A5101672406- Traumatic Brain Injury and Neurovascular Disturbances
- Shoulder and Clavicle Injuries
- Shoulder Injury and Treatment
- Spinal Fractures and Fixation Techniques
- Neurosurgical Procedures and Complications
- Spine and Intervertebral Disc Pathology
- Trauma and Emergency Care Studies
- Cerebrospinal fluid and hydrocephalus
- Cervical and Thoracic Myelopathy
- Neuroscience and Neuropharmacology Research
- Trauma Management and Diagnosis
- Orthopedic Surgery and Rehabilitation
- Heavy metals in environment
- Sarcoma Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Heavy Metals in Plants
- Intracerebral and Subarachnoid Hemorrhage Research
- Chromatin Remodeling and Cancer
- Algal biology and biofuel production
- Nuclear Physics and Applications
- Nerve Injury and Rehabilitation
- Radiology practices and education
- Spinal Hematomas and Complications
- Radioactivity and Radon Measurements
- Microbial Metabolic Engineering and Bioproduction
The University of Texas Health Science Center at Houston
2024
Harborview Medical Center
2021-2023
Neurological Surgery
2016-2023
University of Washington
2012-2023
Queens Hospital Center
2022
Icahn School of Medicine at Mount Sinai
2022
Mount Sinai Queens
2022
St. Barnabas Hospital
2022
New York City Health and Hospitals Corporation
2022
University of Ottawa
2008-2019
Surgical programs across the US continue to promote and invest in initiatives aimed at improving racial/ethnic diversity, but whether this translates changes percentage of applicants or matriculants from minority groups remains unclear.To examine trends surgical specialties who identified as part a group underrepresented medicine 2010-2011 2018-2019 academic years.This cross-sectional study examined self-reported identity among residency evaluate demographic 2010 2018. Data were obtained...
Here, the authors examined factors involved in volumetric progression of traumatic brain contusions. The variables significant this are identified, and expansion rate a bleed can now effectively be predicted given presenting characteristics patient.
Diffuse intrinsic pontine glioma (DIPG) is a universally fatal pediatric brainstem tumor affecting approximately 300 children in the US annually. Median survival less than 1 year, and radiation therapy has been mainstay of treatment for decades. Recent advances biological understanding disease have identified H3K27M mutation nearly 80% DIPGs, leading to 2016 WHO classification diffuse midline H3K27M-mutant, grade IV tumor. Developments epigenetic targeting transcriptional tendencies yielded...
Proximal humeral fractures, which occur mainly in older adults, account for approximately 4 to 5% of all fractures. Approximately 40% these fractures are displaced involving the surgical neck. Management this group is often challenging and outcome frequently unsatisfactory. In particular it not clear whether surgery gives better outcomes than non-surgical management. Currently there much variation use a lack good quality evidence inform decision. We aim undertake pragmatic UK-based...
Long-chain (35–40 carbons) alkenones are a unique class of lipids biosynthesized by certain species algae including the industrially grown marine microalgae Isochrysis. Their structures characterized very long linear carbon-chain with trans double bonds and methyl or ethyl ketone. A method is presented for isolation pure from Isochrysis biomass in parallel biodiesel production. Yields isolated relative to starting dry were routinely 3.5 12% (w/w), respectively. Alkenones then converted...
To determine if albuterol delivery by the combination of a metered-dose inhaler (MDI) with spacer is equal in effectiveness to nebulization pediatric emergency department setting.Prospective series.Urban children's hospital department.Patients > or = six years age diagnosis acute asthma exacerbation. Exclusion criteria consisted impending respiratory failure and corticosteroid administration within preceding seven days.Patients were randomized into either nebulizer treatment group one two...
In 1930 I<sup>1</sup>reported a case of allergy due to insulin affecting the gastro-intestinal tract and producing severe symptoms. Briefly, boy 12 years, having had diabetes since age 7, began have attacks abdominal pain, nausea vomiting. These were so in each instance as precipitate coma. After short stay hospital, with treatment consisting free intravenous infusions salt solution dextrose, child would return home, repeat experience when his usual diet therapy resumed. Several such...
