A5091817860- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Neurosurgical Procedures and Complications
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- Long-Term Effects of COVID-19
- Moyamoya disease diagnosis and treatment
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and healthcare impacts
- Peripheral Artery Disease Management
- Meningioma and schwannoma management
- Intracerebral and Subarachnoid Hemorrhage Research
- Sphingolipid Metabolism and Signaling
- Ocular Oncology and Treatments
- Abdominal vascular conditions and treatments
- Coronary Interventions and Diagnostics
- Ophthalmology and Eye Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Socioeconomic Development in MENA
- COVID-19 Clinical Research Studies
- Trigeminal Neuralgia and Treatments
- Vascular Malformations and Hemangiomas
Ain Shams University
2024
Health and Education Research Management and Epidemiologic Services (United States)
2023
Royal London Hospital
2021-2023
Centre Hospitalier Universitaire de Saint-Étienne
2014-2021
Inserm
2020
Université Claude Bernard Lyon 1
2020
Laboratoire CarMeN
2020
Institut National des Sciences Appliquées de Lyon
2020
Centre Hospitalier Universitaire de Lille
2012-2013
Hôpital Maison Blanche
2009-2011
Background and purpose Flow diversion is an innovative increasingly used endovascular treatment for intracranial aneurysms. Its initial evaluation with the first devices available showed good efficacy of this variable safety results. The Direction Endoluminal Device (FRED) has a specific design was evaluated in single-arm, multicenter, prospective, Good Clinical Practice study: SAFE (Safety Analysis FRED Embolic device aneurysm treatment). This analysis reports clinical results at 1 year...
Curative transvenous embolization is an emerging strategy for treatment of cerebral arteriovenous malformations (AVMs).To assess contemporary outcomes as a stand-alone therapy AVMs.We prospectively followed 40 patients with 41 AVMs who underwent endovascular between January 2008 and 2015. Patient demographics, AVM characteristics, techniques used, angiographic results, clinical outcomes, complications were assessed independently.Thirty-eight (92.6%) anatomically cured. The mean patient age...
Background Thromboembolic events and intraoperative rupture are the most frequent neurologic complications of intracranial aneurysm coiling. Their frequency has not been evaluated in recent series. Purpose To provide an analysis complications, clinical outcome, participant risk factors after coiling or balloon-assisted within Analysis Recanalization Endovascular Treatment Intracranial Aneurysm, ARETA, cohort. Materials Methods Sixteen neurointerventional departments prospectively enrolled...
Background and purpose To evaluate the safety effectiveness of low-profile braided intracranial stents called Low Profile Visualized Intraluminal Support (LVIS) devices for stent-assisted coil embolization wide-necked aneurysms. Materials methods This was a prospective, multicenter, observational study unruptured ruptured aneurysms treated with LVIS devices. Imaging clinical data were independently analyzed respectively by CoreLab Clinical Event Committee. Primary endpoints safety,...
Background and purpose Flow diverters are increasingly used for the treatment of intracranial aneurysms. Evaluation first devices available clinical use showed high efficacy this although safety results were worse compared with coiling or balloon-assisted coiling. The S afety Efficacy A nalysis F RED E mbolic Device in Aneurysm Treatment (SAFE) trial is a single-arm, multicenter, prospective study conducted to precisely analyze FRED Jr devices. Methods Unruptured recanalized aneurysms...
Vasospasm and delayed cerebral ischemia (DCI) are the leading causes of morbidity mortality after intracranial aneurysmal subarachnoid hemorrhage (aSAH). detection, prevention management, especially endovascular management varies from center to lacks standardization. We aimed evaluate this variability via an international survey how neurointerventionalists approach vasospasm diagnosis management.
Purpose To evaluate the feasibility, safety and efficacy of endovascular treatment with flow diverters in patients recanalized multitreated aneurysms a retrospective, multicenter, single-arm study. Methods The study included 29 who were treated by (Silk or Pipeline devices). Pre- post-procedural complications morbidity mortality rates evaluated functional outcomes (modified Rankin Score (mRS)) at 1 month (short-term) 3–4 months (mid-term) compared preoperative mRS (before procedure)....
Endovascular treatment is the first line therapy for management of ruptured and unruptured intracranial aneurysms, but delayed aneurysm rupture leading to bleeding/rebleeding can occur subsequently. ARETA (Analysis Recanalization after Treatment Aneurysm) a prospective, multicenter study conducted analyze recanalization. We analyzed bleeding rebleeding in this large cohort. 16 neurointerventional departments prospectively enrolled patients treated aneurysms between December 2013 May 2015...
