A5065130495- Contact Dermatitis and Allergies
- Occupational exposure and asthma
- Pesticide Exposure and Toxicity
- Allergic Rhinitis and Sensitization
- Dermatology and Skin Diseases
- Immunotoxicology and immune responses
- Drug-Induced Adverse Reactions
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Historical and Scientific Studies
- Psoriasis: Treatment and Pathogenesis
- Autoimmune Bullous Skin Diseases
- Pharmaceutical studies and practices
- Autoimmune and Inflammatory Disorders
- Food Allergy and Anaphylaxis Research
- Surgical Sutures and Adhesives
- Traumatic Ocular and Foreign Body Injuries
- Nail Diseases and Treatments
- Sympathectomy and Hyperhidrosis Treatments
- Antimicrobial agents and applications
- Oral Health Pathology and Treatment
- Infection Control and Ventilation
- Biosimilars and Bioanalytical Methods
- Rabies epidemiology and control
- Animal testing and alternatives
- Chemistry and Chemical Engineering
Gentofte Hospital
2015-2025
University of Copenhagen
2016-2025
Copenhagen University Hospital
2022-2025
Bispebjerg Hospital
2014-2022
ABSTRACT Background Despite legislation aimed to protect the population against skin sensitization in European Union (EU), over one quarter of general is sensitised at least chemical. Objectives To provide an overview and comparison concerning sensitization. In addition, we gathered opinions experts stakeholders regarding improvements risk assessment process EU, suggestions for improvement. Methods Legislation was identified compared. Four questionnaires were created towards industry,...
Occupational contact dermatitis is frequent, and further understanding of the epidemiology will improve basis its prevention. Objectives. To identify occupations at risk for severe occupational dermatitis.The last 1000 cases seen our department were identified.The study population comprised 618 females 382 males. The mean age onset irritant was significantly lower than allergic both sexes, irrespective presence atopic dermatitis. Females high cooks, butchers, beauticians, bakers,...
The use of methylisothiazolinone (MI) in cosmetic products has caused an unprecedented epidemic MI contact allergy. Current data concerning exposures at a European level are required.To describe demographics and for patients with allergy.Eleven dermatology departments from eight countries prospectively collected between 1 May 31 October 2015 among consecutive who had positive patch test reactions to (2000 ppm aq.).A total 6.0% (205/3434; range 2.6-13.0%) MI. Dermatitis most frequently...
Summary Background Occupational contact dermatitis among hairdressers is frequent, owing to daily exposure irritants and allergens. Objectives To identify sensitization the most common allergens associated with occupation of hairdressing. Methods Patch test results 399 1995 matched controls dermatitis, registered by Danish Contact Dermatitis Group between January 2002 December 2011, were analysed. All patients patch tested European baseline series, additionally hairdressing series. Results (...
In view of the current and unprecedented increase in contact allergy to methylisothiazolinone (MI), we characterized evaluated two recent epidemics preservatives used cosmetic products address failures risk assessment management.To evaluate temporal trends preservative allergy.The study population included consecutive patch tested eczema patients seen at a university hospital between 1985 2013. A total 23 138 were investigated for overall prevalence least one increased significantly over...
Summary Background In recent years, the prevalence of contact allergy to isothiazolinones has reached epidemic levels. Few studies have presented data on occupations at risk developing isothiazolinones. Objectives To present demographics and examine factors for sensitization methylisothiazolinone ( MI ), methylchloroisothiazolinone MCI ) in combination with benzisothiazolinone BIT D anish dermatitis patients. Materials methods A retrospective epidemiological analysis from three hospitals...
Summary Background Irritant contact dermatitis ( ICD ) is a common diagnosis in patients with occupational OCD ). Studies are lacking on the usefulness of material safety data sheets MSDS s) making . Objective To characterize irritant exposures leading to OICD ), and evaluate occurrence concomitant allergens. Methods We included 316 suspected hand dermatitis, referred D epartment ermato‐ A llergology, C openhagen U niversity H ospital G entofte, enmark during J anuary 2010– ugust 2011,...
Summary Background An increasing incidence of contact allergy to methylisothiazolinone (MI) has been seen, caused, in particular, by cosmetic products and paints. A study from 2015 showed that 93.0% paints bought five European countries contained MI. New regulations have discussed for the EU, which may influenced this market. Objectives To re‐evaluate use concentrations MI four other isothiazolinones water‐based wall Methods Water‐based white (n = 60) were purchased retail stores countries:...
Summary Background Blue‐collar workers have a high risk of occupational contact dermatitis, but epidemiological studies are scarce. Objectives To investigate allergic dermatitis in blue‐collar with registered by the D anish C ontact ermatitis G roup. Methods A retrospective analysis patch test data from 1471 and matched controls tested between 2003 2012 was performed. logistic regression used to for associations. Results The often had hand ( p < 0.001). Atopic less commonly observed among...
BackgroundIn the light of exceptionally high rates contact allergy to preservative methylisothiazolinone (MI), information about cross‐reactivity between MI, octylisothiazolinone (OIT) and benzisothiazolinone (BIT) is needed.
Abstract Background Rubber accelerators are used in the production of rubber gloves and may cause contact allergy. Objectives To estimate long‐term trend prevalence allergy to for a 30‐year period Denmark, high‐risk occupations, exposures. Methods Data from all patients with dermatitis consecutively patch tested at department Skin Allergy Gentofte hospital European baseline series (EBS) 1990 2019, were analysed. Further, under suspicion accelerator additionally patch‐tested specialised 2005...
Secukinumab (anti-IL17A) is effective as treatment for moderate to severe plaque psoriasis, but real-life data on effectiveness and safety lack. We aimed present of all Danish patients treated with secukinumab (n = 69). At baseline, before initiation 300 mg (47.8%) or off-label 150 (52.2%), the median PASI score was 7.1. A total 66.7% (34/51) 52.9% (27/51) still at week 12 achieved a (Psoriasis Area Severity Index)-50 PASI-75 52.9%, respectively. 83.0% (44/53) 60.4% (32/53) had PASI-score <...
Contact dermatitis in healthcare workers is a world wide problem. We conducted retrospective observational study of the patch-test results 1402 and matched controls with contact who were treated at 3 hospitals departments Denmark between 2007 2014. The primary objective was to determine whether work associated allergy thiuram mix. Unadjusted univariate analyses revealed that significantly occupational hand dermatitis. mix more common having dermatitis, older age. In conclusion, we report...
Chemicals used for the manufacturing of rubber are known causes allergic contact dermatitis on hands. Recent European studies have suggested a decrease in thiuram allergy. Moreover, while an association with hand is well established, we recently observed several clinical cases facial to rubber.To evaluate temporal trends allergy accelerators from baseline series tertiary patch test clinic Denmark, and examine associations anatomical locations dermatitis.Patch data collected Danish...
Abstract Background Formaldehyde is a common cause of contact allergy. Hidden formaldehyde, that is, formaldehyde in products without releasers, has previously been detected cosmetic products. Objectives The objective this study was to investigate the content and causes hidden leave‐on Methods release from 142 products, primarily creams, analysed using chromotropic acid (CA) method. included 130 with no releasers on ingredient list 12 releasers. Products positive CA, ≥2.5 ppm, were...
The diagnosis of combined allergic and irritant contact dermatitis is an accepted subdiagnosis for hand dermatitis, it often considered in a patient with positive relevant patch test result, wet work exposure. We therefore hypothesize that arbitrary exposure to be taken into consideration newly diagnosed allergy. Furthermore, overestimation the will probably occur if criteria are applied correctly, as many occupations have element work.To find statistically expected number cases 1000...