A5049145342- Multiple Sclerosis Research Studies
- Parkinson's Disease Mechanisms and Treatments
- Amyotrophic Lateral Sclerosis Research
- Peripheral Neuropathies and Disorders
- Polyomavirus and related diseases
- Reproductive System and Pregnancy
- Epilepsy research and treatment
- Prion Diseases and Protein Misfolding
- Neurological disorders and treatments
- Systemic Lupus Erythematosus Research
- Genetic Neurodegenerative Diseases
- Systemic Sclerosis and Related Diseases
- Botulinum Toxin and Related Neurological Disorders
- Hereditary Neurological Disorders
- Pharmacological Effects and Toxicity Studies
- Music Therapy and Health
- Reproductive tract infections research
- Cerebrovascular and Carotid Artery Diseases
- Glioma Diagnosis and Treatment
- Neurology and Historical Studies
- Myasthenia Gravis and Thymoma
- Neonatal and fetal brain pathology
- Alzheimer's disease research and treatments
- Acute Ischemic Stroke Management
- Viral Infections and Immunology Research
University of Ferrara
2016-2025
University of Parma
2018
Anna University, Chennai
2009-2015
University of Pavia
2015
Institute of Neurological Sciences
2014
Istituti di Ricovero e Cura a Carattere Scientifico
2014
Arcispedale Sant'Anna
2003-2013
University of Trento
2013
University of Verona
2010
IRCCS Ospedale San Raffaele
2010
Small fibre neuropathy (SFN), a condition dominated by neuropathic pain, is frequently encountered in clinical practise either as prevalent manifestation of more diffuse or distinct nosologic entity. Aetiology SFN includes pre-diabetes status and immune-mediated diseases, though it remains unknown. Due to their physiologic characteristics, small nerve fibres cannot be investigated routine electrophysiological tests, making the diagnosis particularly difficult. Quantitative sensory testing...
<b><i>Objective:</i></b> To perform a large and detailed epidemiologic study on restless legs syndrome (RLS) during pregnancy the puerperium. <b><i>Methods:</i></b> A structured clinical interview, assessing symptoms since beginning of pregnancy, was performed to population 642 pregnant women at time delivery follow-up evaluation (1, 3, 6 months after delivery). Main hematologic tests were also evaluated. woman considered affected if she met International RLS Study Group criteria for...
Broca's area has been considered, for over a century, as the brain centre responsible speech production. Modern neuroimaging and neuropsychological evidence have suggested wider functional role is played by this area. In addition to that it involved in syntactical analysis, mathematical calculation music processing, recently shown may play some language comprehension and, more generally, understanding actions of other individuals. As magnetic resonance imaging, one cortical areas activated...
Summary: Worldwide investigation of the epidemiology epilepsy has suggested wide variations in frequency convulsive disorders. However, descriptive studies general populations cannot be completely comparable because a remarkable methodological dishomogeneity definition epilepsy, classification seizures, and ascertainment, collection, selection cases. The position with regard to Mediterranean people was still little known, few presently available from Italy offer underestimates owing...
To verify the existence of a symptomatic form restless legs syndrome (RLS) secondary to multiple sclerosis (MS) and identify possible associated risk factors. Prospective, multicenter, case-control epidemiologic survey. Settings: Twenty sleep centers certified by Italian Association Sleep Medicine. Eight hundred sixty-one patients affected MS 649 control subjects. N/A. Data regarding demographic clinical factors, presence severity RLS, results hematologic tests, visual analysis cerebrospinal...
Although diffusion tensor imaging (DTI) and postmortem dissections improved the knowledge of white matter (WM) anatomy, functional information is lacking. Our aims are: to provide a subcortical atlas human brain functions; elucidate roles different bundles; probabilistic resection map WM.We studied 130 patients who underwent awake surgery for gliomas (82 left; 48 right) with electrostimulation mapping at cortical levels. Different aspects language, sensori-motor, spatial cognition, visual...
