A5081076437- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Facial Trauma and Fracture Management
- Global Health and Surgery
- Reconstructive Surgery and Microvascular Techniques
- Global Health Care Issues
- Diversity and Career in Medicine
- Global Maternal and Child Health
- Climate Change and Health Impacts
- Breast Implant and Reconstruction
- Digital Imaging in Medicine
- Head and Neck Surgical Oncology
- Health disparities and outcomes
- dental development and anomalies
- Healthcare Systems and Reforms
- Trauma and Emergency Care Studies
- Global Health Workforce Issues
- Body Contouring and Surgery
- Tumors and Oncological Cases
- Traumatic Brain Injury and Neurovascular Disturbances
- Nasal Surgery and Airway Studies
- Reconstructive Facial Surgery Techniques
- Injury Epidemiology and Prevention
- Genetic Syndromes and Imprinting
- Nerve Injury and Rehabilitation
Children's Hospital of Philadelphia
2024-2025
Rady Children's Hospital-San Diego
2025
University of California, San Diego
2025
University of Washington
2017-2024
University of Pennsylvania
2024
Philadelphia University
2024
American Cleft Palate-Craniofacial Association
2024
Seattle Children's Hospital
2019-2023
Seattle University
2019-2023
Creative Commons
2016-2022
Government and nongovernmental organizations need national global estimates on the descriptive epidemiology of common oral conditions for policy planning evaluation. The aim this component Global Burden Disease study was to produce prevalence, incidence, years lived with disability from 1990 2017 by sex, age, countries. In addition, reports socioeconomic pattern in burden standard World Bank classification economies as well Socio-demographic Index. findings show that remain a substantial...
<h2>Summary</h2><h3>Background</h3> Accurate childhood cancer burden data are crucial for resource planning and health policy prioritisation. Model-based estimates necessary because surveillance scarce or non-existent in many countries. Although global incidence mortality available, there no previous analyses of the represented disability-adjusted life-years (DALYs). <h3>Methods</h3> Using Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2017 methodology, (ages 0–19 years) was...
Background Past research has shown how fires, heat and hot substances are important causes of health loss globally. Detailed estimates the morbidity mortality from these injuries could help drive preventative measures improved access to care. Methods We used Global Burden Disease 2017 framework produce three main results. First, we produced results on incidence, prevalence, years lived with disability, deaths, life lost disability-adjusted 1990 for 195 countries territories. Second, analysed...
Background The Global Burden of Disease Study (GBD) has historically produced estimates causes injury such as falls but not the resulting types injuries that occur. objective this study was to estimate global incidence, prevalence and years lived with disability (YLDs) due facial fractures leading injurious fracture. Methods We obtained results from GBD 2017. First, estimated incidence each cause (eg, falls), then proportion would result in fracture being most disabling injury. Incidence,...
Cleft lip and/or palate (CLP) is estimated to occur in 1 out of every 700 births, but for many people residing low- and middle-income countries this deformity may be repaired late life or not at all. This study aims analyze worldwide provider-perceived barriers the surgical repair CLP countries.From 2011 2014, Smile Train distributed a multiple-choice, voluntary survey healthcare providers identify areas need care worldwide. Data on provider-reported were aggregated by year, country, larger...
Background As global rates of mortality decrease, non-fatal injury have increased, particularly in low Socio-demographic Index (SDI) nations. We hypothesised this pattern would be demonstrated regard to bony hand and wrist trauma over the 27-year study period. Methods The Global Burden Diseases, Injuries, Risk Factors Study 2017 was used estimate prevalence, age-standardised incidence years lived with disability for 195 countries from 1990 2017. Individual injuries included fractures, thumb...
Background The WHO estimates a global shortage of 2.8 million physicians, with severe deficiencies especially in low and middle-income countries (LMIC). unequitable distribution physicians worldwide is further exacerbated by the migration from LMICs to high-income (HIC). This large-scale has numerous economic consequences which include increased mortality associated inadequate physician supply LMICs. Methods We estimate cost for due excess migration. To do so, we use concept value...
The objective of this study was to identify risk factors for free flap failure among various anatomically based subgroups.The 2005 2012 American College Surgeons National Surgical Quality Improvement Program database queried patients undergoing microvascular tissue transfer on current procedural terminology codes. Univariate analysis performed any association between and the following factors: age, gender, race, body mass index (BMI), diabetes, smoking, alcohol use, hypertension,...
