- Global Maternal and Child Health
- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- Vaccine Coverage and Hesitancy
- HIV Research and Treatment
- Pharmaceutical Economics and Policy
- Mobile Health and mHealth Applications
- HIV, Drug Use, Sexual Risk
- Health Systems, Economic Evaluations, Quality of Life
- Cervical Cancer and HPV Research
- Hepatitis B Virus Studies
- Healthcare Systems and Reforms
- Reproductive Health and Contraception
- Genital Health and Disease
- COVID-19 epidemiological studies
- HER2/EGFR in Cancer Research
- Acute Lymphoblastic Leukemia research
- Viral Infections and Outbreaks Research
- Healthcare Policy and Management
- Child Nutrition and Water Access
- Maternal and Perinatal Health Interventions
- Economic and Financial Impacts of Cancer
- Pneumonia and Respiratory Infections
- Medication Adherence and Compliance
- Chronic Myeloid Leukemia Treatments
National University of Singapore
2021-2024
National University Health System
2022-2024
Community Impact
2023
University of Washington
2013-2022
Seattle University
2011-2022
Center for Global Health
2022
Strategic Analysis (United States)
2019
Kenya Medical Research Institute
2018
Mercer Island School District
2013-2015
VillageReach
2014
BackgroundThe way in which a government chooses to finance health intervention can affect the uptake of interventions and consequently extent gains. In addition gains, some policies such as public insure against catastrophic expenditures. We aimed evaluate financial risk protection benefits selected that could be publicly financed by Ethiopia.MethodsWe used extended cost-effectiveness analysis assess gains (deaths averted) afforded (cases poverty bundle nine (among many other) Government...
Background. Measles remains an important cause of morbidity and mortality in children developing countries. Due to the success measles reduction elimination efforts thus far, WHO has raised question whether global eradication is economically feasible.
Introduction The availability of specialized HIV services is limited in rural areas sub‐Saharan Africa where the need greatest. Where are available, people living with (PLHIV) must overcome large geographic, economic and social barriers to access healthcare. objective this study was understand unique PLHIV face when accessing healthcare compared those not a area infrastructure. Methods We conducted population‐based cross‐sectional 447 heads household on Bugala Island, Uganda. Multiple linear...
A six-dose antimalarial regimen of artemether-lumefantrine (A/L) may soon become one the most widely used drug combination in Africa, despite possible constraints with adherence and poor absorption due to inadequate nutrition, a lack pharmacokinetic effectiveness data. Within trial supervised versus unsupervised A/L treatment stable Ugandan Plasmodium falciparum transmission setting, plasma lumefantrine concentrations were measured subset patients on day 3 (C [lum]day3) 7 [lum]day7)...
HIV/AIDS clinics in Uganda and other low-income countries face increasing numbers of patients workforce shortages. We performed a cost-effectiveness analysis comparing Pharmacy-only Refill Program (PRP), form task-shifting, to the Standard Care (SOC) at large clinic Uganda, Infectious Diseases Institute (IDI). The PRP was started reduce shortages optimize patient care by substituting pharmacy visits for SOC involving monthly physician accessing antiretroviral medicines.We used retrospective...
Abstract Objectives Health technology assessment (HTA) for a wide range of healthcare technologies is an essential component well-functioning health systems. Knowledge the use HTA in low- and middle-income countries (LMICs) limited. Methods We performed survey selected LMICs. interviewed key stakeholders on use, conduct challenges performing their countries. mixed-methods analyses to identify, characterize describe how it relates gross domestic product government effectiveness. Key findings...
The Fogg Behavior Model (FBM) is a new framework which posits that behavior happens when three factors - motivation, ability, and prompt occur in the same moment. FBM categorizes people into four groups based on motivation ability those with high will adopt prompted. Two rounds of panel survey data from 617 married men urban Pakistan were used to test this hypothesis. Multilevel mixed-effects logistic regression was for analysis. results show relationships between condom use be as...
Abstract Background An aim of this study is to introduce a practitioner-friendly behavior model. Few theories health explicitly take the effect social norms on into account. Generally, that do account assume operates through motivation. We use Fogg Behavior Model (FBM), model new public health, explore whether are associated with modern contraceptive among Nigerian women, and they affect motivation or ability. In other words, discourage contraception lower women’s ability contraception....
