- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Hemoglobinopathies and Related Disorders
- Intracranial Aneurysms: Treatment and Complications
- Migraine and Headache Studies
- Iron Metabolism and Disorders
- Cerebral Venous Sinus Thrombosis
- Stroke Rehabilitation and Recovery
- Ophthalmology and Eye Disorders
- Pregnancy and preeclampsia studies
- Neurosurgical Procedures and Complications
- Neurological Disease Mechanisms and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Trigeminal Neuralgia and Treatments
- Sympathectomy and Hyperhidrosis Treatments
- CNS Lymphoma Diagnosis and Treatment
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Glycogen Storage Diseases and Myoclonus
- Blood Coagulation and Thrombosis Mechanisms
- Fetal and Pediatric Neurological Disorders
- Ocular Diseases and Behçet’s Syndrome
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
University of Padua
2012-2024
Ospedale Santa Corona
2022
Policlinico Universitario di Catania
2021
Azienda Ospedaliera di Padova
2018-2020
Institute of Neurological Sciences
2015-2017
Ca' Foncello Hospital
2012
Pain and Headache Center
2008-2012
Since the outbreak of COVID-19 epidemic which in our region, Veneto (Italy), dates back to February, we were confronted with several challenges, but a constant aim keeping Stroke Unit COVID-free. For this reason, addition creating dedicated hot-spot as pre-triage just outside Emergency Department, together Neuroradiology obtained mobile CT unit that could be used by COVID-positive or COVID-suspected patients. Furthermore, thanks collaboration colleagues from different specialties (Infectious...
<h3>BACKGROUND AND PURPOSE:</h3> Successful vessel recanalization in posterior circulation large-vessel occlusion is considered crucial, though the evidence of clinical usefulness, compared with anterior circulation, not still determined. The aim this study was to evaluate predictors favorable outcome and analyze effect first-pass thrombectomy. <h3>MATERIALS METHODS:</h3> A retrospective, multicenter, observational conducted 10 high-volume stroke centers Europe, including period from January...
Transient global amnesia (TGA) has been associated with an increased prevalence of internal jugular valve insufficiency and many patients report Valsalva-associated maneuvers before TGA onset. These findings have led to the assumption hemodynamic alterations in intracranial veins inducing focal hippocampal ischemia. We investigated this hypothesis control subjects.Seventy-five 75 age- sex-matched healthy subjects were enrolled into a cross-sectional study. Extracranial transcranial...
<h3>Objective</h3> To find early hemodynamic predictors of outcome and reperfusion injury in patients with acute ischemic stroke due to anterior circulation large artery occlusion (LAO) after endovascular treatment (EVT). <h3>Methods</h3> Serial transcranial color-coded sonography examinations assessed the vessel status cerebral hemodynamics 185 (109 [58.9%] men, mean age 69.5 ± 12.3 years) consecutive LAO soon after, at 48 hours 1 week EVT. <h3>Results</h3> Successful recanalization (odds...
Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a possible cause of multiple sclerosis (MS).The CoSMo study evaluated the association between CCSVI and MS.The primary end-point this multicentric, case-control was to compare prevalence patients with MS, other neurodegenerative diseases (ONDs) healthy controls (HCs). Color-coded duplex sonography performed by sonologist images were sent one three central sonologists for second reading. Agreement local or, in case...
Posterior scleritis is a rare cause of ocular pain, due to scleral inflammation, presenting with periocular pain on movement and decreased vision. Although anterior may be associated this condition, signs absent. We report case posterior scleritis, right-sided exacerbated by movements, irradiating the ipsilateral temple zygoma, not visual disturbances at onset. Diagnosis was made ultrasonography confirmed brain orbital MRI. Differential diagnosis facial in particular, affecting periorbital...
We describe the case of a 40-year-old woman, affected by episodic cluster headache, who presented with headache triggered exposure to high altitude. Her attacks were refractory sumatriptan, very effective at sea level, but responded oxygen. A pathophysiological mechanism is proposed.
Recanalization of chronic occlusion the common carotid artery (CCA) in patients with a history neck irradiation is challenging, both for vascular surgeons and interventional neuroradiologists. We describe case successful stenting radio induced right CCA 41-year-old patient neurological deterioration minor stroke due to cerebral hypoperfusion caused by concomitant bilateral arterial occlusions. Direct surgery surgical bypass were considered contraindicated. The endovascular approach was...
No current consensus exists on the best anesthetic management of ischemic stroke patients undergoing mechanical thrombectomy. Both conscious sedation (CS) and general anesthesia (GA) are currently considered valid strategies, yet managed under CS may require emergent conversion to GA, which has been associated with worse outcomes. The aim this study was analyze rate potential risk factors for GA during thrombectomy.Two-hundred twenty-seven consecutive acute anterior circulation treated...
Recanalization of chronic occlusion the common carotid artery (CCA) in patients with a history neck irradiation is challenging, both for vascular surgeons and interventional neuroradiologists. We describe case successful stenting radio induced right CCA 41-year-old patient neurological deterioration minor stroke due to cerebral hypoperfusion caused by concomitant bilateral arterial occlusions. Direct surgery surgical bypass were considered contraindicated. The endovascular approach was...
Introduction Current treatment guidelines for acute ischemic stroke do not recommend thrombolytic therapy in children and adolescents as data are still very scarce. Case Report: We report the case of a 15-year-old boy who suddenly developed severe left-sided weakness speech difficulty while stooling. Upon arrival at our Emergency Department, National Institute Health Stroke Scale (NIHSS) score was 18. Urgent neurovascular ultrasound showed distal occlusion right internal carotid artery...
ABSTRACT BACKGROUND AND PURPOSE Ultrasound contrast agents (UCAs) are routinely used to improve the visualization of intracranial arteries. Since a higher rate hemorrhage (ICH) has been observed in patients undergoing sonothrombolysis combination with UCAs, we conducted this study aim assessing safety and tolerability SonoVue® acute ischemic stroke due anterior circulation large artery occlusion (LAO) eligible intravenous thrombolysis and/or mechanical thrombectomy. METHODS Among 474...
Stroke and cerebral vasculopathy are leading causes of morbidity mortality in patients with sickle cell disease (SCD). Transcranial Doppler (TCD) is a reliable validated predictor stroke risk. Children conditional or abnormal TCD at an increased risk for stroke, which can be mitigated by red blood transfusion hydroxyurea. Elucidating the relationship between hemodynamics hemolytic anemia help identify novel therapeutic approaches to reduce dependence.This long-term, real-world study was...
Cervical arterial dissection (CAD) is a frequent and preventable cause of ischemic stroke in young patients. Several arguments suggest that genetic developmental disorders could play an important role as part multifactorial predisposition sporadic CAD.We present 2 cases patients with CAD association cutaneous lesions nonatherosclerotic multivessel arteriopathy.Our first patient was 17-year-old white girl sudden onset weakness her right upper limb. A magnetic resonance angiogram showed severe...