A5037317867- Dermatology and Skin Diseases
- Contact Dermatitis and Allergies
- Acne and Rosacea Treatments and Effects
- Allergic Rhinitis and Sensitization
- Nail Diseases and Treatments
- Dermatological diseases and infestations
- Autoimmune Bullous Skin Diseases
- Asthma and respiratory diseases
- Urticaria and Related Conditions
- Skin Diseases and Diabetes
- Dermatological and Skeletal Disorders
- Nonmelanoma Skin Cancer Studies
- Systemic Sclerosis and Related Diseases
- Vascular Tumors and Angiosarcomas
- Dermatological and COVID-19 studies
- Dermatologic Treatments and Research
- Sarcoma Diagnosis and Treatment
- Leprosy Research and Treatment
- Cutaneous lymphoproliferative disorders research
- Drug-Induced Adverse Reactions
- Chemotherapy-related skin toxicity
- Histiocytic Disorders and Treatments
- Genetic and rare skin diseases.
- Oral Health Pathology and Treatment
- Psoriasis: Treatment and Pathogenesis
Ospedale Policlinico San Martino
2018-2025
University of Genoa
2018-2025
ORCID
2021
There is limited epidemiological evidence on outcomes associated with dupilumab exposure during pregnancy; monitoring pregnancy in large populations required.
Abstract Background Tralokinumab has demonstrated efficacy in the treatment atopic dermatitis (AD) both clinical trials and real-world settings. However, limited data exists on long-term use of tralokinumab Objective A multicentric Italian study, evaluating tralokinumab's drug survival (DS) up to 18 months among 471 patients with severe AD was conducted. Methods EASI (Eczema Area Severity Index), P-NRS (Pruritus Numerical Rating Scale), SD-NRS (Sleep Disturbance NRS), DLQI (Dermatology Life...
ABSTRACT Introduction Propolis is a sticky substance produced by honeybees from plant resins collected locally growing vegetation. Its chemical composition varies depending on the species visited bees. Contact dermatitis commonly reported following exposure to cosmetics containing propolis or intake of food supplements. Objectives To investigate prevalence contact allergy in two dermatology clinics Europe. Methods From February July 2023, consecutive adult patients were patch tested...
Background/Objectives: Tralokinumab, a fully human monoclonal antibody targeting IL-13, has shown efficacy and safety in clinical trials real-life studies for atopic dermatitis (AD). However, data on its effectiveness across AD phenotypes are limited. Methods: A multicentric study evaluated tralokinumab’s over 52 weeks 416 severe patients. EASI (Eczema Area Severity Index), P-NRS (Pruritus Numerical Rating Scale), DLQI (Dermatology Life Quality ADCT (Atopic Dermatitis Control Tool) were...
Ivermectin is a drug approved for the treatment of papulopustular rosacea (PPR). Although clinical guidelines recommend use ivermectin as first-line in patients with almost clear and mild rosacea, studies concerning its on them are lacking. This study investigated effectiveness tolerability to severe assessed antiparasitic effect Demodex mites. retrospective based 50 affected by PPR treated topical 1% once daily over 16 weeks. The disease severity, patient-examined improvement, safety...
We present the case of a 24-year-old Caucasian man, who developed scaly erythematous skin rash after second dose coronavirus disease 2019 (COVID-19) vaccination with Comirnaty (BNT162b2, BioNTech/Pfizer; Pfizer, New York, NY, USA) and proved positive for Epstein-Barr virus (EBV) reactivation. The severe acute respiratory syndrome 2 (SARS-CoV-2) mRNA vaccines have been associated an up-regulated T helper type 1-cell response, possibly favoring immune system imbalance. Also, EBV reactivation...
Topical ivermectin is an anti-inflammatory and anti-Demodex drug for papulopustular rosacea. Rosacea a relapsing disease the time between recurrences should be considered alongside efficacy.The aims of this study were to assess first relapse rates Demodex mite infestation rosacea.We conducted prospective subjects affected by different degrees Patients that achieved complete response after treatment monitored every 4 weeks up 32 additional weeks. For each patient, we evaluated recording rate...
Allergic contact dermatitis (ACD) is a common inflammatory skin disease caused by delayed hypersensitivity to chemical and biotic allergens. ACD significantly affects the patients' quality of life negatively impacting both occupational non-occupational settings. Patch testing gold standard diagnostic in vivo test precise etiology correctly perform prevention. According Italian Medicines Agency (AIFA) legislative decree no. 178 29
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The dermoscopic findings of papulopustular rosacea include tiny papules and pustules, follicular plugs dilatation. Demodex tails openings are indicators that mainly found in primary demodicosis and, less frequently, rosacea.To describe the features to investigate differential between patients with without concomitant infestation.We conducted a prospective study almost-clear, mild or moderate rosacea. For each patient, images were taken standardized skin surface biopsy was performed.In this...
Traditionally, KOH microscopy and fungal culture are the two preferred tests as gold standard for diagnosis of onychomycosis. Recently, other diagnostic methods have been developed to improve microbiological diagnosis. The EUROArray dermatomycosis kit is a PCR-based microarray test system detection direct identification species that most frequently involved in skin nail infections.Our primary aim was evaluate real-life applicability onychomycoses. In addition, we compared aetiology...
Conventional photodynamic therapy (c-PDT) is an effective treatment for actinic keratoses (AKs) and nonmelanoma skin cancer which exploits the photosensitizing properties of methyl aminolaevulinate (MAL). Daylight (DL-PDT) alternative to c-PDT does not require application MAL in occlusion that better tolerated by patients. The impact on efficacy DL-PD has been investigated previous studies.
Imiquimod 5% cream is an approved treatment for actinic keratoses, superficial basal cell carcinomas, and anogenital warts. Severe systemic side effects associated with imiquimod are rare, although a few cases of erythema multiforme Stevens-Johnson syndrome have been described. We present case topical two carcinomas.
Abstract Demodex mite proliferation is frequently involved in the pathogenesis of rosacea. The gold standard for identification microscopic examination on a standardized skin surface biopsy. However, this method sampling can be distressing and painful, especially when performed hairy sites. In case-control study, we compared sensitivity PCR diagnosing infestation. Moreover, investigated possible correlations between presence mites clinical characteristics. total, 20 patients affected by...
The increased proliferation of Demodex mites in the pilosebaceous unit can be cause rosacea flare-ups on face. Signs and symptoms scalp (e.g., itching, dandruff) have sometimes been reported patients with papulopustular face; they may due to a scalp.