A5065182991- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Systemic Lupus Erythematosus Research
- Venous Thromboembolism Diagnosis and Management
- Neurosurgical Procedures and Complications
- T-cell and B-cell Immunology
- Peripheral Artery Disease Management
- Immune Cell Function and Interaction
- Vascular Malformations Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Lipid Membrane Structure and Behavior
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Meningioma and schwannoma management
- Ion Channels and Receptors
- Voice and Speech Disorders
- Advanced Biosensing Techniques and Applications
- Older Adults Driving Studies
- Neuroscience and Neuropharmacology Research
- Poetry Analysis and Criticism
- Inflammatory Myopathies and Dermatomyositis
- Atherosclerosis and Cardiovascular Diseases
- Mindfulness and Compassion Interventions
University of Pennsylvania
2022-2024
Philadelphia VA Medical Center
2022-2024
University at Buffalo, State University of New York
2018-2023
Canon (United States)
2021
Kaleida Health
2019-2021
Jacobs (United States)
2021
Jacobs Institute
2020
Gates (United States)
2019-2020
Buffalo State University
2018-2019
KSE (United States)
2015
Background Middle meningeal artery (MMA) embolization is an emerging therapy for the resolution of subacute or chronic subdural hematoma (CSDH). CSDH patients are often elderly and have several comorbidities. We evaluated our experience with transradial access (TRA) MMA using predominantly Onyx under conscious sedation. Methods Data consecutive who underwent during a 2-year period (2018–2019) were analyzed from single-center, prospectively-maintained database. Patient demographics,...
The vanilloid receptor TRPV1 is an exquisite nociceptive sensor of noxious heat, but its temperature-sensing mechanism yet to define. Thermodynamics dictate that this channel must undergo unusually energetic allosteric transition. Thus, it fundamental importance measure directly the energetics transition in order properly decipher mechanism. Previously, using submillisecond temperature jumps and patch-clamp recording, we estimated heat activation for opening incurs enthalpy change on 100...
Objective The pathogenesis of cutaneous lupus erythematosus (CLE) is multifactorial, and CLE difficult to treat due the heterogeneity inflammatory processes among patients. Antimalarials such as hydroxychloroquine (HCQ) quinacrine (QC) have long been used first‐line systemic therapy; however, many patients do not respond treatment with antimalarials require immunosuppressants that produce undesirable side effects. Given complexity unpredictability responses antimalarial treatments in...
Background Patients with cerebral aneurysms treated the Pipeline embolization device (PED) are maintained on dual antiplatelet therapy (DAPT) to prevent thromboembolic complications. Rates of minor, “nuisance” bleeding in these patients remain unknown. We sought evaluate frequency and factors associated this its effect DAPT compliance. Methods performed a multicenter retrospective cohort study consecutive cases intracranial PED. Patient characteristics, aneurysm complications were analyzed....
The purpose of this cross-sectional study was to determine the percentage US population with 60 min ground or air access accredited state-designated endovascular-capable stroke centers (ECCs) and non-endovascular capable (NECCs) NECCs an ECC within a 30 drive.Stroke were identified classified broadly as ECCs NECCs. Geographic mapping performed. divided into census blocks, their centroids calculated. Fastest travel times from centroid nearest NECC estimated.Overall, 49.6% residents had ECCs....
Background There are no reports that describe complete flow control using concurrent transient rapid ventricular pacing or intravenous (IV) adenosine and afferent arterial balloon arrest to aid transvenous embolization of cerebral arteriovenous malformations (AVM). We our experience with the use this technique in patients undergoing AVM embolization. Methods Consecutive whom was attempted at institute between January 2017 July 2019 were included. Anatomical features, number stages, arrest,...
The value of clot imaging in patients with emergent large vessel occlusion (ELVO) treated thrombectomy is unknown.We performed retrospective analysis (clot density, perviousness, length, diameter, distance to the internal carotid artery (ICA) terminus and angle interaction (AOI) between aspiration catheter) consecutive cases middle cerebral (MCA) its association first pass effect (FPE, TICI 2c-3 after a attempt).Patients (n = 90 total) FPE had shorter length (9.9 ± 4.5 mm vs. 11.7 4.6 mm, P...
A Pipeline embolization device (PED; Medtronic, Dublin, Ireland) can be deployed using either a biaxial or triaxial catheter delivery system.To compare the use of these two systems for intracranial aneurysm treatment with PED.A retrospective study patients undergoing PED deployment between 2014 and 2016 was conducted. Experienced neurointerventionalists performed procedures. Patients who received multiple PEDs adjunctive coils were excluded. The groups compared time, total fluoroscopy...
<h3>Introduction</h3> Middle meningeal artery (MMA) embolization for the treatment of subacute/chronic subdural hematoma (cSDH) is an emerging therapy minimally invasive blood products. Trans radial access (TRA) may offer certain benefits to this patient population who are often on thinners with multiple comorbid medical issues. <h3>Methods</h3> 46 consecutive patients between 2018 and January 2020 undergoing trans MMA Onyx were analyzed from a single center prospectively maintained...