Objectives To assess the effects of active music therapy ( MT ) and individualized listening to (LtM) on behavioral psychological symptoms dementia BPSD s) in persons with PWD s). Design Randomized controlled trial. Setting Nine Italian institutions. Participants Persons moderate severe s (N = 120) were randomized one three treatments. Interventions All groups received standard care SC ), two attended 20 or LtM sessions, twice a week, addition . Measurements The Neuropsychiatric Inventory...
The temporo-parieto-occipital (TPO) junction is a complex brain territory heavily involved in several high-level neurological functions, such as language, visuo-spatial recognition, writing, reading, symbol processing, calculation, self-processing, working memory, musical and face object recognition. Recent studies indicate that this area covered by thick network of white matter (WM) connections, which provide efficient multimodal integration information between both local distant cortical...
Background: Obesity may be a risk factor for developing multiple sclerosis (MS). Objective: We examined if body size influences the of MS in population-based, case control study. Methods: A total 953 cases and 1717 controls from Norway 707 1333 Italy reported their by choosing silhouette 1 to 9 (largest) every fifth year age 5 30 at time The size-related was defined odds ratios (ORs) logistic regression analyses adjusting age, smoking outdoor activity. Results: In large (silhouettes 6–9)...
Objectives: The objective of this paper is to estimate the association between multiple sclerosis (MS) and measures sun exposure in specific age periods Norway Italy. Methods: A total 1660 MS patients 3050 controls from Italy who participated a multinational case-control study (EnvIMS) reported habits during childhood adolescence. Results: significant infrequent summer outdoor activity increased risk was found strongest ages 16 18 years (odds ratio (OR) 1.83, 95% confidence interval (CI)...
In this study, we employed a sensitive activity assay system to measure cerebrospinal fluid (CSF) and serum levels of active matrix metalloproteinase-9 (MMP-9) in 37 relapsing-remitting (RR), 15 secondary progressive (SP) nine primary (PP) multiple sclerosis (MS) patients, grouped according clinical magnetic resonance imaging (MRI) evidence disease activity. We also studied, as neurological controls, 48 patients with other inflammatory disorders (OIND) non-inflammatory (NIND). To assess...
<h3>Background</h3> Studies have reported circadian variation in the onset of ischemic stroke, which may carry important pathophysiological implications. However, there is no detailed information about variations among subtypes stroke. <h3>Objective</h3> To determine whether subgroups patients with stroke specific clinical characteristics would exhibit different patterns, to more systematically examine role possible triggering or precipitating factors. <h3>Design and Setting</h3> Analysis...
We carried out an intensive incidence, prevalence, and mortality survey of motor neuron disease (MND) in the province Ferrara, northern Italy. Based on 72 patients, mean incidence per year for period 1964 through 1982 was 0.98 cases 100,000. On December 31, 1981, prevalence rate 3.95 In 19-year average 0.83 100,000 year. The more common men, individuals aged 50 to 70 years, residents rural areas engaged agricultural work. A retrospective case-control study, confirming a significantly higher...
The antagonistic interaction between adenosine and dopamine receptors could have important pathophysiological therapeutic implications in Parkinson's disease (PD). primary aim of this study was to investigate the expression, affinity, density A1, A2A, A2B, A3 (ARs) D2 (D2Rs) PD. An increase A2AAR putamen found. presence functionality ARs human lymphocyte neutrophil membranes from patients with PD revealed a specific alteration compared healthy subjects. A statistically significant linear...
This investigation was conducted to clarify the epidemiology of ALS disease in Sardinia. During years 1965-1974, average annual incidence found be 0.64/100,000 inhabitants. On prevalence day, October 24th, 1974, rate 1.56/100,000 A significant male predominance found, rates for men and women being 0.88 0.40, respectively. The peak both sexes reached between 60 69 years. distribution study area uniform but its occurrence significantly higher among agricultural workers (5.28/100,000). started...
Pregnancy is a risk factor for transient restless legs syndrome, which usually recovers during the postdelivery period. The goal of present survey to investigate whether syndrome pregnancy represents later development syndrome.A long-term follow-up study, planned as an extension previous on pregnancy, was carried out. After mean interval 6.5 years, 207 parous women were contacted again compare incidence among subjects who never experienced symptoms with those reported previously investigated...