A5046089627- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Neurological Complications and Syndromes
- Traumatic Brain Injury and Neurovascular Disturbances
- Atrial Fibrillation Management and Outcomes
- Intracerebral and Subarachnoid Hemorrhage Research
- Stroke Rehabilitation and Recovery
- Pharmacological Effects and Toxicity Studies
- Moyamoya disease diagnosis and treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Restraint-Related Deaths
- Clinical practice guidelines implementation
- Oropharyngeal Anatomy and Pathologies
- Medical Coding and Health Information
- Cancer-related molecular mechanisms research
- Cardiovascular and Diving-Related Complications
- Neurological and metabolic disorders
- Retinal and Optic Conditions
- Botulinum Toxin and Related Neurological Disorders
- S100 Proteins and Annexins
- Cerebral Venous Sinus Thrombosis
- Blood Coagulation and Thrombosis Mechanisms
- Cardiovascular Health and Disease Prevention
William Harvey Hospital
2016-2023
East Kent Hospitals University NHS Foundation Trust
2016-2022
UNSW Sydney
2018
The University of Sydney
2015-2018
Westmead Hospital
2015-2018
George Institute for Global Health
2017-2018
Peking University
2017-2018
University of Pennsylvania
2018
National Cerebral and Cardiovascular Center
2018
Royal Prince Alfred Hospital
2017-2018
Introduction . Stroke remains a global leading cause of death and disability. Traditional description plasma biology in the aftermath acute ischaemic stroke favours development hypercoagulability, resulting from complex interplay between endothelial factors. However, no single assay measures overall coagulation process. We postulate that thrombin generation would assist identifying abnormalities after stroke. Aim To investigate using generation. Methods evaluated generation, measured with...
Introduction South Asian diaspora comprise one of the largest ethnic minority groups in world yet data about atrial fibrillation (AF) this demographic is understudied. Our aim to identify differences AF prevalence and treatment between Asians white British stroke patients. Method The UK arm a prospective ongoing large international repository on was analysed. Ethnic management those with ischemic were Results Of 3515 individuals recruited stroke, 1482 (men: 972, women: 510) 2033 (men:1141,...
A 76-year-old woman presented to hospital by ambulance 45 min after developing sudden onset left face and arm weakness. She was taking methotrexate prednisolone for rheumatoid arthritis. had been unwell with fever malaise 3 days. On examination, her temperature 39.1°C, pulse rate 90 per minute blood pressure 150/90 mm Hg. alert no signs of meningism. There a left-sided facial droop Chest abdomen examinations were normal. We assessed on treatment pathway suspected stroke view intravenous...
Abstract Background and purpose Studies on stroke in South Asian populations are sparse. The aim of this study was to compare differences age onset ischaemic patients living the United Kingdom India versus White British patients. Methods We studied UK Indian arms ongoing BRAINS study, an international prospective hospital‐based includes 4038 with first‐ever stroke, recruited from sites India. Results Of included patients, 1126 were Asians (ISA), while 1176 (BSA) 1736 (WB) residents. Patients...
A 47-year-old man with poorly controlled hypertension presented headaches, right-sided weakness and dysarthria. CT MRI scans of the brain showed widespread abnormalities including significant pontine oedema, basal ganglia corona radiata infarctions cerebellar white matter high signal. Imaging intracerebral vasculature also demonstrated wall irregularities. Initially a central nervous system inflammatory disorder was thought to be most likely diagnosis, possibly acute demyelinating...
Background: Diabetes mellitus and central obesity are more common among South Asian populations than White British people. This study explores the differences in diabetes Asians with stroke living United Kingdom, India, Qatar compared patients. Methods: The included UK, Indian, Qatari arms of ongoing large Bio-Repository DNA Stroke (BRAINS) international prospective hospital-based for stroke. BRAINS includes 4580 recruits from sites first-ever ischemic Results: population comprises 1751 (WB)...
To assess the relevance clinicians and radiologists assign to making hypertension (HTN) explicit in acutely symptomatic subjects admitted for either stroke, confusion or cognitive deficit, a revision was carried out of cases discussed our institution last eleven years, at Neuroradiology-Stroke Neuropsychiatry multidisciplinary meetings (MDTs). Consistency provided clinical information radiological findings concerning HTN were checked 11810 (Group 1), since both influence neuroimaging...