A5001101162- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebral Venous Sinus Thrombosis
- Stroke Rehabilitation and Recovery
- Vascular Procedures and Complications
- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Spinal Fractures and Fixation Techniques
- Neurosurgical Procedures and Complications
- Spine and Intervertebral Disc Pathology
- Moyamoya disease diagnosis and treatment
- Meningioma and schwannoma management
- Intracerebral and Subarachnoid Hemorrhage Research
- Coronary Interventions and Diagnostics
- Orthopedic Surgery and Rehabilitation
- Peripheral Artery Disease Management
- Neurological Complications and Syndromes
- Spinal Hematomas and Complications
- Vascular Malformations and Hemangiomas
- Neurological Disorders and Treatments
- Vascular Anomalies and Treatments
- Epilepsy research and treatment
Munson Medical Center
2020-2024
Wayne State University
2010-2023
Beijing Luhe Hospital Affiliated to Capital Medical University
2019-2023
Shandong Provincial Hospital
2023
Great Lakes Environmental Center
2023
Kaleida Health
2019-2021
University at Buffalo, State University of New York
2019-2021
Gates (United States)
2020-2021
Capital Medical University
2021
Jacobs (United States)
2020-2021
OBJECTIVE Acute tandem occlusions of the cervical internal carotid artery and an intracranial large vessel present treatment challenges. Controversy exists regarding which lesion should be addressed first. The authors sought to evaluate endovascular approach for revascularization these lesions at Gates Vascular Institute. METHODS performed a retrospective review prospectively maintained, single-institution database. They analyzed demographic, procedural, radiological, clinical outcome data...
The purpose of this study was to compare the efficacy repetitive transcranial magnetic stimulation (rTMS) applied at different frequencies contra-lesional hemisphere optimize treatment post-stroke non-fluent aphasia.Patients with aphasia were divided randomly into four groups: a high-frequency rTMS (HF-rTMS) group (10 Hz), low-frequency (LF-rTMS) (1 sham group, and control group. All groups received standard (consisting drug therapy, conventional physical exercises, speech training); in...
Objective: Very early mobilization was thought to contribute beneficial outcomes in stroke-unit care, but the optimal intervention strategy including initiation time and intensity of are unclear. In this study, we sought confirm rehabilitative effects different times (24 vs. 48 h) with intensities (routine or intensive) ischemic stroke patients within 3 groups. Materials Methods: We conducted a randomized controlled trial blinded follow-up assessment. Patients stroke, first recurrent,...
Importance Randomized clinical trials have shown the efficacy of endovascular therapy (EVT) for acute large vessel occlusion strokes. The benefit EVT in stroke with distal, medium (DMVO) remains unclear. Objective To examine and safety outcomes associated patients primary DMVO when compared a control cohort treated medical management (MM) alone. Design, Setting, Participants This multicenter, retrospective study pooled data from who had an anterior circulation emergency DMVO, defined as any...
Animal models continue to improve our understanding of tinnitus pathogenesis and aid in development new treatments. However, there are no diagnostic biomarkers for tinnitus-related pathophysiology use awake, freely moving animals. To address this disparity, two complementary methods were combined examine reliable (rats repeatedly administered salicylate or exposed a single noise event): inhibition acoustic startle manganese-enhanced MRI. Salicylate-induced resulted wide spread supernormal...
Background Middle meningeal artery (MMA) embolization is an emerging therapy for the resolution of subacute or chronic subdural hematoma (CSDH). CSDH patients are often elderly and have several comorbidities. We evaluated our experience with transradial access (TRA) MMA using predominantly Onyx under conscious sedation. Methods Data consecutive who underwent during a 2-year period (2018–2019) were analyzed from single-center, prospectively-maintained database. Patient demographics,...
Although revascularization rates after endovascular thrombectomy for large vessel acute ischemic stroke (AIS) are high (71%), only 46% of patients achieve functional independence at 90 days. The present study was designed to explore a new method predicting the prognosis AIS recanalization. A total 200 anterior circulation who received therapy were enrolled. Logistic regression analysis clinical characteristics on performed. predictive power sub-items in National Institute Health scale...
