Christine Hoeffel

ORCID: 0000-0002-2551-3545
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About
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Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • Diverticular Disease and Complications
  • Colorectal Cancer Surgical Treatments
  • Gastrointestinal disorders and treatments
  • MRI in cancer diagnosis
  • Pancreatic and Hepatic Oncology Research
  • Adrenal and Paraganglionic Tumors
  • Gastrointestinal Tumor Research and Treatment
  • Anorectal Disease Treatments and Outcomes
  • Appendicitis Diagnosis and Management
  • Colorectal and Anal Carcinomas
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Gallbladder and Bile Duct Disorders
  • Gastric Cancer Management and Outcomes
  • Neuroendocrine Tumor Research Advances
  • Colorectal Cancer Screening and Detection
  • Advanced MRI Techniques and Applications
  • Intraperitoneal and Appendiceal Malignancies
  • Hormonal Regulation and Hypertension
  • Bone Tumor Diagnosis and Treatments
  • Inflammatory Bowel Disease
  • Medical Imaging and Pathology Studies
  • Soft tissue tumor case studies
  • Amoebic Infections and Treatments
  • Cholangiocarcinoma and Gallbladder Cancer Studies

Hôpital Robert-Debré
2015-2024

Centre Hospitalier Universitaire de Reims
2015-2024

Université de Reims Champagne-Ardenne
2015-2024

Centre de Recherche en Sciences et Technologies de l'Information et de la Communication
2018-2024

Centre de Recherche en Économie et Statistique
2018-2024

Hôpital Maison Blanche
2012-2023

Centre Hospitalier de Valenciennes
2023

Centre d'Excellence en Technologies de l'Information et de la Communication
2018-2021

Sorbonne Paris Cité
2019

Université Paris Cité
2002-2019

Liver biopsy is the gold standard for assessing fibrosis but has several limitations. We evaluated a noninvasive method, so-called diffusion-weighted magnetic resonance imaging (DWMRI), which measures apparent diffusion coefficient (ADC) of water, diagnosis liver in patients with chronic hepatitis C virus (HCV). analyzed 20 healthy volunteers and 54 HCV (METAVIR: F0, n = 1; F1, 30; F2, 8; F3, 5; F4, 10) prospectively included. Patients moderate-to-severe (F2-F3-F4) had hepatic ADC values...

10.1002/hep.21747 article EN Hepatology 2007-07-30

Do not tumble dry: Gadolinium-DOTA encapsulated into polysaccharide nanoparticles (GdDOTA⊂NPs) exhibited high relaxivity (r1=101.7 s−1 mM−1 per Gd3+ ion at 37 °C and 20 MHz). This relaxation rate is due to efficient Gd loading, reduced tumbling of the complex, hydrogel nature nanoparticles. The efficacy as a T1/T2 dual-mode contrast agent was studied in C6 cells (see picture). Detailed facts importance specialist readers are published "Supporting Information". Such documents peer-reviewed,...

10.1002/anie.201203190 article EN Angewandte Chemie International Edition 2012-08-02

To develop guidelines describing a standardised approach to patient preparation and acquisition protocols for magnetic resonance imaging (MRI), computed tomography (CT) ultrasound (US) of the small bowel colon, with an emphasis on inflammatory disease. An expert consensus committee 13 members from European Society Gastrointestinal Abdominal Radiology (ESGAR) Paediatric (ESPR) undertook six-stage modified Delphi process, including detailed literature review, create series statements...

10.1007/s00330-016-4615-9 article EN cc-by European Radiology 2016-10-18

The use of cross-sectional imaging techniques for the noninvasive evaluation small-bowel disorders is increasing. effectiveness magnetic resonance (MR) enterography Crohn disease, in particular, well described literature. In addition, MR has an evolving though less documented role to play other diseases, including various benign and malignant neoplasms arising isolation or polyposis syndromes such as Peutz-Jeghers, inflammatory conditions vasculitis treatment-induced enteritis, infectious...

10.1148/rg.325115088 article EN Radiographics 2012-09-01

Abstract Background The aim was to determine the incremental value of MRI compared with CT in preoperative estimation peritoneal carcinomatosis index (PCI). Methods and examinations patients were evaluated. images first analysed by two observers who determined a PCI (PCICT). Then, reviewed combination second (PCICT+MRI). sensitivity negative predictive imaging sets using surgery as reference standard (PCIRef). Results plus more accurate predicting surgical than alone. absolute difference...

10.1002/bjs.10527 article EN British journal of surgery 2017-04-04

The objective of this study was to build and validate a radiomic signature predict early poor outcome using baseline 2-month evaluation CT compare it the RECIST1·1 morphological criteria defined by changes in homogeneity borders.This is an ancillary from PRODIGE-9 multicentre prospective for which 491 patients with metastatic colorectal cancer (mCRC) treated 5-fluorouracil, leucovorin irinotecan (FOLFIRI) bevacizumab had been analysed. In 230 patients, computed texture analysis performed on...

10.1136/gutjnl-2018-316407 article EN Gut 2019-05-17

Purpose To determine whether texture features on pretreatment contrast material-enhanced computed tomographic (CT) images can help predict overall survival (OS) and time to progression (TTP) in patients with advanced hepatocellular carcinoma (HCC) treated sorafenib. Materials Methods This retrospective study included 92 HCC sorafenib between January 2009 April 2015 at two independent university hospitals. Sixty-four of the (70%) (six women, 58 men; median age, 66 years) were from institution...

10.1148/radiol.2018171320 article EN Radiology 2018-03-27

In patients with small intestinal neuroendocrine tumors (siNETs), surgical resection of the primary tumor and associated mesenteric lymph nodes (LNs) is recommended, but not well standardized can be risky in superior vessel involvement.We aimed to evaluate correlation between length resected bowel number removed LNs, propose a preoperative morphological classification siNET-associated LNs.The records operated on for siNETs at two expert centers August 2005 November 2013 were analyzed. Two...

10.1159/000441423 article EN Neuroendocrinology 2015-10-08
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