A5034332264- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Vascular Malformations Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebral Venous Sinus Thrombosis
- Meningioma and schwannoma management
- Moyamoya disease diagnosis and treatment
- Pancreatic function and diabetes
- Spinal Hematomas and Complications
- Glioma Diagnosis and Treatment
- Spinal Fractures and Fixation Techniques
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Cannabis and Cannabinoid Research
- Trigeminal Neuralgia and Treatments
- Spine and Intervertebral Disc Pathology
- Head and Neck Surgical Oncology
- Cerebrospinal fluid and hydrocephalus
- Medical Imaging and Analysis
- Advanced MRI Techniques and Applications
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
Neurological Surgery
2010-2024
NewYork–Presbyterian Hospital
2017-2024
Cornell University
2017-2024
Icahn School of Medicine at Mount Sinai
2024
New York Hospital Queens
2017-2024
North Shore University Hospital
2021-2024
Northwell Health
2021-2024
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2020-2024
TESLA (Czechia)
2024
Presbyterian Hospital
2017-2021
Chronic subdural hematoma (SDH) is a particularly challenging pathology due to high recurrence rates (2%-37%) and complex medical comorbidities that tend afflict the patient population. Recently, there have been several case series published describing use of middle meningeal artery (MMA) embolization as an alternative surgery for treatment new or recurrent chronic SDH.To describe our first 60 cases MMA SDH.MMA was performed using angiography, selective microcatheterization MMA, infusion...
Subacute and chronic subdural hematomas are common frequently recur after surgical evacuation. The effect of adjunctive middle meningeal artery embolization on the risk reoperation remains unclear. In a prospective, multicenter, interventional, adaptive-design trial, we randomly assigned patients with symptomatic subacute or hematoma an indication for evacuation to undergo plus surgery (treatment group) alone (control group). primary end point was recurrence progression that led repeat...
Importance Recent large infarct thrombectomy trials used heterogeneous imaging modalities and time windows for patient selection. Noncontrast computed tomographic (CT) scan is the most common stroke approach. It remains uncertain whether effective patients with infarcts identified using noncontrast CT alone within 24 hours of onset. Objective To evaluate effect in a on Design, Setting, Participants Open-label, blinded–end point, bayesian-adaptive randomized trial interim analyses early...
Purpose To develop microcapsules that immunoprotect pancreatic islet cells for treatment of type I diabetes and enable multimodal cellular imaging transplanted cells. Materials Methods All animal experiments were approved by the institutional care use committee. Gold nanoparticles functionalized with DTDTPA (dithiolated diethylenetriaminepentaacetic acid):gadolinium chelates (GG) coencapsulated using protamine sulfate as a clinical-grade alginate cross linker. Conventional...
Background and purpose Embolization of the middle meningeal artery (MMA) has recently been proposed as an alternative to surgery for treatment chronic subdural hematoma (SDH), several case reports have published supporting its efficacy. It suggested that primary pathologic process in SDH is repeated microhemorrhaging into collection from fragile neovasculature within membrane arises distal branches MMA. could thus provide a means eliminating this rebleeding. Materials methods Images were...
Background: Decompression of Chiari malformation is a common procedure in both pediatric and adult neurosurgery. Although the necessity for some bony removal universally accepted, other aspects surgery are subject debate. The most controversial points include optimal amount removal, use duraplasty (and type material), need subarachnoid dissection, tonsillar shrinkage. Material Methods: We critically reviewed literature to elucidate risks benefits different graft types clarify treatment...
OBJECTIVE Chronic subdural hematoma (cSDH) is a common and challenging pathology to treat due both the historically high recurrence rate following surgical evacuation medical comorbidities inherent in aging patient population that it primarily affects. Middle meningeal artery (MMA) embolization has shown promise treatment of cSDHs, most convincingly avoid relatively asymptomatic patients. Symptomatic patients requiring may also benefit from perioperative MMA prevent cSDH recurrence. The goal...
