- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Meningioma and schwannoma management
- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Neurological Disorders and Treatments
- Spinal Hematomas and Complications
- Augmented Reality Applications
- Spine and Intervertebral Disc Pathology
- Healthcare Operations and Scheduling Optimization
- Musculoskeletal pain and rehabilitation
- Aortic Disease and Treatment Approaches
- Glaucoma and retinal disorders
- Neurological Disease Mechanisms and Treatments
- Moyamoya disease diagnosis and treatment
- Ethics in medical practice
- Medical Imaging and Analysis
- Surgical Sutures and Adhesives
West Virginia University
2015-2025
Blanchette Rockefeller Neurosciences Institute
2020-2025
Centre Hospitalier Universitaire de Reims
2024
Swedish Medical Center
2024
Jackson Memorial Hospital
2024
Rhode Island Hospital
2024
Swedish Medical Center
2024
Stony Brook Medicine
2024
Université de Reims Champagne-Ardenne
2024
Santa Barbara Cottage Hospital
2024
Data on large vessel strokes are important for resource allocation and infrastructure development.To determine an annual incidence of occlusions (LVOs) a thrombectomy eligible patient population.All patients with acute ischemic stroke discharged over 3 years from tertiary-level hospital serving geographic area were evaluated LVO (M1, internal carotid artery terminus, basilar artery). The was determined the hospital's 4-county primary service (PSA, population 210 000) based each county's...
BackgroundPatients receiving standard treatment for chronic subdural hematoma have a high risk of failure. The effect adjunctive middle meningeal artery embolization on the failure in this population remains unknown.MethodsWe randomly assigned patients with symptomatic to undergo as an adjunct (embolization group) or receive alone (control group). Either surgical nonsurgical had been chosen each patient before randomization. primary efficacy outcome was composite following events: recurrent...
Limited efficacy of IV recombinant tissue plasminogen activator (rt-PA) for large vessel occlusions (LVO) raises doubts about its utility prior to endovascular therapy.To compare outcomes and hospital costs anterior circulation LVOs (middle cerebral artery, internal carotid artery terminus (ICA-T)) treated with either primary therapy alone (EV-Only) or bridging (IV+EV)).A single-center retrospective analysis was performed. Clinical demographic data were collected prospectively relevant cost...
M2 occlusions may result in poor outcomes and potentially benefit from endovascular therapy. Data on the rate of strokes is lacking.Patients with acute ischemic stroke discharged over a period 3 years tertiary level hospital 'stroke belt' were evaluated for baseline vascular imaging. Regional national incidence was calculated discharge multicounty data.There 2739 ICD-9 based AIS discharges. 116 (4%, 95% CI 3.5% to 5%) patients constituted second most common occlusion site. The median...
Delays in delivering endovascular stroke therapy adversely affect outcomes. Time-sensitive treatments such as interventions benefit from methodically developed protocols. Clearly defined roles these protocols allow for parallel processing of tasks, resulting consistent delivery care.To present the outcomes a quality-improvement (QI) process directed at reducing treatment times tertiary level academic medical center.A Six-Sigma-based QI was over 3-month period. After an initial analysis,...
Background The Woven EndoBridge (WEB) device is approved in the USA for treatment of unruptured wide-neck bifurcation aneurysms. However, safety and effectiveness WEB ruptured intracranial aneurysms not clear. We aim to evaluate perioperative patients with Methods This retrospective study, conducted at eight centers USA, included treated setting subarachnoid hemorrhage (SAH). Safety outcomes intraoperative complications such as vessel perforation, thromboembolic events, postoperative...
Middle meningeal artery embolization (MMAE) is emerging as a promising adjunctive treatment in patients with chronic subdural hematomas (cSDH). This study presents real world multicenter data comparing outcomes cSDH undergoing surgical alone or combined MMAE. multi-institutional, multinational, retrospective, propensity-matched utilized the TriNetX platform to compare evacuation and MMAE versus surgery for cSDH. The included inpatient readmission, need repeat surgery, mortality at 6 months...
Purpose Large bore catheters are increasingly used in mechanical thrombectomy (MT) for large vessel occlusions (LVOs). Objective To evaluate the efficacy and safety of super-large Cereglide 0.092" (C-92) catheter, featuring largest inner diameter available. Methods A multicenter observational study was conducted across 12 comprehensive stroke centers United States. Efficacy outcomes included first pass effect (FPE) successful reperfusion. FPE defined as a MT achieving modified Treatment...
Chiropractic cervical manipulation is a common practice utilized around the world.Most patients are never cleared medically for manipulation, which can be devastating those few who at increased risk dissections.The high velocity thrust used in produce significant strain on carotid and vertebral vessels.Once dissection has occurred, of thrombus formation, ischemic stroke, paralysis, even death drastically increased.In this case report, we highlight 32-year-old woman underwent chiropractic had...
