A5061275208- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Gynecological conditions and treatments
- Uterine Myomas and Treatments
- Endometrial and Cervical Cancer Treatments
- Cutaneous Melanoma Detection and Management
- Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Pregnancy and preeclampsia studies
- Sarcoma Diagnosis and Treatment
- Ectopic Pregnancy Diagnosis and Management
- Melanoma and MAPK Pathways
- Salivary Gland Tumors Diagnosis and Treatment
- Prenatal Screening and Diagnostics
- Maternal and fetal healthcare
- Cancer and Skin Lesions
- Cervical Cancer and HPV Research
- COVID-19 Impact on Reproduction
- Dermatological and COVID-19 studies
- Tumors and Oncological Cases
- Assisted Reproductive Technology and Twin Pregnancy
- Parvovirus B19 Infection Studies
- Neuroendocrine Tumor Research Advances
- Soft tissue tumor case studies
University of Bari Aldo Moro
2016-2025
Second Affiliated Hospital of Luohe Medical College
2024
Candiolo Cancer Institute
2023
University of Turin
2023
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
2013-2022
Azienda Ospedaliera Santa Maria Degli Angeli
2021
Saudi Center for Organ Transplantation
2002
University of Foggia
2002
Institute of Normal and Pathological Physiology of the Slovak Academy of Sciences
2000
European Institute of Oncology
1999
study question: What is the prevalence of chronic endometritis (CE) in women with repeated unexplained implantation failure (RIF) at IVF, and how does antibiotic treatment affect reproductive outcome?summary answer: Chronic endometritis, associated infection common bacteria or mycoplasma, complaining RIF significantly improves outcome a subsequent IVF cycle.what known already: We have reported that CE frequent finding pregnancy loss higher rate successful pregnancies was achieved after...
The correlations between chronic endometritis and unexplained infertility are unexplored.We performed a retrospective study on consecutive patients referred to our hysteroscopy service due infertility. All women underwent endometrial sampling with histological cultural examinations. If was diagnosed, received antibiotic therapy, resolution subsequently ascertained by examination. We aimed estimate prevalence the effects of therapy spontaneous conception during year following hysteroscopy.A...
Distant metastases are unusual at presentation and during the course of ovarian carcinoma. The aim present study was to determine incidence prognostic factors distant consistent with stage IV disease in cancer patients. A retrospective chart review conducted on 162 patients epithelial carcinoma treated our Unit between 1991 2000. Pertinent clinical information, pathologic data, treatment, for survival following documentation metastatic were collected. significance association status various...
At fluid hysteroscopy the presence of endometrial micropolyps (less than 1 mm size) is a frequent finding. Although their origin still unknown, in our experience they are associated with stromal edema, thickening and periglandular hyperhaemia that suggest existence chronic endometritis. This study will aim to describe these lesions evaluate inflammatory significance by comparing hysteroscopic histological findings.820 women underwent biopsy. Sensitivity, specificity, positive negative...
Female-to-male transition remains a specific clinical indication for long-term testosterone administration. There is limited number of studies dealing with the effect androgen treatment on their female receptive targets (mainly breast and uterus) knowledge in this field scarce and, sometimes, contradictory. We performed prospective study including 12 patients aged between 20 years 32 years, diagnosis gender dysphoria, treated parenteral administration before sexual reassignment surgery....
The effects of coronavirus disease 2019 caused by severe acute respiratory syndrome 2 on pregnant women and neonates are mainly unknown, since limited data available in the literature. We conducted a monocentric cross-sectional study enrolling 122 un-vaccinated with COVID-19 infection tested RT-PCR nasopharyngeal swab. Only 4.1% patients had symptoms together major intensive care unit admission, whereas 35.25% comorbidities two-thirds them were overweight or obese. was detected third...
Chronic endometritis (CE) is a subtle pathology causing infertility and abnormal uterine bleeding. We evaluated the reliability of vaginal cervical cultures for detecting infectious agents at endometrial level.In prospective diagnostic study, 181 women diagnosed with CE 100 controls underwent vaginal, endocervical sampling. Cultures common bacteria, Neisseria gonorrhoeae, yeast Ureaplasma urealyticum PCR Chlamydia trachomatis were performed.The prevalent level bacteria(59.7% cases); U. was...
Cancerogenesis is characterized by increase of differentiated myofibroblasts. Mast cells (MCs) exert powerful effects on fibroblasts through a variety mediators. We investigated α-smooth-muscle actin (α-SMA(+) ) and CD34(+) fibroblasts, density toluidine blue-stained (MCs-TB) tryptase-immunolabelled MCs (MCs-Try) in 30 primary breast tumours.Tumour (T), peri-tumoral (PT) non-tumoral (NT) tissue was studied immunohistochemistry electron microscopy. MCs-TB MCs-Try increased gradually from NT...
The study of SARS-CoV-2 positive pregnant women is some importance for gynecologists, obstetricians, neonatologists and themselves. In recent months, new works have tried to clarify what happens at the fetal–placental level in virus, different pathogenesis mechanisms been proposed. Here, we present results a large series placentas Coronavirus disease (COVID) women, reference center COVID-positive pregnancies, on which conducted histological, immunohistochemical electron microscopy...
In recent years, the preferentially expressed antigen in melanoma (PRAME) has also been used histopathological diagnosis of melanocytic lesions, order to understand if it could constitute a valid, inexpensive, and useful resource dermatopathological fields. We performed double-center study evaluate whether data on usefulness possible limitations PRAME be confirmed by our group. From 1 December 2021 29 March 2022, we collected 275 cases lesions that were immunostained with (Ab219650) rabbit...
Ovarian cancer (OC) is the most lethal gynecologic characterized by an elevated apoptosis resistance that, potentially, leads to chemo-resistance in recurrent disease. Mitochondrial oxidative phosphorylation was found altered OC, and mitochondria were proposed as a target for therapy. Molecular evidence suggests that deregulation of mitochondrial biogenesis, morphology, dynamics, involved carcinogenesis. However, these processes remain be investigated OC. Eighteen controls 16 OC tissues...
The application of artificial intelligence (AI) algorithms in medicine could support diagnostic and prognostic analyses decision making. In the field dermatopathology, there have been various papers that trained for recognition different types skin lesions, such as basal cell carcinoma (BCC), seborrheic keratosis (SK) dermal nevus. Furthermore, difficulty diagnosing particular melanocytic Spitz nevi melanoma, considering grade interobserver variability among dermatopathologists, has led to...
The most common effects reported by the Italian Medicine Agency following administration of SARS-CoV-2 vaccine are myalgia, soreness to arm inoculation, fever, and asthenia. To date, there no specific official reports registered on possible alterations menstrual cycle, or female reproductive system, vaccine. Actually, clinical experience showed a spread transient adverse drug reactions all COVID-19 types, both mRNA Adenovirus vectored ones. In this work, we conducted first retrospective...