BACKGROUND AND OBJECTIVES: Growing evidence supports prompt surgical decompression for patients with traumatic spinal cord injury (tSCI). Rates of concomitant tSCI and brain (TBI) range from 10% to 30%. Concomitant TBI may delay diagnosis intervention. Little is known about real-world management this common constellation that carries significant clinical consequences. This study aimed quantify the impact on timing in a national cohort tSCI. METHODS: Patient data were obtained National Trauma...
The two major Nicotiana tabacum tobacco cembranoids, (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol (1) and its C-4 epimer, exhibit a wide range of interesting biological activities. Although the tumorigenesis inhibition activity cembranoids have been known since mid 1980′s, only limited number investigations targeted their optimization structure-activity relationship. This study reports isolation new (1S,2E,4S,6E,8S,11E)-2,6,11-cembratriene-8-O-methyl-4,8-diol (3)...
Decompressive craniectomy (DC) is an effective, lifesaving option for reducing intracranial pressure (ICP) in traumatic brain injury (TBI), stroke, and other pathologies with elevated ICP. Most DCs are performed via a standard trauma flap shaped like reverse question mark (RQM), which requires sacrificing the occipital posterior auricular arteries can be complicated by wound dehiscence infections. The Ludwig Kempe hemispherectomy incision (Kempe) entails T-shaped incision, one limb from...
A simple method was developed for detection of Bacillus anthracis (BA) endospores and differentiation them from other species in the cereus group. Chemical profiles that include lipids (i.e., fatty acids), carbohydrates sugars), spore-specific biomarker, dipicolinic acid, were generated by one-step thermochemolysis (TCM) at 140 °C 5 min to provide specific biomarker signatures. Anthrose, which is a characteristic B. group bacteria, determined fragment produced TCM. Surprisingly, several...
Functional hemispherectomy/hemispherotomy is a disconnection procedure for severe medically refractory epilepsy where the seizure foci diffusely localize to one hemisphere. It an improvement on anatomical hemispherectomy and was first performed by Rasmussen in 1974. Less invasive surgical approaches refinements have been made improve freedom minimize morbidity complications. Key structures that are disconnected include 1) internal capsule corona radiata, 2) mesial temporal structures, 3)...
A case of leiomyosarcoma the nasal cavity and paranasal sinuses is presented along with a review medical literature. The clinicopathological aspects this tumor are discussed. mode treatment complete surgical excision close follow-up due to its high rate local recurrence. long-term survival recurrent disease in unusual.
Background Adhesive capsulitis is a common cause of stiff shoulder and may result in pain restriction movement. The study aimed to investigate the role hydrodilatation glenohumeral joint management adhesive capsulitis. Methods Patients referred from clinic underwent under ultrasound guidance. Of 209 for hydrodilatation, 163 procedure attended follow-up physiotherapy. Outcome measures were available 118 patients (58 men 60 women). Mean age group was 52.6 years. Results There statistically...
A convergent synthesis of a C<sub>1</sub>–C<sub>23</sub> fragment the archazolids has been completed based on high-yielding Stille coupling to construct substituted <i>Z</i>,<i>Z</i>,<i>E</i>-conjugated triene. After removal protecting groups, resulting tetrol exhibited evidence for inhibition vacuolar-type ATPase (V-ATPase) but not cyclooxygenase (COX) inhibitory activity.
We present a 71-year old woman treated with 14 days of 5 mg intraventricular caspofungin for Scedosporium apiospermum complex meningoencephalitis diagnosed after spinal fusion and instrumentation. Cerebrospinal fluid studies improved during therapy administration was well tolerated. Within weeks discontinuation, the patient experienced clinical deterioration disease progression. There are sparse data on efficacy safety administering caspofungin. While apparently safe, insufficient control in...