A5046846719- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury Research
- Neurosurgical Procedures and Complications
- Cerebrospinal fluid and hydrocephalus
- Venous Thromboembolism Diagnosis and Management
- Psychosomatic Disorders and Their Treatments
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Arrest and Resuscitation
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Cerebral Venous Sinus Thrombosis
- Epilepsy research and treatment
- Cloud Computing and Resource Management
- Long-Term Effects of COVID-19
- Cardiac, Anesthesia and Surgical Outcomes
- Migraine and Headache Studies
- Intensive Care Unit Cognitive Disorders
- Functional Brain Connectivity Studies
- Ultrasound in Clinical Applications
- Hemodynamic Monitoring and Therapy
- Advanced Data Storage Technologies
- Peripheral Artery Disease Management
- Vascular Malformations Diagnosis and Treatment
Icahn School of Medicine at Mount Sinai
2016-2025
Mount Sinai Health System
2020-2024
Presbyterian Hospital
2024
New York Hospital Queens
2024
Columbia University
2024
NewYork–Presbyterian Hospital
2024
Mount Sinai Hospital
2019-2023
King's College London
2023
Moss Rehabilitation Hospital
2023
Mount Sinai Hospital
2016-2022
Endovascular recanalization treatment for acute ischemic stroke is a complex, time-sensitive intervention. Trip-and-treat an interhospital service delivery model that has not previously been evaluated in the literature and consists of shared mobile interventional team travels to primary centers provide on-site capability. We compared times between trip-and-treat traditional drip-and-ship model.We performed retrospective analysis on 86 consecutive eligible patients with secondary large vessel...
Coronavirus disease 2019 (COVID-19) has been associated with an increased incidence of thrombotic events, including stroke. However, characteristics and outcomes COVID-19 patients stroke are not well known.We conducted a retrospective observational study risk factors, characteristics, short-term in large health system New York City. We included consecutively admitted acute cerebrovascular events from March 1, 2020 through April 30, 2020. Data were stratified by status, demographic variables,...
<h3>BACKGROUND AND PURPOSE:</h3> Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infection is associated with hypercoagulability. We sought to evaluate the demographic and clinical characteristics of cerebral venous thrombosis among patients hospitalized for disease 2019 (COVID-19) at 6 tertiary care centers in New York City metropolitan area. <h3>MATERIALS METHODS:</h3> conducted a retrospective multicenter cohort study 13,500 consecutive COVID-19 who were between March 1 May...
We present a retrospective analysis of patients who underwent minimally invasive endoscopic intracerebral hemorrhage (ICH) evacuation to identify variables that were associated with long-term outcome.Minimally ICH was performed on supratentorial fit prespecified clinical inclusion and exclusion criteria. Demographic, clinical, radiographic factors previously demonstrated impact functional outcome in included univariate favorable (modified Rankin Scale score, 0-3) at 6 months. Factors the...
Abstract Background The worldwide burden of stroke remains high, with increasing time-to-treatment correlated worse outcomes. Yet subtype determination, most importantly between stroke/non-stroke and ischemic/hemorrhagic stroke, is not confirmed until hospital CT diagnosis, resulting in suboptimal prehospital triage delayed treatment. In this study, we survey portable, non-invasive diagnostic technologies that could streamline by making initial determination type, thereby reducing...
Background The recently completed Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH) trial demonstrated a benefit for endoport-mediated evacuation within ≤24 hours lobar hemorrhages but not basal ganglia (BGH). We performed an exploratory evaluation the Stereotactic Cerebral Underwater Blood Aspiration (SCUBA) technique BGH evacuation. Methods reviewed data from patients presenting to urban health system with who underwent SCUBA according institutional guidelines. Three...
Background and Purpose: Triage of patients with emergent large vessel occlusion stroke to primary centers followed by transfer comprehensive leads increased time endovascular therapy. A Mobile Interventional Stroke Team (MIST) provides an alternative model transferring a MIST Thrombectomy Capable Center (TSC) perform Our aim is determine whether the more time-efficient improved clinical outcomes compared standard drip-and-ship (DS) mothership models. Methods: This prospective observational...
