A5000869710- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Peripheral Artery Disease Management
- Spinal Cord Injury Research
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Vascular Procedures and Complications
- Spinal Hematomas and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Nerve Injury and Rehabilitation
- Moyamoya disease diagnosis and treatment
- Cerebral Venous Sinus Thrombosis
- Venous Thromboembolism Diagnosis and Management
- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Cerebrovascular and genetic disorders
- Cardiovascular Function and Risk Factors
- Muscle activation and electromyography studies
- Neuroscience and Neural Engineering
- Herpesvirus Infections and Treatments
- Musculoskeletal pain and rehabilitation
- Botulinum Toxin and Related Neurological Disorders
- Infectious Encephalopathies and Encephalitis
University of Pittsburgh
2022-2024
University of Pittsburgh Medical Center
2022
University of Iowa Hospitals and Clinics
2018-2021
University of Iowa
2018
Mayo Clinic
2017
WinnMed
2017
Background Knowledge regarding predictors of clinical and radiographic failures middle meningeal artery (MMA) embolization (MMAE) treatment for chronic subdural hematoma (CSDH) is limited. Purpose To identify MMAE failure CSDH. Materials Methods In this retrospective study, consecutive patients who underwent CSDH from February 2018 to April 2022 at 13 U.S. centers were included. Clinical was defined as reaccumulation and/or neurologic deterioration requiring rescue surgery. Radiographic a...
The choice of anesthesia type (general [GA] vs nongeneral [non-GA]) in middle meningeal artery embolization (MMAE) procedures for chronic subdural hematomas (cSDH) differs between institutions and left to care team discretion given lack standard guidelines. We compare the outcomes GA non-GA MMAE.
In this study, the neuroanatomy of swine lumbar spinal cord, particularly spatial orientation dorsal roots was correlated to anatomical landmarks spine and magnitude motor evoked potentials during epidural electrical stimulation (EES). We found that proximity stimulating electrode entry zone across segments a critical factor evoke higher peak-to-peak responses. Positioning close produced significantly impact on responses than rostro-caudal shift from segment segment. Based measurements...
Complex wide-neck intracranial aneurysms are challenging to treat. We report a multicenter experience using the LVIS Jr stent for "Y-stent"-assisted coiling embolization of bifurcation aneurysms.Seven centers provided retrospective data on patients who underwent Y-stenting. Technical complications, immediate posttreatment angiographic results, clinical outcomes, and imaging follow-up were assessed.Thirty patients/aneurysms treated: 15 basilar tip, 8 middle cerebral artery, 4 anterior...
By 2030, nonacute subdural hematomas (NASHs) will likely be the most common cranial neurosurgery pathology. Treatment with surgical evacuation may necessary, but recurrence rate after surgery is as high 30%. Minimally invasive middle meningeal artery embolization (MMAE) during perioperative period has been posited an adjunctive treatment to decrease potential for evacuation. We evaluated safety and efficacy of concurrent MMAE in a multi-institutional cohort.Data from 145 patients (median age...
Acute changes in motor performance due to levodopa were evaluated by a series of four tests unified their focus on wrist flexion–extension movements. Subjects with idiopathic Parkinson's disease this battery before (OFF) and after usual morning dose (ON). The test consisted (i) repetitive self-paced movement which velocity was be maximized; (ii) visually guided tracking sinusoid square wave; (Hi) an assay stretch reflex modulation during volitional sinusoidal tracking. maximal joint...
Laboratory/animal-based proof of principle study.To validate the accuracy a magnetic resonance imaging (MRI)-guided stereotactic system for intraspinal electrode targeting and demonstrate feasibility such controlling implantation electrodes.Intraspinal microstimulation (ISMS) is an emerging preclinical therapy, which has shown promise restoration motor function following spinal cord injury. However, inaccuracy associated with existing techniques remains major barrier preventing clinical...