Stroke is a devastating disease. Endovascular mechanical thrombectomy dramatically changing the management of acute ischemic stroke, raising new challenges regarding brain outcome and opening up avenues for protection. In this context, relevant experiment models are required testing therapies addressing important questions about infarct progression despite successful recanalization, reversibility lesions, blood-brain barrier disruption reperfusion damage. Here, we developed minimally...
BACKGROUND: Thromboembolic complications are the most common cause of periprocedural morbidity associated with endovascular treatment intracranial aneurysms detachable coils. OBJECTIVE: To estimate safety and efficacy using combined intra-arterial intravenous abciximab to treat thrombi complicating cerebral aneurysm coil embolization. METHODS: In a retrospective analysis 390 aneurysmal coiling procedures, we identified 39 patients (10.0%) thromboembolic events related procedure. As first...
Background The aim of this study was to assess the technical success and procedural safety new Silk Vista device (SV) by evaluating intraprocedural periprocedural complication rate after its use in several institutions worldwide. Methods involved a retrospective review multicenter data regarding consecutive series patients with intracranial aneurysms, treated SV between September 2020 January 2021. Clinical, intra/periprocedural angiographic data, including approach, materials used, aneurysm...
Background One limitation of the endovascular treatment intracranial aneurysms is aneurysm recanalization. The Analysis Recanalization after Endovascular Treatment Aneurysm (ARETA) study a prospective multicenter cohort evaluating factors associated with recanalization treatment. Methods current analysis focused on patients treated by coiling or balloon-assisted (BAC). Postoperative, mid-term vascular imaging, and evolution occlusion were independently evaluated two neuroradiologists. A...
Coiling, including balloon-assisted coiling (BAC), is the first-line therapy for ruptured and unruptured aneurysms. Its efficacy can be clinically evaluated by bleeding/rebleeding rate after coiling, anatomically aneurysm occlusion post-procedure during follow-up. We aimed to analyze immediate post-coiling associated factors within Analysis of Recanalization Endovascular Treatment intracranial Aneurysm (ARETA) population. Between December 2013 May 2015, 16 neurointerventional departments...
Background Coiling is the first-line treatment for management of unruptured intracranial aneurysms (UIAs), but delayed thromboembolic events (TEEs) can occur after such treatment. ARETA (Analysis Recanalization Endovascular Treatment Intracranial Aneurysm) a prospective multicenter study conducted to analyze aneurysm recanalization. We analyzed TEEs in UIA subgroup. Methods Sixteen neurointerventional departments prospectively enrolled patients treated ruptured and between December 2013 May...
The use of self-expanding stents to treat post-hemorrhagic cerebral vasospasm was recently described. We sought determine the clinical efficacy Cascade device delayed (DCV). performed benchside tests chronic outward force exerted by in comparison Solitaire.The (COF) M agile and L Agile tested with equivalent Solitaire 4x20mm. Further forces generated pre-formed tubes 1.5-6 mm were using both fully partially unsheathed Cascades. A retrospective review identify all patients aSAH DCV treated a...
Abstract Background Autotaxin (ATX) or ecto-nucleotide pyrophosphatase/ phosphodiesterase-2 is a secreted lysophospholipase D that hydrolyzes extracellular lysophospholipids into the lipid mediator lysophosphatidic acid, ligand for specific G protein-coupled receptors. Lysophosphatidic acid stimulates proliferation and contractility of hepatic stellate cells, key player in liver fibrogenesis, inhibits their apoptosis. Objective To determine serum ATX levels pediatric adolescent patients with...
The coronavirus disease 2019 (COVID-19) pandemic affected the healthcare system in a major way generally. Healthcare re-organization of resources and manpower, establishing management protocols specific patients' pathways are all evolving with continuously changing situation. Neuro-vascular its part these global measures to cope this establish less risky pathways, help triage, protecting staff by introducing training applying safety manage neuro-vascular emergencies elective activity. We...
Background and purpose To evaluate the feasibility, safety, efficacy of endovascular treatment with flow diverters (FD) in patients recanalised multitreated aneurysms, a retrospective, multicenter, single-arm study. Materials methods The study included 29 aneurysms who were treated by FDs (Silk or Pipeline device). Per post procedural complications morbidity mortality rates evaluated. Additionally, functional outcomes (mRS) at 1 month (short-term) 3–4 months (mid-term) compared pre-operative...