OBJECTIVE The objective of this study was to investigate the neurovascular and anatomical differences in patients with lumbosacral transitional vertebrae (LSTV) associated risk injury minimally invasive spine surgery. METHODS authors performed a retrospective CT MR images lumbar obtained at their institution between 2010 2014. following characteristics were evaluated: level iliac crest relation L4-5 disc space, union veins arteries distribution inferior vena cava according different Moro...
Background Physician variablity in preoperative planning of endovascular implant deployment and associated inaccuracies have not been documented. This study aimed to quantify the variability accuracy physician flow diverter (FD) directly compares it with PreSize Neurovascular (Oxford Heartbeat Ltd) software simulations. Methods Eight experienced neurointerventionalists (NIs), blinded procedural details, were provided 3D rotational angiography (3D-RA) volumetric data along images annotated...
<h3>BACKGROUND AND PURPOSE:</h3> The impact of increased aneurysm packing density on angiographic outcomes has not been studied in a randomized trial. We sought to determine the potential for larger caliber coils achieve higher densities and improve results embolization intracranial aneurysms at 1 year. <h3>MATERIALS METHODS:</h3> Does Embolization with Larger Coils Lead Better Treatment Aneurysms (DELTA) was an investigator-initiated multicenter prospective, parallel, randomized, controlled...
<h3>BACKGROUND AND PURPOSE:</h3> Physician training and onsite proctoring are critical for safely introducing new biomedical devices, a process that has been disrupted by the pandemic. A teleproctoring concept using optical see-through head-mounted displays with proctor9s ability to see and, more important, virtually interact in operator9s visual field is presented. <h3>MATERIALS METHODS:</h3> Test conditions were created simulated bifurcation aneurysm flow model WEB device deployment. The...
Background Post-recanalization target vessel re-occlusion (TVR) following endovascular thrombectomy (EVT) is a known complication of the procedure, and it associated with worse long-term functional outcomes. The incidence factors that contribute to TVR are not well understood, particularly within immediate timeframe EVT. Methods A prospective, multicenter study was performed across four comprehensive stroke centers on adult patients undergoing EVT for acute large occlusion. Modified...
Background The WEB device offers another option for treating wide neck bifurcation aneurysms (WNBA). objective was to compare procedure variables, radiation and implant cost between stent assisted coiling (SAC) WNBA. Methods A retrospective comparison of similarly sized WNBA treated with SAC or over 5-years performed. operating room (arrival-departure), anesthesia (intubation-extubation), duration (puncture-closure), fluoroscopy time dose(m-Gy) were recorded from the patients’ charts....
Graves' disease may be managed with thyroid embolization when other traditional strategies are less suitable. To date, no reports exist on the of ima artery for or outcomes this procedure. Here, we present a safe and successful report in neutropenic patient storm. A 30-year-old female history presented to community hospital heat intolerance, anxiousness, tachycardia, tachypnea. Further laboratory testing prompted diagnosis Embolization was chosen management because total thyroidectomy risked...
Artery of Percheron (AOP) is a rare anatomical variant, which supplies bilateral paramedian thalami and the rostral mesencephalon via single dominant thalamic perforating artery arising from P1 segment posterior cerebral artery. AOP infarcts can present with plethora neurological symptoms: altered mental status, memory impairment, hypersomnolence, coma, aphasia, vertical gaze palsy. Given lack classic stroke signs, majority are not diagnosed in emergency setting. Timely diagnosis an acute...
People older than 80 years of age constitute the most rapidly growing group in world. Several trials confirming superior efficacy endovascular therapy did not have an upper limit and showed favorable treatment effects, regardless age. Current American Heart Association/American Stroke Association guidelines do restrict based on as long other eligibility criteria are met. A 103-year-old woman presented 2 h after stroke onset secondary to a left internal carotid artery terminus (ICA-T)...
<h3>Background</h3> Endovascular therapy has been endorsed for emergent large vessel occlusions (ELVO). However the incidence of ELVO is ill defined and speculative. A methodical estimate these patients important developing systems care, resource allocation market projections. <h3>Objective</h3> To determine national burden by extrapolating rates from a tertiary rural health system that captures over 85% all ischemic strokes within its catchment area to inpatient sample (NIS) database....
A middle-aged patient presented with posterior circulation symptoms attributable to a large eccentric basilar trunk aneurysm. The planned treatment was flow diversion loose coil packing which successfully performed using Pipeline Flex device deployed from the left cerebral artery. complete procedure including live biplane fluoroscopy digitally recorded. had symptomatic improvement postoperatively and discharged on day 1. suffered cardiac arrest postoperative 3 secondary massive...