
Artificial intelligence (AI) software is increasingly applied in stroke diagnostics. However, the actual performance of AI tools for identifying large vessel occlusion (LVO) real time a real-world setting has not been fully studied.To determine accuracy real-world, three-tiered multihospital network.All consecutive head and neck CT angiography (CTA) scans performed during codes run through an engine (Viz LVO) between May 2019 October 2020 were prospectively collected. CTA readings by...
<h3>ABSTRACT</h3> <h3>BACKGROUND AND PURPOSE:</h3> Robustness against input data perturbations is essential for deploying deep-learning models in clinical practice. Adversarial attacks involve subtle, voxel-level manipulations of scans to increase models' prediction errors. Testing model performance on examples adversarial images provides a measure robustness, and including the training set can improve model's robustness. In this study, we examined modifications robustness predicting...
Importance Randomized clinical trials have shown the efficacy of endovascular therapy (EVT) for acute large vessel occlusion strokes. The benefit EVT in stroke with distal, medium (DMVO) remains unclear. Objective To examine and safety outcomes associated patients primary DMVO when compared a control cohort treated medical management (MM) alone. Design, Setting, Participants This multicenter, retrospective study pooled data from who had an anterior circulation emergency DMVO, defined as any...
Aneurysmal subarachnoid hemorrhage is associated with high rate of morbidity and mortality. We aimed to assess prognostic impact sex, race, ethnicity in these patients.Nationwide Inpatient Sample (2000-2019) was used identify patients presenting aneurysmal as primary diagnosis. Patient age, race/ethnicity, insurance status, socioeconomic comorbidities, type the hospital, treatment modality for aneurysm repair were extracted. The previously validated Nationwide Subarachnoid Hemorrhage...
Objective We aimed to evaluate the association between rescue therapy (RT) and functional outcomes compared medical management (MM) in patients presenting after failed mechanical thrombectomy (MT). Methods This cross‐sectional study utilized prospectively collected maintained data from Society of Vascular Interventional Neurology Registry, spanning 2011 2021. The cohort comprised with large vessel occlusions (LVOs) MT. primary outcome was shift degree disability, as gauged by modified Rankin...
<h3>BACKGROUND AND PURPOSE:</h3> Atherosclerotic plaque composition and structure contribute to the risk of rupture embolization. Virtual histology by intravascular ultrasonography high-resolution MR imaging are new modalities that have been used characterize morphology in peripheral arteries. <h3>MATERIALS METHODS:</h3> The objectives this study were 1) determine correlation between virtual histology–intravascular histopathologic analysis (reference standard) 2) explore comparative results...
Background Previous studies have shown that when thrombectomy has failed, rescue intracranial stenting is associated with better clinical outcomes compared failed reperfusion. However, comparative data regarding stent type are lacking. Objective To compare the procedural and of balloon-mounted stents (BMS) those self-expandable (SES). Methods Retrospective analysis a prospectively collected database from Stenting Angioplasty in NeuroThrombectomy (SAINT) consortium. Patients were included if...
Introduction: Patients with aSAH that are critically ill often undergo interhospital transfer (IHT) for multiple reasons including emergent treatment, physician second opinion, and patient preference. 1,2 Clinical radiographic predictors of early death transition to comfort care may help guide IHT decisions. 3 In this retrospective study, we seek deterioration in patients undergoing IHT. We hypothesized higher grade would be at a risk the peri-interhospital phase. Additionally, more likely...
This study examined the strength and stability of motor signals in low gamma high bands vascular electrocorticograms (VECoG) recorded with endovascular stent-electrode arrays (Stentrodes) implanted superior sagittal sinus two participants severe paralysis due to Amyotrophic Lateral Sclerosis. 
Methods: VECoG were from COMMAND trial, an Early Feasibility Study Stentrode brain-computer interface (BCI) (NCT05035823). The performed attempted movements their ankles or hands. band-pass...
INTRODUCTION: Implantable Brain-computer interfaces (BCIs) aim to provide people with paralysis a means control devices using decoded brain signals. Predominantly, implantable BCIs have required craniotomy place penetrating or surface electrodes on the brain. Here, we present results of an early feasibility study (EFS) Synchron BCI, fully implanted system delivered minimally invasive endovascular technique. METHODS: The COMMAND EFS, multi-center, prospective, single-arm, open label clinical...
INTRODUCTION: Pediatric arteriovenous malformations (AVM) are rare lesions with significant morbidity and mortality. Presentations may vary widely between the neonatal period, infantile older age groups. Literature characterizing incidence of these complex lesions, their symptoms, overall prognosis in setting modern improved endovascular techniques understanding pathophysiology is limited. METHODS: Data from 2006-2019 HCUP KID database identified 1,224 AVM patients less than one year using...
An octogenarian patient with a medical history of hypertension and prior stroke (baseline modified Rankin Scale score 1) presented acute onset left-sided hemiplegia neglect was found to have right middle cerebral artery M1 occlusion, likely from an embolic clot as there no hint intracranial atherosclerosis or dissection in the CT scan. He underwent emergent EVT using direct aspiration technique via novel super large-bore 0.092-inch ID catheter, which positioned segment. This is first...
Background Approximately one in three patients with acute ischemic stroke (AIS) suffer from a premorbid disability prior to their incident AIS. These have largely been excluded clinical trials of endovascular thrombectomy (EVT) for the treatment AIS and current literature remains unclear regarding safety efficacy EVT these patients. Methods We queried our prospectively maintained registry December 1, 2014 October 31, 2023 identify all who underwent EVT. Patients were stratified by baseline...
Purpose Large bore catheters are increasingly used in mechanical thrombectomy (MT) for large vessel occlusions (LVOs). Objective To evaluate the efficacy and safety of super-large Cereglide 0.092" (C-92) catheter, featuring largest inner diameter available. Methods A multicenter observational study was conducted across 12 comprehensive stroke centers United States. Efficacy outcomes included first pass effect (FPE) successful reperfusion. FPE defined as a MT achieving modified Treatment...