A5090345459- Reproductive System and Pregnancy
- Reproductive Biology and Fertility
- Endometriosis Research and Treatment
- Prenatal Screening and Diagnostics
- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Gynecological conditions and treatments
- Pluripotent Stem Cells Research
- Reproductive Health and Technologies
- Uterine Myomas and Treatments
- Pregnancy and preeclampsia studies
- Sperm and Testicular Function
- Reproductive Physiology in Livestock
- Renal and related cancers
- Estrogen and related hormone effects
- CRISPR and Genetic Engineering
- Reproductive Health and Contraception
- Endometrial and Cervical Cancer Treatments
- Genetic Syndromes and Imprinting
- Ectopic Pregnancy Diagnosis and Management
- Reproductive tract infections research
- Tissue Engineering and Regenerative Medicine
- MicroRNA in disease regulation
- Genomic variations and chromosomal abnormalities
- Ovarian cancer diagnosis and treatment
Universitat de València
2016-2025
INCLIVA Health Research Institute
2016-2025
Beth Israel Deaconess Medical Center
2019-2025
Harvard University
2019-2025
Beth Israel Deaconess Hospital
2019-2024
Baylor College of Medicine
2017-2024
Ghent University Hospital
2024
Vrije Universiteit Brussel
2023-2024
Institut de Recherche en Santé, Environnement et Travail
2024
École des Hautes Études en Santé Publique
2024
This retrospective longitudinal study was undertaken in order to determine the incidence and reproductive impact of uterine malformations on women desiring conceive during their years. A total 3181 patients whom morphology uterus ascertained by hysterosalpingography (HSG) laparoscopy/laparotomy years 1980-1995 included study. The population analysed fertile, infertile sterile patients. overall frequency 4.0%. Infertile (6.3%) had a significantly (P < 0.05) higher Müllerian anomalies,...
The influence of elevated serum progesterone levels during in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles on pregnancy rates is a matter continued debate among fertility clinicians. Efforts to resolve this question have been impeded by the various assays used measure and different, arbitrary threshold values for defining 'high' levels. A non-interventional, retrospective, observational, single-centre cohort study evaluated relationship between day human chorionic...
Journal Article Outcome of patients with endometriosis in assisted reproduction: results from in-vitro fertilization and oocyte donation Get access C. Simón, Simón Instituto Valenciano de Infertilidad (IVI), Department Paediatrics, Obstetrics Gynaecology, Valencia University School MedicineValencia, Spain Search for other works by this author on: Oxford Academic PubMed Google Scholar A. Gutiérrez, Gutiérrez Vidal, Vidal M.J. los Santos, Santos J.J. Tarín, Tarín J. Remohí, Remohí Pellicer 1...
BACKGROUNDThe Fifth Evian Annual Reproduction (EVAR) Workshop Meeting discussed knowledge regarding contemporary genetics in female reproduction.
Differential methylation between the two alleles of a gene has been observed in imprinted regions, where one allele occurs on parent-of-origin basis, inactive X-chromosome females, and at those loci whose is driven by genetic variants. We have extensively characterized substantial range normal human tissues, reciprocal genome-wide uniparental disomies, hydatidiform moles, using combination whole-genome bisulfite sequencing high-density microarrays. This approach allowed us to define profiles...
Elevated serum progesterone levels at the end of follicular phase in controlled ovarian stimulation (COS) leads to a poorer ongoing pregnancy rate IVF cycles due reduced endometrial receptivity. The objective this study was use microarray technology compare gene expression profiles window implantation according circulating progesterone. For prospective cohort study, data were obtained from biopsies 12 young healthy oocyte donors undergoing COS with pituitary suppression by either...
Significance We provide evidence of a decidualization defect in the endometrium women with severe preeclampsia (PE) that was detected at time delivery and persisted years after affected pregnancy. went on to link this impaired cytotrophoblast invasion. The transcriptional signature could enable its detection before (or after) conception, which would aid development therapies focused improving perhaps preventing PE.
Could cell therapy using autologous peripheral blood CD133+ bone marrow-derived stem cells (BMDSCs) offer a safe and efficient therapeutic approach for patients with refractory Asherman's syndrome (AS) and/or endometrial atrophy (EA) wish to conceive? In the first 3 months, therapy, BMDSCs in conjunction hormonal replacement increased volume duration of menses as well thickness angiogenesis processes endometrium while decreasing intrauterine adhesion scores. AS is characterized by presence...
During embryo implantation, the blastocyst interacts with and regulates endometrium, endometrial fluid secreted by epithelium nurtures embryo. Here, we propose that maternal microRNAs (miRNAs) might act as transcriptomic modifier of pre-implantation Microarray profiling revealed six 27 specific, miRNAs were differentially expressed in human during window implantation – a brief phase receptivity to released into fluid. Further investigation hsa-miR-30d, expression levels which most...
Abstract Background Previous evidence indicates associations between the female reproductive tract microbiome composition and outcome in infertile patients undergoing assisted reproduction. We aimed to determine whether endometrial microbiota is associated with outcomes of live birth, biochemical pregnancy, clinical miscarriage or no pregnancy. Methods Here, we present a multicentre prospective observational study using 16S rRNA gene sequencing analyse fluid biopsy samples before embryo...