A5048248914- Inflammatory Bowel Disease
- Microscopic Colitis
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Diverticular Disease and Complications
- Diagnosis and treatment of tuberculosis
- Autoimmune and Inflammatory Disorders
- Appendicitis Diagnosis and Management
- Liver Disease and Transplantation
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Anorectal Disease Treatments and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Gastrointestinal Bleeding Diagnosis and Treatment
- MRI in cancer diagnosis
- Cancer, Lipids, and Metabolism
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Treatments and Studies
- Eosinophilic Esophagitis
- Renal cell carcinoma treatment
- Metabolism and Genetic Disorders
- Cancer, Hypoxia, and Metabolism
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2016-2025
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2015-2025
Hospital Clínic de Barcelona
2016-2025
Centro de Investigación Biomédica en Red
2009-2025
University College London
2024
Mayo Clinic in Arizona
2024
University of Calgary
2024
University of Ljubljana
2024
Ljubljana University Medical Centre
2024
Cleveland Clinic
2024
Assessment of disease extension and activity is crucial to guide treatment in Crohn's disease. The objective the current cross-sectional study was determine accuracy MR for this assessment.50 patients with clinically active (n = 35) or inactive 15) underwent ileocolonoscopy (reference standard) MR. T2-weighted precontrast postcontrast-enhanced T1-weighted sequences were acquired. Endoscopic evaluated by CDEIS (Crohn's Disease Index Severity); addition endoscopic lesions classified as absent,...
The management of patients with IBD requires evaluation objective tools, both at the time diagnosis and throughout course disease, to determine location, extension, activity severity inflammatory lesions, as well as, potential existence complications. Whereas endoscopy is a well-established uniformly performed diagnostic examination, implementation radiologic techniques for assessment still heterogeneous; variations in technical aspects degrees experience preferences exist across countries...
BackgroundThe use of magnetic resonance imaging (MRI) for assessment Crohn's disease (CD) is expanding. The aim this study to define and provide an external validation the MRI predictors active CD, severe a quantitative Magnetic Resonance Index Activity (MaRIA).
Evaluation of response to treatment is a key aspect in cancer therapy. Response Criteria Solid Tumors (RECIST) are used most oncology trials, but those criteria evaluate only unidimensional tumor measurements and disregard the extent necrosis, which target all effective locoregional therapies. Therefore, European Association for Study Liver (EASL) guidelines recommended that assessment should incorporate reduction viable burden. The current report provides an agreement/concordance between...
Chapter 4: Scores for Inflammatory Bowel Disease 4.1 Clinical and endoscopic scoring systems in IBD Statement 4.1.ECCO-ESGAR Diagnostics GL (2018) indices are useful standardizing disease activity.However, despite widespread use, no score has been validated clinical practice [EL5] ulcerative colitisThere several presently available to classify severity colitis (UC) within the multiple domains of activity, which aid objective assessment guide therapeutic monitoring strategies [1,2].Although...
The aim of this study was to describe the imaging features by contrast-enhanced ultrasound (CEUS) intrahepatic cholangiocarcinoma (ICC) in cirrhosis patients. We registered CEUS images patients with histologically confirmed ICC. In all cases magnetic resonance (MRI) done confirm diagnosis and/or staging purposes. A total 21 met criteria be included study. median nodule size 32 mm. All nodules showed contrast enhancement at arterial phase; 10 it homogeneous and 11 peripheral (rim-like)....
Abstract This study assesses the magnetic resonance (MR) features of intrahepatic cholangiocarcinoma (ICC) in patients with cirrhosis specific analysis contrast enhancement pattern. Cholangiocarcinoma may show increased uptake arterial phase, and, if washout delayed venous phase were to be detected, noninvasive diagnostic criteria proposed American Association for Study Liver Diseases guidelines would refuted. We reviewed MR findings 25 31 histologically confirmed ICC nodules. Signal...
Measurement of the component fibrosis in Crohn's disease (CD) may have important therapeutic implications. The aim this study was to characterize Magnetic Resonance Imaging (MRI) findings that are differentially associated with presence and those inflammatory activity, using pathological analysis surgically resected intestinal lesions as reference standard.MRI studies identical imaging protocol 41 CD patients who underwent elective bowel resection within 4 months before surgery were...
Sorafenib improves overall survival (OS) of patients with hepatocellular carcinoma (HCC) in the absence objective response. Thus, time to tumor progression (TTP) is used capture benefits novel molecular agents, but proof its surrogacy lacking. Furthermore, predictors upon are not established and there a need characterize postprogression (PPS) assess time-dependent covariates analysis if it influenced by pattern, solely simultaneous impairment liver function performance status. We...
This ECCO topical review of the European Crohn's and Colitis Organisation [ECCO] focused on prediction, diagnosis, management fibrostenosing disease [CD]. The objective was to achieve evidence-supported, expert consensus that provides guidance for clinical practice.
Background & AimsVedolizumab is a gut-selective monoclonal antibody for the treatment of moderately to severely active Crohn’s disease (CD). We performed prospective study endoscopic, radiologic, and histologic healing in patients with CD who received vedolizumab therapy.MethodsWe phase 3b, open-label, single-group 101 at least 3 months (a Activity Index [CDAI] score 220–450, simple endoscopic [SES-CD] 7 or more, 1 more mucosal ulcerations [identified by endoscopy], failure conventional...
Randomized controlled trials (RCTs) represent the gold standard for evidence generation across all areas of medicine and especially in oncology field, as they allow unbiased estimates treatment effect without confounders. Observational studies have many problems that could reduce their internal external validity. However, large prospective (well-conducted) observational real-world (RWS) can detect occurrence rare adverse events or monitoring long-term events. Impact Real Word Data (RWD),...