Adjuvant neuroprotective therapies for acute ischemic stroke (AIS) have demonstrated benefit in animal studies, albeit without human translation. We investigated the safety and efficacy of high-flow normobaric oxygen (NBO) after endovascular recanalization anterior circulation stroke. This is a prospective randomized controlled study. Eligible patients were to receive NBO by Venturi mask (FiO
The perception of a steep learning curve associated with transradial access has resulted in its limited adoption neurointervention despite the demonstrated benefits, including decreased access-site complications.To compare curves versus transfemoral diagnostic cerebral angiograms obtained by five neurovascular fellows as primary operator.The first 100-150 consecutive and angiographic scans performed each fellow between July 2017 March 2020 were identified. Mean fluoroscopy time per artery...
Lymphocytic hypophysitis is an uncommon autoimmune condition that often results in significant morbidity. Although most cases resolve spontaneously or after a short course of steroids, rarely, refractory can cause persistent neurological deficits despite aggressive medical and surgical management. A 41-year-old woman presented with progressive visual loss the left eye was found to have sellar mass. She underwent transsphenoidal surgery because lesion enlargement. Histopathology consistent...
This 52-year-old man with no remarkable medical history, anticoagulation use, and history of trauma was noted to have a subacute–chronic left subdural hematoma during outpatient headache evaluation. No occult vascular lesion or cross-calvarial supply the right middle meningeal artery (MMA) side identified on bilateral selective external carotid injections. Because patient preferred non-surgical management, we performed MMA embolization Onyx 18 (Medtronic), utilizing Headway Duo microcatheter...
Acute ischemic stroke due to basilar artery occlusion (BAO) carries a very poor prognosis. Functional outcomes in BAO patients undergoing endovascular therapy (EVT) may differ according the specific pathological mechanisms. We aimed explore impact of underlying mechanisms on prognosis at 90-days and long-term follow-up treated with EVT. analyzed consecutive EVT from December 2012 2018 single center (Xuanwu Hospital). Patients were classified into either an intracranial atherosclerotic...
Among cerebral venous thrombosis (CVT) patients, those with infarction have more severe clinical presentations and worse outcomes.Identifying biomarkers associated in CVT may help understand the pathogenesis provide potentially useful therapeutic markers.Fifty-two patients were prospectively recruited divided into three groups: acute/subacute (ASVI, n=30), without (ASOVI, n=13), chronic (n=9).Blood brain barrier (BBB) permeabilityrelated proteins, including claudin-5, occludin, matrix...
Objective This study assesses whether stress-induced hyperglycemia is a predictor of poor outcome at 3 months for patients with acute ischemic stroke (AIS) treated by endovascular treatment (EVT) and impacted their previous blood glucose status. Methods retrospective collected data from 576 AIS due to large vessel occlusion (LVO) EVT March 2019 June 2022. The sample was composed 230 346 without diabetes mellitus (DM), respectively, based on premorbid diabetic Prognosis assessed modified...
Transradial access for neurointerventions offers advantages of fewer access-site complications, reduced procedure time, and greater patient comfort over transfemoral access. Data about transradial flow diversion are limited. We share our early experience with in a relatively large case series.Consecutive patients who underwent Pipeline embolization device (Medtronic) deployment via were included the study, irrespective location laterality intracranial aneurysm. The cases performed between...
Background For the treatment of intracranial aneurysms, low-profile visualized intraluminal support (LVIS) stent is a new generation highly visible-braided that was recently introduced in China. Here, we report our single-center retrospective experience safety and efficacy utilizing LVIS for stent-assisted coiling aneurysms.Methods We included 218 patients with aneurysms consecutively treated SR stents at center this study. Postoperative follow-up embolization scores, procedural...
Venous stenting has been proven to be a safe and effective therapeutic option for patients with idiopathic intracranial hypertension (IIH) cerebral venous sinus stenosis (CVSS). However, its use in thrombosis-related CVSS less reported.To explore the safety efficacy of thrombosis (CVST)-related CVSS.The clinical presentation, treatment, outcome CVST-related received chronic stage after failed medical treatment were retrospectively evaluated.A total 17 included. Mean pressure gradient across...