Steven R. Messé
A5008639808- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Stroke Rehabilitation and Recovery
- Cardiovascular and Diving-Related Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Neurosurgical Procedures and Complications
- Antiplatelet Therapy and Cardiovascular Diseases
- Peripheral Artery Disease Management
- Cerebral Venous Sinus Thrombosis
- Cardiovascular Health and Disease Prevention
- Cardiac Arrhythmias and Treatments
- Optical Imaging and Spectroscopy Techniques
- Aortic aneurysm repair treatments
- Moyamoya disease diagnosis and treatment
- Trauma and Emergency Care Studies
- Congenital Heart Disease Studies
University of Pennsylvania
2016-2025
Hospital of the University of Pennsylvania
2016-2025
California University of Pennsylvania
2023-2024
Yale University
2013-2024
Arcadia
2024
Stroke Association
2021-2023
Medical University of South Carolina
2007-2022
Mercy Health
2022
University of Kansas
2022
SUNY Upstate Medical University
2014-2022
Purpose— The aim of this guideline is to present current and comprehensive recommendations for the diagnosis treatment acute spontaneous intracerebral hemorrhage. Methods— A formal literature search MEDLINE was performed. Data were synthesized with use evidence tables. Writing committee members met by teleconference discuss data-derived recommendations. American Heart Association Stroke Council’s Levels Evidence grading algorithm used grade each recommendation. Prerelease review draft...
Background and Purpose— To explore relationships among gender, body size, neck the diameters of common carotid artery (CCA) internal (ICA). Methods— Using multivariate regression, best predictors sonographic CCA ICA were determined based on age, height, weight, mass index, surface area, circumference, length, blood pressure. Results— Measurements obtained in 500 consecutive patients (age 52±15 years; 61% women). Mean (4.66±0.78 mm) (6.10±0.80 women significantly smaller than men: 5.11±0.87...
Background— Substantial efforts over the past decade have increased rates of intravenous tissue plasminogen activator (tPA) use in United States. We sought to determine changes patient characteristics and tPA time among hospitalized acute ischemic stroke (AIS) patients. Methods Results— analyzed all AIS patients (n=1 093 895) those arriving ≤2 hours treated with ≤3 after onset (n=50 798) from 2003 2011 American Heart Association’s Get Guideline–Stroke (GWTG–Stroke). Categorical data were by...
The incidence and impact of clinical stroke silent radiographic cerebral infarction complicating open surgical aortic valve replacement (AVR) are poorly characterized.We performed a prospective cohort study subjects ≥65 years age who were undergoing AVR for calcific stenosis. Subjects evaluated by neurologists preoperatively postoperatively underwent postoperative magnetic resonance imaging. Over 4-year period, 196 enrolled at 2 sites (mean age, 75.8±6.2 years; 36% women; 6% nonwhite)....
To determine patient and hospital characteristics associated with not providing IV tissue plasminogen activator (tPA) to eligible patients acute ischemic stroke (AIS) in clinical practice.We performed a retrospective cohort study of AIS arriving within 2 hours onset hospitals participating Get With The Guidelines-Stroke without documented contraindications tPA from April 2003 through December 2011, comparing those who received did not. Multivariable generalized estimating equation logistic...
Transcatheter aortic-valve replacement (TAVR) for the treatment of aortic stenosis can lead to embolization debris. Capture debris by devices that provide cerebral embolic protection (CEP) may reduce risk stroke.
Patients with ischemic stroke attributed to large- or small-vessel disease are not considered at high risk for atrial fibrillation (AF), and the AF incidence rate in this population is unknown.To determine whether long-term cardiac monitoring more effective than usual care detection patients through 12 months of follow-up.The STROKE-AF trial was a randomized (1:1), multicenter (33 sites US) clinical that enrolled 496 between April 2016 July 2019, primary end point follow-up August 2020....
To update the 2016 American Academy of Neurology (AAN) practice advisory for patients with stroke and patent foramen ovale (PFO).The guideline panel followed AAN 2017 development process to systematically review studies published through December formulate recommendations.In being considered PFO closure, clinicians should ensure that an appropriately thorough evaluation has been performed rule out alternative mechanisms (level B). In a higher risk mechanism identified, not routinely...
<h3>Importance</h3> Recent epidemiologic and therapeutic advances have transformed understanding of the role approach to patent foramen ovale (PFO) in ischemic stroke. Patent is likely responsible for approximately 5% all strokes 10% those occurring young middle-aged adults. <h3>Observations</h3> Randomized clinical trials demonstrated that, prevent recurrent stroke patients with PFO an otherwise-cryptogenic index stroke, closure superior antiplatelet medical therapy alone; these provided...
Patent foramen ovale (PFO) is a vestigial congenital cardiovascular structure present in around 25% of adults. In most cases, PFO entirely benign and requires no treatment. However, it may cause serious complications under certain circumstances.
Intracerebral hemorrhage (ICH) is the deadliest stroke subtype, and mortality rates are especially high in anticoagulation-associated ICH. Recently, specific anticoagulation reversal strategies have been developed, but it not clear whether there a time-dependent treatment effect for door-to-treatment (DTT) times clinical practice.
Limited data suggest that intracerebral hemorrhage related to oral anticoagulant therapy (OAT ICH) is associated with more expansion and a worse prognosis than spontaneous ICH (SICH).We examined patients enrolled in the placebo arm of CHANT study, prospective randomized trial putative neuroprotectant ICH. All had neuroimaging within 6 hours symptom onset at 72 hours. Initial volume were determined by central reader. Multivariable logistic regression was used determine factors mortality 90...
Objectives: 1) To evaluate the risk of subsequent stroke or death in patients with a cryptogenic and patent foramen ovale (PFO), atrial septal aneurysm (ASA), both. 2) establish optimal method prevention this population patients.
<b>Objective:</b> To examine whether antiplatelet medication use at onset of intracerebral hemorrhage (ICH) is associated with growth and outcome after spontaneous ICH using a large, prospectively collected database from recent clinical trial. <b>Methods:</b> The Cerebral Hemorrhage NXY-059 Treatment trial was randomized, placebo-controlled ICH. We analyzed patients in the placebo arm, correlated time initial volumes, first 72 hours, modified Rankin Score 90 days. Patients on oral...
Summary Background and objectives Cognitive impairment is common among persons with chronic kidney disease, but the extent to which nontraditional vascular risk factors mediate this association unclear. Design, setting, participants, & measurements We conducted cross-sectional analyses of baseline data collected from adults disease participating in Chronic Renal Insufficiency Cohort study. was defined as a Modified Mini-Mental State Exam score >1 SD below mean score. Results Among...