Background Brazil boasts a health scheme that aspires to provide universal coverage, but its surgical system has rarely been analysed. In an effort strengthen systems worldwide, the Lancet Commission on Global Surgery proposed collection of 6 standardised indicators: 2-hour access surgery, workforce density, volume, perioperative mortality rate (POMR) and protection against impoverishing catastrophic expenditure. This study aims characterise Brazilian with these newly devised indicators...
Background: Orofacial clefts are one of the most common congenital anomalies, but this disease burden is unevenly distributed worldwide. The authors hypothesize that falls disproportionately on countries with smallest surgical workforce or lowest Socio-Demographic Index, rather than those highest prevalence disease. Methods: estimated and orofacial clefting from 1990 to 2017 in 195 using Global Burden Disease methodology. Prevalence disability-adjusted life-years were compared...
AMPA-type glutamate receptor (AMPAR) trafficking is essential for modulating synaptic transmission strength. Prior studies that have characterized signaling pathways underlying AMPAR identified the cAMP/PKA-mediated phosphorylation of GluA1, an subunit, as a key step in membrane insertion AMPAR. Inhibition ERK impairs insertion, but mechanism by which exerts its effect unknown. Dopamine, activator both PKA and ERK, induces relationship between two protein kinases process not understood. We...
The aim of this study is to report patterns burn injury within the United States from 1990 2016 with regard age, sex, geography, and year.Advances in management injuries as well successful public health efforts have contributed reductions annual incidence mortality burns. However, several studies suggest that these are not equally distributed throughout US population.The Global Burden Disease Study was utilized collect incidence, mortality, disability-adjusted life years (DALYs), lived...
Introduction: Little is known about rates of suicidal ideation and behavior among youth with cleft lip and/or palate (CLP) other craniofacial conditions. Methods: Records patients ages 6 older who were administered the Columbia-Suicide Severity Rating Scale (C-SSRS) Lifetime Version during routine multidisciplinary or team visits between 2019 2023 examined. Demographics information, C-SSRS data, diagnoses assessed statistics including t tests, Fisher exact test, odds ratios. Results: A total...
Gender dysphoria is estimated to occur in over 1 million people the United States. With decreasing stigma regarding transgender population, it likely more patients will seek medical and surgical gender transition as parts of their treatment. However, otolaryngologists may lack training gender-confirming surgery. This study aims determine current state transgender-related education States otolaryngology programs evaluate trainee perceptions importance such training.A cross-sectional survey...
In an era of outcomes-driven medicine, being able to benchmark complication rates various procedures is utmost importance. The readmission, reoperation, and adverse outcomes in abdominoplasty have been previously reported, although risk factors for these not thoroughly elucidated. This study aims identify specific independent readmission other abdominoplasty.This retrospectively reviewed the American College Surgeons National Surgical Quality Improvement Program identified all...
The decision to undertake rhinoplasty maneuvers during cleft lip repair remains controversial. Little data compare long-term outcomes with and without primary (PR). This study compared nasolabial in cohorts unilateral (UCL) treated PR at the Children's Hospital of Philadelphia using standardized aesthetic anthropometric assessments. Retrospective cohort study. Tertiary care pediatric hospital. Patients who underwent for UCL. Cleft PR. Anthropometric analyses crowdsourced assessments...
INTRODUCTION While severe macroglossia in Beckwith-Wiedemann syndrome (BWS) is often treated with tongue reduction surgery, most patients mild to moderate are nonsurgically managed. Given that outcomes for these conservatively managed not well characterized, this study aims describe the natural history of and BWS who did undergo early surgery. METHODS Records seen between 2004–2024 were reviewed. Conservative management was defined as having had surgery during first 3 years life....
Background: This study assesses long-term results of ear molding and factors associated with improved outcomes. Methods: Consecutive infants treated by a single surgeon from 2012 to 2023 were reviewed. Photographs before device application (time T0) within 6 months removal T1) collected. Satisfaction responses photographs T2) collected parents. Deformity severity at the 3 timepoints was determined participants recruited via crowdsourcing using 4-point scale. Results: Of 97 parent...