Intracerebral hemorrhage (ICH) is a devastating form of stroke with no proven treatment. However, minimally invasive endoscopic evacuation promising potential therapeutic option for ICH. Herein, the authors examine factors associated long-term functional independence (modified Rankin Scale [mRS] score ≤ 2) in patients spontaneous ICH who underwent evacuation.Patients supratentorial had presented to large urban healthcare system from December 2015 October 2018 were triaged central hospital...
Background Minimally invasive evacuation may help ameliorate outcomes after intracerebral hemorrhage (ICH). However, hospital length of stay (LOS) post-evacuation is often long and costly. Objective To examine factors associated with LOS in a large cohort patients who underwent minimally endoscopic evacuation. Methods Patients presenting to health system spontaneous supratentorial ICH qualified for if they met the following inclusion criteria: age ≥18, premorbid modified Rankin Scale (mRS)...
Background and Purpose: Young patients with malignant cerebral edema have been shown to benefit from early decompressive hemicraniectomy. The impact of concomitant infection coronavirus disease 2019 (COVID-19) how this should weigh in on the decision for surgery is unclear. Methods: We retrospectively reviewed all COVID-19–positive admitted neuroscience intensive care unit monitoring. Patients >50% middle artery involvement computed tomography imaging were considered at risk edema....
We present Nitro, a high-performance in-memory key-value storage engine used in Couchbase 4.5 Global Secondary Indexes. The Nitro is well suited for the recent hardware trends like large amounts of memory and many CPU cores. leverages latch-free data structures tries to achieve linear scalability index read-write operations. offers concurrent readers writers, lightweight database snapshots, stable scan, backup recovery integrated into Indexes (GSI) observed significant improvement...
Objective Refractory status epilepticus (RSE) treated with anesthetic agents can be associated complications including respiratory depression and hypotension. Ketamine is an emerging RSE treatment, but optimal dosing timing are unknown. We studied provider attitudes practices regarding the use of ketamine for RSE. Methods A literature review informed creation survey, developed by professionals in epilepsy, pharmacy, neurocritical care. The survey was distributed to members Critical Care EEG...
Access to endovascular therapy (ET) in cases of acute ischemic stroke may be limited, and rapid transfer eligible patients hospitals with capability is needed.To determine the optimal timing diagnostic CT angiography confirm large vessel occlusion (LVO).Of 57 emergency department transfers Mount Sinai Hospital (MSH) for possible ET from January 2015 through March 2016, 39 (68%) underwent ET, among whom 22 (56%) had before 17 (44%) on arrival. We compared mean outside hospital arrival groin...
Concern for reactive meningeal enhancement after lumbar puncture (LP) is a common reason performing brain MRI prior to LP. We sought determine actual incidence of unexplained LP.We collected results from all contrasted MRIs in patients admitted adult neurology at New York City hospital over 3-year period. used electronic medical records whether an LP had been done within 30 days MRI. The control group comprised those not preceded by imaging. Number cases was compared between groups using...
Background Studies on stroke risk following cardiac procedures addressed only perioperative and long‐term limited higher‐risk procedures, were poorly generalizable, often failed to stratify by type. We calculated in the intermediate period compared with common noncardiac surgeries medical admissions. Methods Results The Nationwide Readmissions Database contains readmission data for 49% of US admissions 2013. age‐adjusted rates up 90 days postdischarge. used Cox regression calculate hazard...
Impulse control disorders (ICDs) are nonmotor complications of dopaminergic medications characterized by problems in behavioral self-control. Common management involves discontinuing or lowering medication, often producing motor worsening. We performed a retrospective chart review Parkinson's disease (PD) patients treated with clozapine for ICDs. Four ICD were identified. Three men. All 4 took at the time that ICDs developed; all received dopamine agonist therapy. included compulsive...