Mass drug administration of azithromycin to children in sub-Saharan Africa has been shown improve survival high-mortality settings. The period after hospital discharge is a time elevated risk unaddressed by current interventions and might provide an opportunity for targeting empirical administration. We aimed assess the efficacy administered at on death rehospitalisation Kenyan younger than 5 years.In this double-blind, placebo-controlled randomised trial, were randomly assigned (1:1)...
Lower-income countries face severe health worker shortages. Recent evidence suggests that this problem can be mitigated by task-shifting--delegation of aspects care to less specialized workers. We estimated the potential impact task-shifting on costs antiretroviral therapy (ART) and physician supply in Uganda. The study was performed at Infectious Diseases Institute (IDI) clinic, a large urban HIV clinic.We built an aggregate cost-minimization model from societal Ministry Health (MOH)...
In this study we use facility-level data from nationally representative surveys conducted in Ghana, Kenya, and Uganda to understand pharmaceutical availability within the three countries.In 2012, a survey capture information on pharmaceuticals other facility indicators over 200 facilities each country. We analyze of quantify its association with various indicators. both essential medicines, as defined by medicine lists (EMLs) respective country, all surveyed deemed important for treatment...
Objective Although adverse events (AEs) following voluntary medical male circumcision (VMMC) are rare, their prompt ascertainment and management is a marker of quality care. The use two-way text messaging (2wT) for client follow-up after VMMC reduces the need clinic visits (standard care (SoC)) without compromising safety. We compared cost-effectiveness 2wT to SoC post-VMMC in two, high-volume, public sites Zimbabwe. Materials methods developed decision-analytic (decision tree) model at two...
The demand for induced abortions in Uganda is high despite legal and moral proscriptions. Abortion seekers usually go to illegal, hidden clinics where procedures are performed unhygienic environments by under-trained practitioners. These abortions, which unsafe, lead a rate of severe complications use substantial, scarce healthcare resources. This study was estimate the costs associated with Uganda. A decision tree developed represent consequences abortion an average case. Data were obtained...
BACKGROUND Fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) tests are commonly used to assess human epidermal growth factor 2 (HER2) status of tumors patients with breast cancer. This analysis evaluates the likely cost‐effectiveness expanded retesting HER2 tumor women early stage METHODS We developed a decision‐analytic model estimate incremental ratio (ICER) reflex testing from US payer perspective. Expanded is defined as specimens whose IHC0, IHC1+, or FISH‐negative...
Over two thirds of women who need contraception in Uganda lack access to modern effective methods. This study was conducted estimate the potential cost-effectiveness achieving universal contraceptives by implementing a hypothetical new contraceptive program (NCP) from both societal and governmental (Ministry Health (MoH)) perspectives.A Markov model developed compare NCP status quo or current (CCP). The followed cohort 15-year old girls over lifetime horizon. Data were obtained National...
Background Rheumatic heart disease (RHD) prevalence and mortality rates remain especially high in many parts of Africa. While effective prevention treatment exist, coverage the various interventions are low. Little is known about comparative cost-effectiveness different RHD limited resource settings. We developed an economic evaluation tool to assist ministries health allocating resources planning control programs. Methodology/Principal Findings constructed a Markov model natural history...
Measles control has succeeded worldwide, and many countries have substantially reduced incidence mortality. This led to consideration of the feasibility measles elimination in Uganda within context global eradication. Before an program is initiated, it important consider its potential economic impact, including cost-effectiveness.Incremental cost-effectiveness ratios (ICERs) were estimated for mortality reduction Uganda. A dynamic age-structured compartmental model transmission was used...
To evaluate the acceptability and performance of cervical cancer (CC) screening using visual inspection with acetic acid (VIA) integrated into a rural immunization clinic in Uganda.We conducted cross-sectional pilot study Uganda. We explored associations between women's characteristics acceptance VIA testing. collected samples for Papanicolaou (Pap) smear testing random subset women used results from this test as comparator assessing performance.We enrolled 625 whom 571 (91.4%) accepted 54...