A5044391134- Cutaneous Melanoma Detection and Management
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Allergic Rhinitis and Sensitization
- Cardiac, Anesthesia and Surgical Outcomes
- Autoimmune Bullous Skin Diseases
- Aortic aneurysm repair treatments
- Cutaneous lymphoproliferative disorders research
- Traumatic Brain Injury and Neurovascular Disturbances
- Urticaria and Related Conditions
- Lymphoma Diagnosis and Treatment
- Nutrition and Health in Aging
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Respiratory Support and Mechanisms
- Childhood Cancer Survivors' Quality of Life
- Dementia and Cognitive Impairment Research
- Frailty in Older Adults
- Acute Ischemic Stroke Management
- Nonmelanoma Skin Cancer Studies
- Neurogenetic and Muscular Disorders Research
- Retinal Diseases and Treatments
- Dialysis and Renal Disease Management
- Neurosurgical Procedures and Complications
- Indoor Air Quality and Microbial Exposure
Université de Reims Champagne-Ardenne
2016-2025
Hospices Civils de Lyon
2025
Centre Hospitalier Universitaire de Reims
2015-2024
Cognition, Santé, Société
2024
Nantes Université
2024
Hôpital Robert-Debré
2013-2022
Hôpital Maison Blanche
2008-2021
Délégation Paris 5
2015
Sorbonne Paris Cité
2015
Université Paris Cité
2015
Therapeutic options for severe emphysema are limited. Lung volume reduction using nitinol coils is a bronchoscopic intervention inducing regional parenchymal and restoring lung recoil.To evaluate the efficacy, safety, cost, cost-effectiveness of in treatment emphysema.Multicenter 1:1 randomized superiority trial comparing with usual care at 10 university hospitals France. Enrollment patients occurred from March to October 2013, 12-month follow-up (last follow-up, December 2014).Patients (n =...
The activating mutation of MYD88 L265P is a frequent feature primary cutaneous diffuse large B-cell lymphoma, leg-type (PCLBCL-LT), reported in up to 69% the cases. Whether patients with display specific clinical and evolutive features has not been evaluated.To identify characteristics associated mutation, confirm its high prevalence, evaluate effect on prognosis PCLBCL-LT.A retrospective multicenter study was conducted using medical records from dermatology departments belonging French...
Dyspnea is very frequent in obese subjects. However, its assessment complex clinical practice. The modified Medical Research Council scale (mMRC scale) largely used the of dyspnea chronic respiratory diseases, but has not been validated obesity. objectives this study were to evaluate use mMRC subjects and analyze relationships with 6-minute walk test (6MWT), lung function biological parameters.Forty-five (17 M/28 F, BMI: 43 ± 9 kg/m2) included pilot study. daily living was evaluated by...
Objective: To investigate the diagnostic value of commercially available BP230 and BP180-NC16a enzyme-linked immunosorbent assays (ELISAs) in routine practice patients with bullous pemphigoid (BP).
<h3>Importance</h3> Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT), occurs in elderly patients and has been considered as a lymphoma with poor prognosis, estimated 5-year specific survival rates of approximately 50%. The hypothesis an improvement prognosis over time not studied. <h3>Objectives</h3> To evaluate this series investigate factors associated well the prognosis. <h3>Design, Setting, Participants</h3> A retrospective multicenter study was conducted including...
Although predisposing factors for bullous pemphigoid (BP) have been recently established, no clinical or immunologic yet identified to predict disease outcome.To identify risk BP relapse during the first year of treatment.Multicenter prospective study 120 consecutive patients with newly diagnosed in 8 French dermatology departments. Baseline and 6 follow-up visits were planned record activity collect blood samples measurement serum anti-BP180 anti-BP230 levels by means enzyme-linked...
Abstract Bullous pemphigoid (BP) is an inflammatory autoimmune bullous disease involving cytokines and proteases in the process of blister formation. Recently, IL-17 IL-23 were evidenced lesional skin serum BP patients at time diagnosis, but their involvement outcome has still not been investigated yet. We then analysed levels during first months follow-up upon treatment. Compared with age- sex- matched controls, high observed baseline ( P < 0.01), while was not. However, some expressed...
Evaluation of health-related quality life (HRQoL) in patients with Alzheimer's disease (AD) is necessary to ensure optimal management. Several scales for assessing HRQoL AD exist, particular the Quality Life Disease (QoL-AD), which includes an evaluation by caregiver patient's HRQoL. The aim this study was identify factors associated patient, and overall as assessed QoL-AD. Cross-sectional multicenter subjects aged 65 years older, mild moderate AD. scores from QoL-AD were recorded (3 scores,...
Background Thromboembolic events and intraoperative rupture are the most frequent neurologic complications of intracranial aneurysm coiling. Their frequency has not been evaluated in recent series. Purpose To provide an analysis complications, clinical outcome, participant risk factors after coiling or balloon-assisted within Analysis Recanalization Endovascular Treatment Intracranial Aneurysm, ARETA, cohort. Materials Methods Sixteen neurointerventional departments prospectively enrolled...
Life expectancy is increasing in most developed countries, and elderly people have the highest incidence of melanoma.To identify characteristics melanoma its management compared with younger patients.Retrospective population-based study incident cases primary 1621 patients stage I or II 2004 2008. Questionnaires administered to physicians a survey cancer registries pathology laboratories were used obtain data. The was conducted 5 regions northeastern France.Characteristics tumors,...
Abstract Background FIGHTDIGO study has shown the feasibility of handgrip strength (HGS) measurements in 201 consecutive digestive cancer patients undergoing chemotherapy. Objective This focuses on a secondary aim study: relationship between muscle mass and HGS. Design Two bilateral measures HGS were performed using Jamar dynamometer before start each The highest value was chosen for final evaluation. Dynapenia (loss strength) defined as < 30 kg (men) 20 (women). Muscle measured at lumbar...
Summary Introduction The diagnostic accuracy of gastric ultrasound in children has not been assessed thoroughly. We aimed to determine the sensitivity and specificity a qualitative examination antrum supine 45° semi‐recumbent position clinical algorithm for detecting fluid volume > 1.25 ml.kg ‐1 , reported represent an ‘at‐risk stomach’ pulmonary aspiration. Methods conducted prospective, observer‐blinded, randomised trial healthy fasted according current pre‐operative guidelines. An...
Objective Structured Clinical Examinations (OSCEs) are critical for assessing clinical competencies in medical education. While traditional teaching methods remain prevalent, this study introduces an innovative approach by evaluating the effectiveness of OSCE preparation podcast improving students' performance using nephrology as a proof concept. This novel method offers flexible and accessible format supplementary learning, potentially revolutionizing A mono-centric randomized controlled...
Abstract Background Acute kidney injury (AKI) requiring renal replacement therapy (RRT) is common in intensive care units (ICUs), yet optimal amikacin dosing this context remains poorly understood. Methods We conducted a prospective observational study across 18 French hospitals from April 2020 to January 2022. Adult ICU patients (aged > years) receiving their first dose while on RRT were included. Data demographics, modalities, dosing, and therapeutic drug monitoring collected. Using...
The strategy of treatment small unruptured intracranial aneurysms is complex because their presumably low risk rupture. A precise knowledge the perioperative complications in this specific subgroup mandatory. purpose study was to compare results endovascular ≤ 3 mm and > included Analysis Treatment by Endovascular Approach Nonruptured Aneurysms study.The 626 patients harboring 682 aneurysms. Perioperative adverse events clinical outcome were analyzed treated for (51 patients, 51 aneurysms)...