Adam Polifka
A5041533304- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Vascular Malformations Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Peripheral Artery Disease Management
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Neurosurgical Procedures and Complications
- Vascular Procedures and Complications
- Cervical and Thoracic Myelopathy
- Cardiac, Anesthesia and Surgical Outcomes
- Moyamoya disease diagnosis and treatment
- Meningioma and schwannoma management
- Central Venous Catheters and Hemodialysis
- Enhanced Recovery After Surgery
- Neurological Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Anesthesia and Pain Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Vascular Anomalies and Treatments
- Aortic Disease and Treatment Approaches
University of Florida
2017-2025
Neurological Surgery
2015-2024
Jacksonville College
2024
Mayo Clinic in Florida
2024
University of Washington
2023
Florida College
2017-2023
University of Tennessee Health Science Center
2023
University of Arkansas for Medical Sciences
2022
University of Florida Health
2017-2021
University of Louisville
2021
Background The elderly population (≥80 years) were underrepresented in recent trials of endovascular thrombectomy (EVT) for anterior circulation large vessel occlusion acute ischemic stroke (LVO-AIS) with low Alberta Stroke Program Early CT Score (ASPECTS) (≤5). Methods This study analyzed data from a prospectively maintained database 37 centers. primary cohort the comprised patients LVO-AIS aged ≥80 who underwent EVT ASPECTS≤5 2013 to 2023. outcome was favorable modified Rankin Scale (mRS)...
Background and Purpose— EG-1962 is a sustained release formulation of nimodipine administered via external ventricular drain in patients with aneurysmal subarachnoid hemorrhage. A randomized, open-label, phase 1/2a, dose-escalation study provided impetus for this to evaluate efficacy safety single intraventricular 600 mg dose hemorrhage, compared standard care oral nimodipine. Methods— Subjects were World Federation Neurological Surgeons grades 2–4, modified Fisher 2–4 had an inserted as...
Limited data are available about the outcomes of mechanical thrombectomy (MT) for real-world patients with stroke presenting a large core infarct.To investigate safety and effectiveness MT vessel occlusion an Alberta Stroke Program Early Computed Tomography Score (ASPECTS) 2 to 5.This retrospective cohort study used from Thrombectomy Aneurysm Registry (STAR), which combines prospectively maintained databases 28 thrombectomy-capable centers in US, Europe, Asia. The included 2345 internal...
Recent clinical trials have shown that mechanical thrombectomy is superior to medical management for large vessel occlusion up 24 hours from onset. Our objective examine the safety and efficacy of beyond standard care window.A retrospective review was undertaken multicenter Stroke Thrombectomy Aneurysm Registry (STAR). We identified patients who underwent hours. selected a matched control group in 6-24-hour window. used functional independence at 3 months as our primary outcome measure.We...
Aneurysmal subarachnoid hemorrhage (aSAH) predisposes to delayed neurological deficits, including stroke and cognitive neuropsychological abnormalities. Heparin is a pleiotropic drug that antagonizes many of the pathophysiological mechanisms implicated in secondary brain injury after aSAH.The authors performed retrospective analysis 86 consecutive patients with Fisher Grade 3 aSAH due rupture supratentorial aneurysm who presented within 36 hours were treated by surgical clipping 48 their...
Cervical kyphotic deformity can be a debilitating condition with symptoms ranging from mechanical neck pain, radiculopathy, and myelopathy to impaired swallowing horizontal gaze. Surgical correction of cervical kyphosis has the potential halt progression neurological clinical deterioration even restore function. There are various operative approaches techniques. Choosing optimal strategy is predicated on fundamental understanding spine biomechanics. Preoperative characterization...
Background Endovascular thrombectomy (EVT) is the standard-of-care for proximal large vessel occlusion (LVO) stroke. Data on technical and clinical outcomes in distal occlusions (DVOs) remain limited. Methods This was a retrospective study of patients undergoing EVT stroke at 32 international centers. Patients were divided into LVOs (internal carotid artery/M1/vertebrobasilar), medium (M2/A1/P1) isolated DVOs (M3/M4/A2/A3/P2/P3) categorized by technique. Primary outcome good functional...
Background Several studies have established the safety and efficacy of balloon guide catheters (BGCs) for large vessel occlusions. However, utility BGCs remains largely unexplored distal medium occlusions (DMVOs). In this study, we aim to compare outcomes BGC vs. Non-BGC in patients undergoing mechanical thrombectomy (MT) DMVO. Method This retrospective study from Stroke Thrombectomy Aneurysm Registry (STAR) encompassed adult with acute anterior cerebral artery, posterior middle...
Background Reducing intracranial hemorrhage (ICH) can improve patient outcome in acute ischemic stroke (AIS) intervention. We sought to identify ICH risk factors after AIS thrombectomy. Methods This is a retrospective review of the Stroke Thrombectomy and Aneurysm Registry (STAR) database. All patients who underwent thrombectomy with available data were included. Multivariable regression models developed predictors Subgroup analyses performed stratified by symptom status European Cooperative...