Abstract BACKGROUND Traditional treatment for symptomatic subdural hematoma (SDH) has been surgical evacuation, but recurrence rates are high and patients often harbor complex medical comorbidities. Growth is thought to be due the highly friable nature of vascularized membrane that forms after initial injury. There have reported cases middle meningeal artery (MMA) embolization recurrent SDH evacuation with goal eliminating arterial supply this membrane. OBJECTIVE To present first known case...
INTRODUCTION: Subdural hematoma (SDH) is quickly becoming the most common neurosurgical pathology due to aging population. Middle meningeal artery embolization (MMAE) has recently emerged as an effective adjunct surgical SDH evacuation by decreasing recurrence risk. MMAE also shown promise a standalone intervention, but clinical and radiographic predictors of successful remain ill-defined. METHODS: Retrospective review from 2020–2023 at high-volume center identified all cases performed...
INTRODUCTION: While well-established in Moyamoya Disease (MMD), the role of direct superficial temporal artery (STA) to middle cerebral (MCA) bypass non-Moyamoya (N-MMD) steno-occlusive syndromes remains controversial. Nonetheless, recurrent stroke risk N-MMD patients high despite best medical management. METHODS: Single-center retrospective review STA-MCA cases from 2014–2023 was performed. Cases were excluded if they involved double-barrel bypass, interposition grafts, or surgical...
Abstract BACKGROUND Thalamic glioblastomas (GBMs) represent a significant neurosurgical challenge. In view of the low incidence these tumors, outcome data and management strategies are not well defined. OBJECTIVE To identify natural history factors associated with survival in patients thalamic glioblastoma. METHODS A retrospective review all glioblastoma over 10-yr period was performed. Presenting clinical, radiological, were collected. Chi-squared Fisher's exact tests used to compare...
Abstract Understanding how individual cells behave inside living systems will help enable new diagnostic tools and cellular therapies. Superparamagnetic iron oxide particles can be used to label theranostic capsules for noninvasive tracking using MRI. Contrast changes from superparamagnetic are often subtle relative intrinsic sources of contrast, presenting a detection challenge. Here, we describe versatile postprocessing method, called Phase map cross‐correlation Detection Quantification...
In cases where mechanical thrombectomy (MT) fails, rescue stenting may be necessary to achieve reperfusion; however, the lack of standardized techniques or devices poses a challenge. This series aims present our early experience with Onyx Frontier™ and Resolute Onyx™ balloon-mounted drug-eluting stents for stenting.
<h3>Importance</h3> Elderly patients who undergo surgery for an isolated nontraumatic subdural hematoma (SDH) are at major risk SDH reaccumulation, which can cause further injury and disability. Few population-based studies have examined how often reaccumulates necessitates repeated operation. <h3>Objective</h3> To determine the rate of operation after evacuation SDH. <h3>Design, Setting, Participants</h3> In a cohort study, 2 parallel analyses were performed using data from National...
Introduction Current methods for angioplasty and stenting of the intracranial vasculature neurointervention are limited. The Wingspan Stent System is Food Drug Administration (FDA) approved with human device exemption a limited patient group despite numerous prospective registries trials demonstrating reasonable safety, still carries warnings from FDA its use. Given these limitations, we present technical nuances outcomes off-label use Resolute Onyx drug-eluting stent (DES)...
Online date: August 16, 2018 This article is published and distributed under the terms of Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)
Accurate sizing of the Woven EndoBridge (WEB) device is critical importance as it determines procedural safety and successful occlusion wide neck bifurcation aneurysms. The aim this study was to assess ability aneurysm volume assist in accurate WEB size selection.All patients with an intracranial treated SL or SLS between March 2019 October were identified for retrospective study. Aneurysm volumes calculated auto-segmentation using a three-dimensional rendering program on independent Syngo...
Hepatocyte transplantation is currently being considered as a new paradigm for treatment of fulminant liver failure. Xeno- and allotransplantation studies have shown considerable success, but the long-term survival immunorejection engrafted cells need to be further evaluated. Using novel alginate–protamine sulfate–alginate microcapsules, we coencapsulated luciferase-expressing HepG2 human hepatocytes with superparamagnetic iron oxide nanoparticles create magnetocapsules that are visible on...