An 88-year-old man presented with a 1-month history of altered mental status and seizures. His electrographic imaging findings were suggestive herpes simplex encephalitis (HSE), for which he was empirically treated acyclovir. He underwent two lumbar punctures 3 days apart; both cerebrospinal fluid analyses tested negative virus (HSV) by polymerase chain reaction (PCR). These results his continued deterioration after 9 acyclovir therapy prompted treatment steroids possible autoimmune...
Background A direct admission to angiosuite (DAA) strategy in transfer patients with large vessel occlusion (LVO) is considered decrease stroke time metrics and benefit functional outcomes. However, feasibility effectiveness of DAA have not been established rural settings. Fast door‐to‐reperfusion times high‐quality reperfusion are key predictors outcome LVO. To reduce treatment transferred suspected LVO, we initiated a triage protocol 2017. Methods We conducted nested interventional cohort...
Objective: To report a single-center experience using drug-eluting balloon mounted stents (DES) for endovascular treatment of atherosclerotic ostial vertebral artery stenosis (OVAS). Background: Posterior circulation is affected in up to 25% strokes, 20% them resulting from OVAS. The optimal management symptomatic OVAS remains controversial. DES have been introduced improve restenosis rates. Methods: We retrospectively analyzed prospectively collected data patients with dominant who...
Background Balloon test occlusion (BTO) with adjunctive single‐photon emission computed tomography has been used to predict tolerance after permanent internal carotid artery occlusion. Anatomic characteristics of the cerebral circulation might BTO outcomes and identify patients susceptible failure. Methods We performed a single‐center retrospective analysis who underwent from July 2013 June 2020. Patients passed clinical imaging; technetium‐99m‐ethyl cysteinate dimer was injected...
Background: Patients with an obstructive subclavian artery (SA) may exhibit symptoms of vertebrobasilar insufficiency known as steal syndrome (SSS). Endovascular treatment stent assisted percutaneous transluminal angioplasty (SAPTA) demonstrates significantly lower percentage intraoperative and postoperative complications in comparison open surgery. There is a 1-5% risk distal intracranial embolization through the ipsilateral vertebral (VA) during SAPTA. Objective: To assess safety...
Abstract Endovascular intervention has become the mainstay of treatment for subclavian artery stenosis in many centers, with high technical success and low complication rates. 1 , 2 However, potential embolization during proximal can lead to catastrophic posterior circulation ischemic complications.3–5 - 5 Although considered a rare complication, presence contralateral hypoplastic vertebral persisting anterograde blood flow on affected side is likely increase risk embolization. 3 The use...
Endovascular coiling has become the preferred treatment of many centers for management both ruptured and unruptured aneurysms. Coil migration is a rare complication that can lead to vessel occlusion in 90% cases. techniques coil retrieval have shown less rates than open surgery. Stent retriever devices been successfully used proximally migrated coils, however, distally coils still represent challenge with greater risk complications. In present technical video 1, we demonstrate successful M3...
Introduction Dural Sinus Malformation (DSM) is a rare and high risk mortality vascular pathology identified early postnatal due to common clinical symptoms like macrocephaly, downward wandering eyes, bulging pulsatile fontanels heart failure. Most DSMs resolves prenatally. It characterized by giant venous lake at the torcular region expanding towards infratentorial supratentorial spaces with usually existence of arteriovenous fistulas (dAVF). Pathophysiology are ballooning malformation...
Introduction The 2015 American Heart Association Guidelines recommended mechanical thrombectomy with stent‐retriever devices. A prior published analysis of national trends after one year in use and outcomes for stroke before publication the US guideline update showed improved functional lower peri‐procedural mortality. We analyze five years update. Methods analyzed National Inpatient Sample from 2012‐2019. ICD‐9 ICD‐10 codes identified Ischemic patients. Similar to previous study, discharge...
Introduction: Balloon test occlusion (BTO) with adjunctive single-photon emission computed tomography (SPECT) has been utilized to predict clinical tolerance after permanent internal carotid artery (ICA) occlusion. Cerebrovascular anatomical characteristics might BTO outcomes and identify patients susceptible failure. Methods: We performed a single center retrospective study of who underwent catheter based cerebral angiogram ICA from July 2013 June 2020. SPECT imaging was completed in all...