Background The role for the transradial approach mechanical thrombectomy is controversial. We sought to compare and transfemoral in a large multicenter database of acute ischemic stroke. Methods prospectively maintained Stroke Thrombectomy Aneurysm Registry (STAR) was reviewed patients who underwent an internal carotid artery (ICA) or middle cerebral M1 occlusion. Multivariate regression analyses were performed assess outcomes including reperfusion time, symptomatic intracerebral hemorrhage...
The object of this study was to assess outcomes in patients with arteriovenous malformations (AVMs) treated by Gamma Knife stereotactic radiosurgery (SRS); lesions were stratified size, symptomatology, and Spetzler-Martin (S-M) grade.The authors performed a retrospective analysis 102 for an AVM single-dose or staged-dose SRS between 1993 2004. Lesions grouped S-M grade, as hemorrhagic nonhemorrhagic, small (< 3 cm) large (≥ cm). Outcomes included death, morbidity (new neurological deficit,...
Flow diverters have emerged as a major tool in the treatment of cerebral aneurysms. A crucial issue with use flow is patency side branches covered by device, most importantly ophthalmic artery (OA).To assess OA after coverage pipeline embolization device (PED).All patients who had PED covering and whom angiographic follow-up was available were included study. The at systematically evaluated 2 authors not involved procedure.Of 95 treated patients, 1 81 (85%) PEDs 14 (15%). Mean 7.5 months,...
The Pipeline Embolization Device is a widely utilized flow diverter in the treatment of intracranial aneurysms.To assess incidence, clinical significance, predictors, and outcomes in-Pipeline stenosis (IPS).Angiographic studies 139 patients treated between 2011 2013 were independently reviewed by 2 authors for presence IPS. Multivariable logistic regression analysis was conducted to determine predictors IPS.A total 21 (15.8%) demonstrated some degree IPS during follow-up period at mean time...
BACKGROUND AND OBJECTIVES: First pass effect (FPE) is a metric increasingly used to determine the success of mechanical thrombectomy (MT) procedures. However, few studies have investigated whether duration procedure can modify clinical benefit FPE. We sought FPE after MT for anterior circulation large vessel occlusion acute ischemic stroke modified by procedural time (PT). METHODS: A multicenter, international data set was retrospectively analyzed treated who achieved excellent reperfusion...
OBJECTIVEInhibition of platelet aggregation is vital to preventing thromboembolic complications related stent placement in endovascular neurosurgery, but excessive inhibition potentiates hemorrhagic complications. Recent evidence suggests an ideal range 70-150 P2Y12 response units (PRU) as measured on the VerifyNow assay, which relies photometric measurements aggregation. Thromboelastography (TEG) with mapping (PM) alternative assay that directly measures clot formation and mechanical...
Background Although the liquid embolic agent, Onyx, is often preferred treatment for cerebral dural arteriovenous fistulas (DAVFs), there have only been a limited number of single-center studies to evaluate its performance. Objective To carry out multicenter study determine predictors complications, obliteration, and functional outcomes associated with primary Onyx embolization DAVFs. Methods From Consortium Dural Arteriovenous Fistula Outcomes Research (CONDOR) database, we identified...
Background The contact aspiration (CA) technique is often used to perform endovascular thrombectomy (EVT) for acute ischemic stroke (AIS); however, rescue strategies are necessary if CA fails achieve recanalization. This study investigates the outcomes of incorporating stent retriever (SR) in strategy following failed CA. Methods EVT patients with attempts were identified from a large multicenter registry and stratified by technique: alone or SR strategy. Outcomes included successful...
OBJECTIVE The definitive influence of prestroke disability on outcomes in patients with a low Alberta Stroke Program Early CT Score (ASPECTS) treated endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) due to large-vessel occlusion (LVO) remains unknown. This study aimed investigate the impact this specific population. METHODS Data from 32 international centers AIS-LVO ASPECTS who underwent EVT between January 2013 and December 2022 were analyzed retrospectively. Low defined as...
INTRODUCTION: Dural arteriovenous fistulae (dAVFs) are rare cerebrovascular anomalies. Tentorial dAVFs more likely to have aggressive features, making them prone symptomatic presentations and hemorrhage. METHODS: Patients from the Consortium for Arteriovenous Fistula Outcomes Research (CONDOR) database were queried age at treatment, sex, comorbidities, clinical presentation, arterial anatomy, venous Borden grade, surgical approach. The primary efficacy endpoint utilized was complete...
INTRODUCTION: Recanalization of occluded intracranial large vessels after endovascular thrombectomy (EVT) is often achieved following multiple attempts. Current literature does not offer any guidance regarding switching to alternative techniques (AT) a futile first attempt. METHODS: We included patients with stroke secondary vessel occlusion (LVO) who failed their attempt at recanalization either ICA or M1 segments utilizing an international multicenter cohort. Propensity score matching was...